- Obstructive Sleep Apnea Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiovascular and Diving-Related Complications
- Neuroscience of respiration and sleep
- Lung Cancer Treatments and Mutations
- Mollusks and Parasites Studies
- Nutrition and Health in Aging
- Palliative Care and End-of-Life Issues
- Gallbladder and Bile Duct Disorders
- Frailty in Older Adults
- Pancreatic and Hepatic Oncology Research
- Genital Health and Disease
- Renal cell carcinoma treatment
- Global Cancer Incidence and Screening
- Prostate Cancer Diagnosis and Treatment
- Parasite Biology and Host Interactions
- Cervical Cancer and HPV Research
- Peptidase Inhibition and Analysis
- Helminth infection and control
- Grief, Bereavement, and Mental Health
- Cancer Diagnosis and Treatment
- Patient Dignity and Privacy
- Colorectal Cancer Screening and Detection
- Hip and Femur Fractures
- Multiple and Secondary Primary Cancers
Khon Kaen University
2015-2024
Songklanagarind Hospital
2018
Chulalongkorn University
2015
Frailty is a state of increased risk unfavorable outcomes when exposed to stressors, and COPD one the several chronic illnesses associated with condition. However, few studies have been conducted regarding prevalence its related factors in Southeast Asia. The objectives this study were determine frailty patients identify these populations. A cross-sectional who attended clinic was from May 2015 December 2016. Baseline characteristics collected, diagnosis based on FRAIL (fatigue, resistance,...
Abstract Background Hypertensive crisis is an urgent/emergency condition. Although obstructive sleep apnea (OSA) in resistant hypertension has been thoroughly examined, information regarding the risk factors and prevalence of hypertensive co-existing OSA limited. This study thus aimed to determine for patients with caused by OSA. Methods The inclusion criteria were age 18 years or over diagnosis hypertension. Those other causes secondary excluded. Patients categorized occurrence crisis....
In 2003, the JNC 7 reported obstructive sleep apnea (OSA) as a cause of secondary hypertension. The prevalence OSA in hypertension ranges from 30-80%. There are limited data on and risk factors hypertensive patients. This study thus aimed to evaluate clinical predictors these patients.This was cross-sectional conducted at clinic Khon Kaen University's Srinagarind Hospital, Thailand. We enrolled patients with treated clinic. defined apnea-hypopnea index 5 events/hour or over according...
This study aimed to assess the diagnostic accuracy and sensitivity of a YOLOv4-tiny AI model for detecting classifying hip fractures types.In this retrospective study, dataset 1000 pelvic radiographs was divided into training set consisting 450 fracture normal images (900 total) testing 50 (100 total). The were each manually augmented with bounding box drawn around hip, labeled either (1) normal, (2) femoral neck fracture, (3) intertrochanteric or (4) subtrochanteric fracture. Next, deep...
Cholangiocarcinoma patients usually have poor treatment outcome and a high mortality rate. The role of adjuvant chemotherapy (AC) is controversial. Our study aimed to evaluate benefits AC in resectable cholangiocarcinoma patients.A retrospective included 263 who underwent curative resection Srinakarind University Hospital. These had pathological reports showing clear margin (R0) or microscopic (R1) lesion-free tissue.There were 138 received AC. This group significantly lower mean age than...
Eosinophilic meningitis, caused by the nematode Angiostrongylus cantonensis, is prevalent in northeastern Thailand, most commonly adults. Data regarding clinical manifestations of this condition children limited and may be different those A chart review was done on 19 eosinophilic meningitis patients aged less than 15 years Srinagarind Hospital, Faculty Medicine, Khon Kaen University, Thailand. Clinical outcomes were reported using descriptive statistics. All had presented with severe...
Background: Effective treatments for cholangiocarcinoma (CCA) are still lacking. There promising results of checkpoint inhibitor programmed cell death ligand-1 (PD-L1) activities in early phase trials. This study aimed to investigate the expression PD-L1 and its relation possible CCA. Methods: Formalin-fixed paraffin-embedded tumor samples from 46 patients with were retrieved. was evaluated by immunohistochemistry using anti-PD-L1 antibody, clone 5H1. A positive response on cells defined as...
Febrile neutropenia (FN) is a serious complication following chemotherapy and associated with significant mortality financial expenditure. The aim of this study was to evaluate risk factors for longer length stay (LOS) cost treatment among hospitalized adults cancer who developed febrile in Thailand.Information on illness inpatients casualties came from hospitals nationwide hospital withdrawals the 3 health insurance schemes fiscal 2010. data covered 96% population were analyzed by age...
Family caregivers of older cancer patients face many challenges in managing illness. The burden impacts physical, emotional, spiritual, and social health. objective this study was to identify among with advanced cancer, associated factors. Materials Methods: Caregivers were randomly interviewed from March-September 2012. Information on baseline characteristics caregiver using the Zarit Burden Inventory (ZBI) collected. Descriptive statistics used analyze data, univariate multiple linear...
BackgroundUnderstanding the perceptions regarding what constitutes a "good death" among cancer patients and their families could help healthcare teams to ensure proper palliative supportive care.ObjectivesTo demonstrate compare wishes of relatives end-of-life care, identify factors associated with patients' preferences place death.MethodsA sample who attended Srinagarind Hospital (Thailand) oncology clinic or day chemotherapy from September 2017 August 2018 were enrolled. Questionnaires...
Low skeletal muscle mass is frequently observed in cancer patients and known to be a poor prognostic factor for survival outcomes. The purposes of our study were determine the prevalence sarcopenia its relation mortality biliary tract cancer. Body composition measurements (skeletal index, total fat mass, bone mineral content) evaluated by using dual-energy x-ray absorptiometry 75 before chemotherapy. Muscle strength was measured handgrip gait speed. Overall associated factors determined....
Obstructive sleep apnea (OSA) is a common factor associated with hypertensive crises. There limited evidence of prevalence and risk factors OSA in emergency.This study recruited adult patients who diagnosed as emergency tested for OSA. The period was between July 2019 January 2020. were categorized non-OSA groups by the from polysomnography. Prevalence executed.During study, there 52 eligible patients. Of those, 30 (57.69%) stepwise logistic regression analysis predicting had two remaining...
The analysis of cfDNA has been applied as a liquid biopsy in several malignancies. However, its value the diagnosis and prognosis cholangiocarcinoma (CCA) have not well defined. We aimed to investigate diagnostic prognostic values level tumor-specific mutation circulating DNA (ctDNA) CCA. plasma levels from 62 CCA patients, 33 benign biliary disease (BBD) patients 30 normal controls were quantified by fluorescent assay. Targeted probe-based sequencing 60 genes was for profiling 10 ctDNA...
Motorcycles are the most common type of vehicle involved in traffic deaths developing countries. Although helmets can provide protection against injury, there is limited evidence available regarding which helmet best protects head and neck injuries this setting. This review was conducted based on articles PubMed, Scopus, Web Science databases. We compared full-face with other types regard to injury prevention road accidents involving motorcyclists. Of 702 studies, six were eligible a total...
PURPOSE Atezolizumab plus bevacizumab treatment is a first-line therapy for unresectable hepatocellular carcinoma (HCC) worldwide. The efficacy, safety, and patient-reported outcomes (PROs) of HCC in Thailand have not yet been reported. This study aimed to evaluate the PROs atezolizumab bevacizumab. MATERIALS AND METHODS From September 2020 August 2021, 30 patients with who met inclusion criteria as were enrolled. Analysis was assessed progression-free survival, overall adverse events (AEs),...
Brain metastasis from cholangiocarcinoma (CCA) is a rare but fatal event. To the best of our knowledge, only few cases have been reported. Herein, we report incident rate and first case series brain metastases CCA.Between January 2006 December 2010 5,164 patients were treated at Srinagarind hospital, Khon Kaen University; those, 8 developed metastasis. Here reviewed clinical data survival times.The CCA was 0.15%. The median age 60 years. Tumor subtypes intrahepatic in 6 hilar 2 patients. All...
Cholangiocarcinoma is an aggressive tumor of the hepatic biliary system and it commonly spreads to regional lymph nodes, liver lungs. However, bone metastasis from cholangiocarcinoma rare compared with other tumors. We herein present case a 61‑year‑old Asian woman who presented pain in right scapular area. Magnetic resonance imaging revealed destruction adjacent soft tissue mass at scapula. The findings on computed tomography were compatible cholangiocarcinoma. Bone biopsy was performed...
This paper reports that surface treatment with CaCl 2 enhances the bioactivity of a calcined kaolin geopolymer.Calcined kaolin, NaOH solution, sodium silicate and heat curing were used to form geopolymer pastes.A soaked-treatment method was applied samples using solution as ion exchange agent.The material determined by simulated body fluid (SBF) in vitro testing method.Scanning electron microscope images showed dense apatite formation on treated after SBF immersion for only 3 days.The...
The northeast has the lowest incidence of breast cancer all regions in Thailand, although national rates are increasing. heterogeneity subnational trends necessitates a comprehensive evaluation and projections to provide evidence for future region-specific strategies that may be employed attenuate this growing burden.Joinpoint regression age-period-cohort modeling were used describe from 1988-2012. Data was projected three separate models range estimates year 2030 by age...
Few studies exist regarding the perception of medical students toward older adults' wishes during their end-of-life period. Better understanding students' perceptions this topic could help improve palliative education. The purposes study were to examine what constitutes a "good death" and demonstrate factors associated with necessary care decisions in patients. This is cross-sectional study. A questionnaire was developed given all at two schools Thailand (Siriraj Srinagarind Hospital) from...