- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Bone and Joint Diseases
- Lymphoma Diagnosis and Treatment
- Periodontal Regeneration and Treatments
- Bariatric Surgery and Outcomes
- Hematological disorders and diagnostics
- Eosinophilic Disorders and Syndromes
- Adipokines, Inflammation, and Metabolic Diseases
- Biomarkers in Disease Mechanisms
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Lung Cancer Treatments and Mutations
- CNS Lymphoma Diagnosis and Treatment
- Sexual function and dysfunction studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Parathyroid Disorders and Treatments
- Inflammation biomarkers and pathways
- Lipid metabolism and disorders
- Systemic Lupus Erythematosus Research
- Genital Health and Disease
- Neuroblastoma Research and Treatments
- Vasculitis and related conditions
- Gastroesophageal reflux and treatments
Istanbul University-Cerrahpaşa
2020-2024
Ankara University
2008-2024
Bezmiâlem Vakıf Üniversitesi
2014-2019
University College London
2012
Background: Endocan is a newly identified proteoglycan released from endothelium, stimulating angiogenesis and when increased, indicates endothelial activation (inflammation). Our aim was to examine the association between serum endocan levels urine albumin–creatinine ratio (UACR).Method: One hundred thirty-seven patients with type 2 diabetes mellitus normal creatinine who had no co-morbidities other than hypertension, diabetic nephropathy, retinopathy, or neuropathy were divided into...
Obesity is an epidemic and its prevalence number of patients underwent bariatric surgery continue to increase worldwide. This study aimed evaluate endoscopic findings co-morbidities, investigate the Helicobacter pylori (H. pylori) infection relationship between body mass index (BMI) gastroesophageal sphincter incompetency in obese patients.An upper gastrointestinal system endoscopy mucosal sampling were performed all hospitalized for surgery. Age, gender, BMI, co-morbidities recorded....
Positron emission tomography and computed (PET/CT) has become an important part of staging treatment evaluation algorithms lymphoma. We aimed to compare the results PET/CT with bone marrow biopsy (BMB) respect involvement (BMI) in patients Hodgkin's lymphoma (HL) aggressive non-Hodgkin's (aNHL).The medical files a total 297 diagnosed HL or aNHL followed at hematology clinics 3 major hospitals İstanbul between 2008 2012 were screened retrospectively 161 classical included study. The referred...
Amaç: Esansiyel trombositoz, trombositlerde ciddi artış ve fonksiyon bozukluğuna sebep olan kök hücre kökenli nadir bir hastalıktır. Trombositlerin fonksiyonlarındaki bozulma artan aktiviteleri sonucunda, yapılarında bulunan granüllerden özgün moleküller salgılanmaktadır. trombositozda görülen hiperkalsemi, sayıca trombositlerden kalsiyum salgılanmasına bağlıdır. Ayrıca, esansiyel trombositoz hastalarında serum fosfor düzeyi pıhtılaşma sırasında içinden dışına salınmasıyla ilişkili olabilir....
Objective This study was conducted with the aim of making contribution to a decision for treatment and determination modalities in patients diagnosed non-Hodgkın lymphoma which increasingly become widespread geriatric population. Materials methods Ninety-one aged over 65 years treated Bezmialem Vakıf University Medical Faculty Hospital Haseki Training Research between 2008 2013 were retrospectively evaluated. Finally, 63 whom data could be reached included study. Results Examining results,...
Monoclonal B-cell lymphocytosis is accepted as an important risk factor for developing familial chronic lymphocytic leukemia (CLL) but does not meet the criteria lymphoproliferative disease, and patients with <5,000 (but 0) CLL-phenotype lymphocytes per mm³.Individuals who have relatives diagnosed CLL should undergo flow cytometry early diagnosis.In our study, a 56-year-old patient's brother had been lymphocytosis, patient was class 1-2 after 2 years.We emphasize that individuals having...
Objective: This study aimed to identify the optimal centrifugal speed for preparation of platelet-rich plasma (PRP) with PRPBAG®, a novel multi-bag system.Methods: The included 120 (60 women and 60 men) clinically healthy volunteers aged 18-35 years.Participants were divided into three age-sex matched groups according centrifugation speeds as follows: 1600 rpm (n=40), 1800 (n=40) or 2000 (n=40).Whole blood (150 mL) was drawn from volunteers, performed 10 minutes.After first spin,...
Objective: This study investigated how vildagliptin (a di-peptidyl peptidase 4 inhibitor) affects portal vein pressure and hepatosteatosis in patients with type 2 diabetes mellitus.Methods: cross-sectional evaluated the use of specific drugs for at least 3 months on two groups mellitus cases.Group 1 used metformin gliclazide, Group same amounts addition vildagliptin.Using Doppler ultrasound, all cases were measured flow velocity, diameter.Degree was also recorded.Results: A total 97...
Diffüz alveoler hemoraji, Sistemik Lupus Eritematozus (SLE) tanılı hastalarda nadir görülen ve katastrofik seyir gösteren bir klinik süreçtir.Olguda lupus nefriti tanısı ile takip edilirken diffüz hemoraji gelişen hasta anlatıldı.Ani nefes darlığı hastaneye başvuran hastada akut solunum yetmezliği böbrek bulguları alevlenmesi olarak değerlendirildi.Pulse metilprednizolon, immunsüpresan tedavi intravenöz immunglobulin tedavisine rağmen iyileşme görül-
Introduction:The aim of this study is demonstrating the sterility PRPBAG®, a multi-bag completely closed PRP preparation system different than kits in market and determining preservability produced with PRPBAG® up to 5 days similar other platelet products.Methods: We recruited 60 participants for increased statistical significance.150 mL whole blood was collected specially PRPBAG®.A double-spin method used samples refrigerated centrifuge manufactured PRPBAG®.We started centrifugation within...
In Chronic Myeloid Leukemia (CML), BCR-ABL fusion gene produces a chimeric tyrosine kinase which activity enhances the proliferation, uncontrolled cell growth, genomic instability and protection of DNA-damaged cells from apoptosis [1]. The inhibitor Imatinib has successfully been introduced in treatment CML. However, many patients develop resistance against Imatinib, is often associated with mutations BCR/ABL [2]. Epidemiological studies have shown consumption whole grain their products...
down, thus increases its plasma concentration.Although these DPP-4 inhibitors act primarily on the pancreatic gland, they also exert effects non-pancreatic organs (1,2).The gastrointestinal system in particular, as well central nervous system, bone, fatty tissue and cardiovascular are most affected (3,4).This includes portal vein (PV) pressure hepatic steatosis.In dog cell culture studies, there is an increased nitric ABSTRACT