Han Xu

ORCID: 0000-0002-4147-9965
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About
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Research Areas
  • Additive Manufacturing and 3D Printing Technologies
  • 3D Printing in Biomedical Research
  • Injection Molding Process and Properties
  • biodegradable polymer synthesis and properties
  • Manufacturing Process and Optimization
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Silicone and Siloxane Chemistry
  • Electrospun Nanofibers in Biomedical Applications
  • Epoxy Resin Curing Processes
  • Synthesis and properties of polymers

Athlone Institute of Technology
2022-2023

Shannon Applied Biotechnology Centre
2023

The use of biodegradable polymers in tissue engineering has been widely researched due to their ability degrade and release components a controlled manner, allowing for the potential regeneration tissues. Melt blending is common method controlling degradation rate these polymers, which involves combining materials molten state create homogenous mixture with tailored properties. In this study, polycaprolactone (PCL) was melt blended hydrophilic poly (ethylene oxide) (PEO) different molecular...

10.3390/macromol3030026 article EN cc-by Macromol—A Journal of Macromolecular Research 2023-07-03

This study explores the innovative production of personalized bilayer tablets, integrating two advanced manufacturing techniques: Droplet Deposition Modeling (DDM) and Injection Molding (IM). Unlike traditional methods limited to customizing dense medicines, our approach uses Additive Manufacturing (AM) effectively adjust drug release profiles. Focusing on Caffeine Paracetamol, we found successful processing for both DDM IM using formulation. The high viscosity Paracetamol formulation posed...

10.1016/j.ijpharm.2024.123859 article EN cc-by International Journal of Pharmaceutics 2024-02-02

Since 3D printing allows for patient-specific dosage forms, it has become a major focus in pharmaceutical research. However, is difficult to scale up drug product manufacturing. Injection molding been used conjunction with hot-melt extrusion mass produce products, but making tailored solid forms this technology neither cost-effective nor simple. This study explored the use of combination fused filament fabrication and injection create forms. A tablet fixation location template was overprint...

10.3390/pharmaceutics15020507 article EN cc-by Pharmaceutics 2023-02-03

Abstract In this paper, a hybrid manufacturing method combining the advantages of injection molding (IM) in terms efficiency and high precision with those three‐dimensional printing (3DP) minimum waste degree freedom is described to produce mixed‐material bilayer tensile specimens. 3DP was first utilized fabricate polylactic acid substrates four varied geometries two infill densities an overmolding technique employed finish manufacture using acrylonitrile butadiene styrene under IM pressure....

10.1002/app.53972 article EN Journal of Applied Polymer Science 2023-04-19

Mass customization is the development of items tailored to specific customers, but produced at low unit cost in high-volume. In this context, hybrid manufacturing (HM) combines fused deposition modeling (FDM) and injection molding (IM) fabricate a single personalized part with minimum cost. technique, inserts different physical features are first FDM-fabricated then IM-overmolded. This study investigated effect FDM-IM production technology, FDM insert geometry on mechanical properties,...

10.3390/polym14245413 article EN Polymers 2022-12-10

Additive manufacturing (AM) possesses a transformative potential to revolutionize personalized medicine fabrication. Fused filament fabrication (FFF), an advanced AM technique, enables the development of tailored medicines with customizable dosages and controlled release properties. Nevertheless, prerequisites impose material limitations present considerable challenges, necessitating comprehensive evaluation mechanical, rheological, thermal characteristics circumvent complications during FFF...

10.1016/j.ijpharm.2023.123400 article EN cc-by International Journal of Pharmaceutics 2023-09-09
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