B M Thomas

ORCID: 0000-0002-0399-5512
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About
Contact & Profiles
Research Areas
  • Diverticular Disease and Complications
  • Dementia and Cognitive Impairment Research
  • Acute Lymphoblastic Leukemia research
  • Colorectal Cancer Screening and Detection
  • Urological Disorders and Treatments
  • Colorectal Cancer Surgical Treatments
  • Cardiac Arrest and Resuscitation
  • Airway Management and Intubation Techniques
  • Pediatric Urology and Nephrology Studies
  • Mechanical Circulatory Support Devices
  • Tracheal and airway disorders
  • Gastrointestinal disorders and treatments
  • Urinary Tract Infections Management
  • Colorectal and Anal Carcinomas
  • Ureteral procedures and complications
  • Drug-Induced Adverse Reactions
  • Acute Myeloid Leukemia Research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Inflammatory Bowel Disease
  • Palliative Care and End-of-Life Issues
  • Pelvic floor disorders treatments
  • DNA Repair Mechanisms
  • Anorectal Disease Treatments and Outcomes
  • Respiratory Support and Mechanisms
  • Anesthesia and Sedative Agents

Bryn Mawr Hospital
2024

Main Line Health
2024

Einstein Healthcare Network
2024

Rowan University
2022-2023

New Jersey Urology
2022

Stratford University
2022

Johns Hopkins Hospital
2011-2012

Womack Army Medical Center
2012

Sidney Kimmel Comprehensive Cancer Center
2012

Mayo Clinic in Florida
2012

Incorporation of cytarabine into DNA activates checkpoint kinase 1 (Chk1), which stabilizes stalled replication forks, induces S-phase slowing, and diminishes cytotoxicity. The selective Chk1 inhibitor SCH 900776 abrogates cytarabine-induced arrest enhances cytotoxicity in acute leukemia cell lines leukemic blasts vitro. To extend these findings to the clinical setting, we have conducted a phase I study 900776.Twenty-four adults with relapsed refractory leukemias received timed sequential,...

10.1158/1078-0432.ccr-12-2442 article EN Clinical Cancer Research 2012-10-24

Abstract A balloon filled with barium has been used to simulate a soft stool for the radiological study of disorders defaecation. Lateral radiographs demonstrate level pelvic floor in relation pubococcygeal line, change anorectal angle and behaviour anal sphincters. In 12 patients faecal incontinence, successfully treated surgically by postanal sphincter repair, was reduced from 135°±4·4° (s.e.m.) 103°±4·1° junction rose 1·5±0·4 cm. 10 slow-transit constipation there no descent on straining....

10.1002/bjs.1800710109 article EN British journal of surgery 1984-01-01

Two hundred and thirty-nine patients underwent colonoscopy for unexplained rectal bleeding. Local anorectal conditions were excluded by digital proctosigmoidoscopic examinations results of barium studies negative all patients. A cause bleeding was found in 95 Thirty-nine had adenomatous polyps, 24 unrecognised inflammatory bowel disease, most importantly 23 (10% series) carcinomas. Forty diverticular but nine them to have an polyp four a carcinoma. Colonoscopy can contribute positively the...

10.1136/bmj.2.6153.1685 article EN BMJ 1978-12-16

Submandibular gland excision is an operation frequently performed by many different surgical specialists. It often associated with a variety of postoperative complications, the commonest being neurological deficits related to damage marginal mandibular, lingual or hypoglossal nerves. Other patients develop further problems at later date due development calculi from gravel retained in duct remnant. This study aims discuss how these complications can be avoided.

10.1097/00006534-198705000-00049 article EN Plastic & Reconstructive Surgery 1987-05-01

tions are radiographs, and there also quite a few drawings ultrasonograms.

10.1136/pgmj.58.679.322 article EN Postgraduate Medical Journal 1982-05-01

10.1016/s0009-9260(83)80228-1 article EN Clinical Radiology 1983-01-01

10.1016/s0009-9260(79)80142-7 article EN Clinical Radiology 1979-01-01

10.1016/s0009-9260(05)80518-5 article EN Clinical Radiology 1991-08-01

10.1016/j.cacc.2009.11.004 article EN Current Anaesthesia and Critical Care 2009-12-18

Clusters of high incidence areas presenile Alzheimer's disease were found in Scotland between 1974 and 1988. We present a novel index case kinship based on the number observed common ancestors cases compared with expected order to evaluate whether these cluster are attributable familial cases. One county was Lanarkshire, 69 451 national 185 1794 any-cause dementia None shared great-grandmother there no instance where an individual case's another grandmother. Five pairs great-grandmother; for...

10.1097/00041444-199724000-00002 article EN Psychiatric Genetics 1997-01-01

Bladder stones represent approximately 5% of all cases urolithiasis and are typically identified managed long before causing irreversible renal injury. We present a case man in his 40s with prior history gunshot wound to the abdomen who presented leakage from previously healed suprapubic tube tract was found have giant bladder stone resulting He subsequently underwent combined open cystolithotomy vesicocutaneous fistulotomy during hospitalisation, which helped improve function. In addition...

10.1136/bcr-2023-256204 article EN BMJ Case Reports 2024-04-01

Between 1974 and 1988, discrete areas within Scotland had unexpectedly high incidences of presenile Alzheimer's disease. To examine whether these clusters might be attributable to ‘familial’ cases occurring in the same locality, we performed a case-control study parental cause death entered on certificates. Cases comprised (1) 145 disease patients (2) 73 vascular dementia presenting Lothian between 1988. Two control individuals per case, sex, born registration district, whose fathers...

10.1097/00041444-199724000-00001 article EN Psychiatric Genetics 1997-01-01

In this case report, we present a patient with low velocity fall resulting in thoracoabdominal blunt trauma made occult by the absence of reported history or external physical signs and symptoms. Delayed grade 3 renal laceration concomitant 2 hepatic was result that being treated for septicemia setting urinary tract infection, aspiration pneumonia, anticoagulation new-onset atrial fibrillation. This mismatch initial presentation severity delayed hemorrhagic process multiple visceral organs...

10.52768/2766-7820/1824 article EN Journal of Clinical Images and Medical Case Reports 2022-05-09
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