- Digital Radiography and Breast Imaging
- Medical Imaging Techniques and Applications
- AI in cancer detection
- Breast Lesions and Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Effects of Radiation Exposure
- Breast Cancer Treatment Studies
- MRI in cancer diagnosis
- Radiation Dose and Imaging
- Cancer and Skin Lesions
- Abdominal Surgery and Complications
- Ovarian cancer diagnosis and treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Genomics, phytochemicals, and oxidative stress
- Endometriosis Research and Treatment
- Glutathione Transferases and Polymorphisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Venous Thromboembolism Diagnosis and Management
- Meningioma and schwannoma management
- Thyroid Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Brain Metastases and Treatment
- Radiopharmaceutical Chemistry and Applications
- Global Cancer Incidence and Screening
- Esophageal and GI Pathology
Radiology Associates
2022-2023
Weatherford College
2022
University of Pennsylvania
2016-2022
Abramson Cancer Center
2022
Hospital of the University of Pennsylvania
2019-2021
Philadelphia University
2018
Children's Hospital of Philadelphia
2018
University of Tennessee at Knoxville
2015
Thomas Jefferson University Hospital
2015
Vanderbilt University
2011-2015
Background Limited data exist beyond prevalence rounds of digital breast tomosynthesis (DBT) screening. Purpose To compare DBT outcomes over multiple years and to mammography (DM) Materials Methods Retrospective analysis included 1 year DM 5 screening (September 2011 September 2016); 67 350 examinations were performed in 29 310 women. Recall rate (RR) percentage, cancer detection (CDR) per 1000 women screened, false-negative positive predictive value recall (PPV1) biopsies sensitivity,...
PURPOSE Although mammography is the standard of care for breast cancer screening, dense tissue decreases mammographic sensitivity. We report prevalent detection rate (CDR) from first clinical implementation abbreviated magnetic resonance imaging (AB-MR) as a supplemental screening test in women with breasts. METHODS The study was approved by institutional review board and Health Insurance Portability Accountability Act complaint. This retrospective includes who were imaged between January 1,...
Background Digital breast tomosynthesis (DBT) has been shown to improve screening outcomes compared with digital mammography (DM) alone. However, little is known about differences in cancer conspicuity between DM and DBT or by mammographic view. Purpose To compare of cancers at versus view, craniocaudal (CC) mediolateral oblique (MLO). Materials Methods Lesion was graded three readers using a 0-5 numerical scale on both images from combined studies for 197 consecutive screening-detected...
Fluorine 18 (18F) fluorodeoxyglucose (FDG) PET/CT has shown promise for use in assessing treatment response patients with bone-only or bone-dominant (BD) metastatic breast cancer (mBC). In this single-institution, prospective single-arm study of 23 women (median age, 59 years [range, 38–81 years]) biopsy-proven estrogen receptor–positive BD mBC about to begin new endocrine therapy between October 3, 2013, and August 2018, the value early 4-week 18F-FDG predicting progression-free survival...
Breast MRI is the most sensitive modality for detection of breast cancer. However, false-negative cases may occur, in which cancer not visualized at and instead diagnosed with another imaging modality. The authors describe causes results, can be categorized broadly as secondary to perceptual errors or cognitive errors, nonvisualization nonenhancement tumor. Tips strategies avoid these are discussed. Perceptual occur when an abnormality prospectively identified, yet examination technically...
Abstract Background Pneumatosis Intestinalis (PI) is a rare complication following hematopoietic stem cell transplant (HSCT). We sought to assess the incidence, risk factors, and outcome associated with PI. Procedure retrospectively reviewed incidence of PI among 178 patients who underwent allogeneic HSCT between September 1999 February 2010. Results Eighteen children (10.1%) received developed at median 94 days (range, 11–1169) after transplant. All presented either abdominal pain or...
Microglandular adenosis (MGA) of the breast is exceedingly rare, with only a few case reports and series published to date. Previous studies have elegantly demonstrated progression benign MGA atypical MGA-in situ carcinoma invasive therefore suggest as possible non-obligate precursor lesion subset carcinomas. Immunohistochemically, negative for estrogen receptor (ER), progesterone (PR), HER2-neu oncoprotein expression, carcinomas arising in setting are often reported be triple negative. In...
Abstract Brain metastasis from papillary thyroid carcinoma is uncommon. Concurrent cerebral and pulmonary metastases rare, especially in pediatric patients. We report a case of brain revealed on post-therapy 131 I scan 12 year old girl with cancer who also had diffuse which were partially responsive to sequential therapy.
The purpose of this study was to assess the accuracy parametric analysis transvaginal contrast-enhanced ultrasound (TV-CEUS) for distinguishing benign versus malignant ovarian masses. A total 48 masses (37 and 11 borderline/malignant) were examined with TV-CEUS (Definity; Lantheus, North Billerica, MA; Philips iU22; Medical Systems, Bothell, WA). Parametric images created offline a quantification software (Bracco Suisse SA, Geneva, Switzerland) map color scales adjusted such that abnormal...
Abstract The development of late normal tissue damage secondary to radiation therapy can be a significant problem for cancer survivors. Pulmonary toxicity resulting from radiation-induced fibrosis represents an insidious injury that manifest itself 6 24 months after irradiation and continue progress over period years. While dosimetric parameters affect risk pulmonary are well described, less is known about genetic susceptibility. transcription factor Nrf2 (Nuclear (erythroid-derived 2)-like...
This study seeks to understand the value of ventilation imaging in pregnant patients imaged for suspected pulmonary embolism (PE). Ventilation-perfusion (VQ) scans this high-risk population were compared ventilation-only scans. We hypothesize that relatively healthy population, exclusion will not impact rate interpreted as positive. retrospective blinded comparative reader on collated VQ performed course routine clinical care a > 5 year period (03/2012 07/2017). Each set and perfusion only...