A5005312700- Olfactory and Sensory Function Studies
- Neuroscience and Neuropharmacology Research
- Biochemical Analysis and Sensing Techniques
- Neuroendocrine regulation and behavior
- Circadian rhythm and melatonin
- Biological and pharmacological studies of plants
- GABA and Rice Research
- Neurobiology and Insect Physiology Research
- Multisensory perception and integration
- Advanced Chemical Sensor Technologies
The Francis Crick Institute
2024
University of Regensburg
2018-2020
Our perception of the world depends on brain's ability to integrate information from multiple senses, with temporal disparities providing a critical cue for binding or segregating cross-modal signals. The superior colliculus (SC) is key site integrating sensory modalities, but how cellular and network mechanisms in distinct anatomical regions within SC contribute multisensory integration remains poorly understood. Here, we recorded responses over 5,000 neurons across SC's axes awake mice...
Presenting visual stimuli in neuroscience experiments often requires the combination of analogue signals that carry information about cue presented on LCD display. Such are sensed by photodetectors and recorded to digital converter (ADC) acquisition boards. The use open-source programming languages such as Bonsai is becoming more popular. They used with other hardware Arduino development These microcontroller-based boards can be automate behavioural experiments: e.g., actuate valves motors...
In the rodent olfactory bulb smooth dendrites of principal glutamatergic mitral cells (MCs) form reciprocal dendrodendritic synapses with large spines on GABAergic granule (GC), where unitary release glutamate can trigger postsynaptic local activation voltage-gated Na + -channels (Na v s), that is a spine spike. Can such single MC input evoke release? We find unitary-like via two-photon uncaging causes GC to GABA both synchronously and asynchronously onto dendrites. This indeed requires s...
Abstract In the rodent olfactory bulb smooth dendrites of principal glutamatergic mitral cells (MCs) form reciprocal dendrodendritic synapses with large spines on GABAergic granule (GC), where unitary release glutamate can trigger postsynaptic local activation voltage-gated Na + -channels (Na v s), i.e. a spine spike. Can such single MC input evoke release? We find that unitary-like via two-photon uncaging causes GC to GABA both synchronously and asynchronously onto dendrites. This indeed...
Abstract Vasopressin (VP) is essential for social memory already at the level of olfactory bulb (OB), and OB VP cells are activated by interaction. However, it remains unclear how modulates processing to enable enhanced discrimination very similar odors, e.g., rat body odors. So far, has been shown that reduces firing rates in mitral (MCs) during odor presentation in-vivo decreases amplitudes nerve-evoked excitatory postsynaptic potentials (ON-evoked EPSPs) external tufted in-vitro . We...
Vasopressin (VP) plays a crucial role in social memory even at the level of olfactory bulb (OB), where OB VP cells are activated during interactions. However, it remains unclear how modulates processing to enable enhanced discrimination very similar odors, e.g., rat body odors. Thus far, has been shown that reduces firing rates mitral (MCs) odor presentation vivo and decreases amplitudes nerve-evoked excitatory postsynaptic potentials (ON-evoked EPSPs) external tufted vitro . We performed...