A5101494450- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- Inflammatory Biomarkers in Disease Prognosis
- Adipokines, Inflammation, and Metabolic Diseases
- Restless Legs Syndrome Research
- Systemic Sclerosis and Related Diseases
- Glycogen Storage Diseases and Myoclonus
- Renal function and acid-base balance
- Pancreatitis Pathology and Treatment
- Educational Methods and Analysis
- Adipose Tissue and Metabolism
- Genetic and Kidney Cyst Diseases
- Curcumin's Biomedical Applications
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Epilepsy research and treatment
- Pomegranate: compositions and health benefits
- Gynecological conditions and treatments
- Inflammation biomarkers and pathways
- Hemoglobinopathies and Related Disorders
- Sesame and Sesamin Research
- Cleft Lip and Palate Research
- Cerebrovascular and genetic disorders
- Vitamin C and Antioxidants Research
Ankara University
2025
Cukurova University
2025
Kent Hastanesi
2020-2024
Acıbadem Adana Hospital
2020-2024
Acıbadem University
2024
Sağlık Bilimleri Üniversitesi
2023
Bezmiâlem Vakıf Üniversitesi
2014-2019
Tokat Gaziosmanpaşa Üniversitesi
2019
Yedikule Teaching Hospital
2016
Okmeydanı Eğitim ve Araştırma Hastanesi
2016
Type 2 diabetes mellitus is a major global public health burden. A complex metabolic disease, type affects multiple different tissues, demanding "systems medicine" approach to biomarker and novel diagnostic discovery, not mention data integration across omics-es. In the present study, transcriptomics from tissues including beta-cells, pancreatic islets, arterial tissue, peripheral blood mononuclear cells, liver, skeletal muscle of 228 samples were integrated with protein–protein interaction...
BACKGROUND:Childhood obesity characterized by excessive fat in the body is one of most serious health problems worldwide due to social, medical, and physiological complications. Obesity associated diseases are triggering factors for oxidative stress inflammation. The aim this study was explore possible association between childhood inflammatory status. MATERIAL AND METHODS:Thirty-seven obese children 37 healthy controls selected from among admitted BLIND University Paediatrics Department...
Recent technical developments have focused on the full automation of urinalyses, however manual microscopic analysis urine sediment is considered reference method. The aim this study was to compare performances LabUMat-UriSed and H800-FUS100 with microscopy, each other.The sediments 332 samples were examined by these two devices (LabUMat-UriSed, H800-FUS100) microscopy.The reproducibility analyzers, UriSed Fus100 (4.1-28.5% 4.7-21.2%, respectively), better than that microscopy (8.5-33.3%)....
Thalassemia is a chronic disease that significantly affects both children and their families physically, psychosocially economically. Earthquakes are known to disrupt community living standards, cause serious health problems deaths, have greater impact on the of with diseases caregivers. It important reveal experiences specific in order improve post-earthquake care support processes. To explore traumatized mothers caring for Beta-Thalassemia after earthquake expectations from nurses. This...
Bisphenol A (BPA) is known as an endocrine disruptor and it supposed to have a role on the development of central precocious puberty (CPP). Kisspeptin, hypothalamic peptide, neuromodulator gonadotropin releasing hormone has important regulation onset puberty. The BPA levels in girls with CPP premature thelarche (PT) its relation kisspeptin were investigated.Twenty-eight CPP, 28 PT 22 prepubertal control group enrolled study. Urinary serum compared groups. Bivariate correlations performed...
Background: Endocan is a newly identified proteoglycan released from endothelium, stimulating angiogenesis and when increased, indicates endothelial activation (inflammation). Our aim was to examine the association between serum endocan levels urine albumin–creatinine ratio (UACR).Method: One hundred thirty-seven patients with type 2 diabetes mellitus normal creatinine who had no co-morbidities other than hypertension, diabetic nephropathy, retinopathy, or neuropathy were divided into...
The aim of this study is to evaluate the association between seven important H . pylori virulence factors and antibiotic resistance in patients with gastritis. strains isolated from 33 gastritis were examined. Antimicrobial susceptibilities tested by GenoType® HelicoDR (Hain Life Science, Germany) test kit RT-PCR. virulence-factors determined using conventional PCR. 39% resistant for clarithromycin 27% fluoroquinolone. 15% both vacA m1/s2 genotype was most frequent allelic combination....
In this study, we aimed to examine the impact of fasting during month Ramadan on autosomal dominant polycystic kidney disease (-ADPKD) patients with normal near-normal glomerular filtration rate (GFR).This was a prospective observational study ADPKD, majority whom had or GFR. Patients were divided into two groups: group (FG) and nonfasting (NFG). Assessments in NFG performed 1 week before after Ramadan, while FG assessed last day addition abovementioned visits. The following parameters...
Burnout syndrome is recognized as a major global problem among emergency healthcare workers it causes prevalent fatigue, job separations, and disappointment. The objective of this study was to investigate the relationship glial marker S100B in sera physicians with burnout depression.This prospective observational medicine residents three distinct university-based departments medicine. levels were measured before after shifts. In addition, resident completed Maslach Inventory (MBI) Beck...
Endocan is a recently introduced marker of endothelial dysfunction. The objective this study was to compare serum endocan levels in patients with restless legs syndrome (RLS) and control subjects order elucidate whether RLS associated dysfunction.A total 31 drug naïve female age- BMI-matched women were included the study. Patients pathological or physiological conditions history medication use that could potentially influence functions excluded, as well those alcohol abuse history. two...
Acute pancreatitis (AP) is a life-threatening disease with rising incidence. The aim of this study was to investigate the association between oxidative status, lymphocyte deoxyribonucleic acid (DNA) damage, and acute pancreatitis.A total 45 patients AP 35 healthy controls were included in study. We assessed pancreatic enzymes, stress, DNA damage. severity determined by Harmless Pancreatitis Score (HAPS) Balthazar scoring systems.In patients, damage significantly higher than [49.84±25.48...
<h3>Objective:</h3> To investigate bone resorption and formation markers as well mineral density in women with restless legs syndrome (RLS). <h3>Methods:</h3> This was a prospective cross-sectional case-control study involving drug-naive RLS age- body mass index (BMI)–matched female controls. Routine blood analyses, of formation, procollagen 1 n-terminal peptide, resorption, c-telopeptide type collagen (CTX), sclerostin, (BMD) were compared between the 2 groups. Pregnant or breastfeeding...
Introduction: Population of the disabled is increasing worldwide and face with many limitations due to various social physical obstacles. It important that practices are made in order provide ideal health care service for compliance current legislation attitudes personnel positive. The present study aims at determining awareness physicians nurses a university hospital about applications their towards disabled. Method: This cross-sectional was completed 220 participants Kahramanmaraş Sütçü...
Introduction . All findings of preeclampsia appear as the clinical consequences diffuse endothelial dysfunction. Soluble tumor necrosis factor-like weak inducer apoptosis (sTWEAK) was recently introduced a TNF related cytokine in various inflammatory and noninflammatory disorders. sTWEAK found to be dysfunction patients with chronic kidney disease. In our study we aimed compare levels women corresponding healthy pregnant control group. Materials Methods The undertaken 33 normal women....
Vaspin and lipocalin-2 are less-known recent members of adipocytokine family. There ongoing studies investigating the role vaspin ve in metabolic syndrome (MS). Obstructive sleep apnea (OSAS) is independently associated with an increased prevalence MS. We aimed to measure levels which secreted from adipocytes patients severe OSAS examine relationship between these two adipocytokines OSAS.THE STUDY CONSISTED OF TWO GROUPS: apnea-hypopnea index (AHI) >30/h (OSAS group, 34 subjects) age-matched...
We investigated whether pomegranate extract plays a protective antioxidant role against mesenteric ischemia-reperfusion injury (IR), which can lead to systemic response and damage distant organs, such as the lung, liver, kidney.Forty female Wistar-Albino rats were separated into four groups: laparotomy, laparotomy + PG, IR, IR (IR PG). In PG groups, (225 mg/kg) was given by oral gavage at beginning of study. Ischemia induced for 30 minutes, reperfusion subsequently allowed 60 minutes in...
Background and purpose - Burning mouth syndrome is a chronic persistent painful condition characterized by burning sensation in the oral mucosa. We investigated etiological factors of patients presented with history who admitted our outpatient clinics over 8-years period had no underlying identifiable local factors. also tried to determine their demographic clinical characteristics. Our aim was investigate association between psychiatric disorders such as depression anxiety, diseases like...