- Renal Diseases and Glomerulopathies
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Autoimmune Bullous Skin Diseases
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Erythropoietin and Anemia Treatment
- Apelin-related biomedical research
- Iron Metabolism and Disorders
- Parathyroid Disorders and Treatments
- Hormonal Regulation and Hypertension
- Systemic Lupus Erythematosus Research
- Pregnancy and preeclampsia studies
- Hemoglobinopathies and Related Disorders
- Liver Disease Diagnosis and Treatment
- Platelet Disorders and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Diagnosis and treatment of tuberculosis
- Hemodynamic Monitoring and Therapy
- Peripheral Artery Disease Management
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Case Reports on Hematomas
- Tuberculosis Research and Epidemiology
- Biomarkers in Disease Mechanisms
Istanbul Medipol University
2016-2024
Haseki Eğitim ve Araştırma Hastanesi
2011-2020
Sağlık Bilimleri Üniversitesi
2020
Bezmiâlem Vakıf Üniversitesi
2015-2016
Creative Research Enterprises (United States)
2016
Okmeydanı Eğitim ve Araştırma Hastanesi
2014-2015
Istanbul University
2010-2014
Serum alanine aminotransferase (ALT) is a controversial marker for disease monitoring in hepatitis B e antigen (HBeAg)-negative chronic (CHB) patients. The aim of this study was to determine the fibrosis stage and histological activity index (HAI) HBeAg-negative CHB patients with persistently normal ALT (PNALT) high serum HBV DNA (≥2000 IU/ml) investigate clinical risk factors requirement treatment through examination liver biopsy specimens.HBeAg-negative PNALT (≤40 IU/l) were included. HAI...
Abstract Background The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from databases countries or centers. Here, we present extended results Primary Glomerular Diseases Study Turkish Society Nephrology (TSN-GOLD) Working Group. Methods Data patients who underwent renal biopsy and received diagnosis PGD were recorded in database prepared for study. A total 4399 47 centers evaluated between May 2009 2019. at time kidney analyzed. After exclusion without...
Aims. Vascular access is of prime importance for hemodialysis patients. We aimed to study early complications catheters placed in different central veins patients with acute or chronic renal failure without ultrasound (US ) guidance. Material and Methods. Patients who were admitted our unit between March 2008 December 2010 need vascular have been included. 908 examined their demographic parameters, primary disease, indication catheterization, type location the catheter, implantation...
Abstract The data regarding primary FSGS (pFSGS) from different parts of the world differ. While prevalence pFSGS has been increasing in Western countries like USA, it follows an inconsistent trend Europe and Asia a decreasing Far Eastern such as China last two decades. There are undetermined factors to explain those national geographic discrepancies. Herein, we aimed reveal current with clinical histopathological characteristics Turkish adults. This study includes biopsy-proven patients...
Abstract Anti‐neutrophilic cytoplasmic antibody (ANCA) positivity is seen in some systemic necrotizing vasculitides. Wegener's granulomatosis and microscopic polyangiitis are among the ANCA‐associated vasculitides (AASV) mortality very high when renal failure occurs together with alveolar hemorrhage. The role of plasmapheresis treatment these diseases has been studied retrospectively. Twelve patients AASV who had immunosuppressive medications have involved. Primary diseases, protocols,...
Abstract Background Many markers have been proposed for CVD risk assessment in dialysis population. Apelin is a peptide that has roles cardiovascular functions and volume regulation namely vasodilation, decreased blood pressure (BP), positive inotropic effect inhibition of antidiuretic hormone release. The aim this study was to examine relationship apelin levels with echocardiographic findings laboratory parameters related function bone mineral metabolism among peritoneal (PD) patients....
Introduction: Hepcidin, a small peptide hormone synthesized in the liver, plays central role regulation of iron metabolism. Hepcidin generation chronic kidney disease (CKD) is dependent on status, anemia, inflammation, and hypoxia erythropoietin levels. In our study, relationship between Prohepcidin levels inflammation indices non-diabetic uremic patients was investigated. Methods: This study has cross-sectional design which includes four groups: Non-diabetic 21 with stage 4 CKD...
Vaspin, a recently identified adipokine, is visceral adipose tissue-derived serine protease inhibitor that may have insulin sensitizing effect on tissue. Herein, we measured vaspin level in patients with different stages of diabetic nephropathy (DNP), and investigated the correlation other inflammatory parameters. 106 adult type 2 no known chronic disease were included grouped according to stage DNP: Albuminuria <30 mg/day estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73m(2)...
Introduction . All findings of preeclampsia appear as the clinical consequences diffuse endothelial dysfunction. Soluble tumor necrosis factor-like weak inducer apoptosis (sTWEAK) was recently introduced a TNF related cytokine in various inflammatory and noninflammatory disorders. sTWEAK found to be dysfunction patients with chronic kidney disease. In our study we aimed compare levels women corresponding healthy pregnant control group. Materials Methods The undertaken 33 normal women....
AIM:To examine all skin changes in peritoneal dialysis (PD) patients followed up our unit. METHODS:Patients on PD program for at least three months without any known chronic disease were included the study.Patients with already diagnosed disease, those who have systemic diseases that may cause lesions, malignancies and did not give informed consent excluded from study.All examined by same predetermined dermatologist findings recorded.The demographic, clinical laboratory data including...
Klippel Trenaunay Weber syndrome (KTWS) is a rare disease characterized by hemihypertrophy, variceal enlargement of the veins, and arteriovenous (AV) malformations. Renal involvement in KTWS not known except case reports. Herein, we present with nephrotic syndrome. A 52-year-old male was admitted due to dyspnea swelling body for last three months. The pathological physical findings were diffuse edema, decreased lung sounds at right basal site, increased diameter length left leg compared one,...
One of the main factors determining survival peritoneal dialysis (PD) patients is volume status. We aimed to investigate hydration status PD by bio-impedance spectroscopy (BIS) and echocardiography study relation them with apelin, which has effects related like vasodilation, positive inotropism, inhibition ADH release RAS antagonism. Chronic without active cardiac disease or clinically prominent hypervolemia were included. Besides demographic, clinical, laboratory data, BIS echocardiographic...
Cyclic thrombocytopenia (CTP) is a rare disorder characterized by periodic decreases and increases in platelet levels. Each cycle usually spans period of 3-5 weeks. Clinical features are similar to those idiopathic thrombocytopenic purpura (ITP), so patients frequently misdiagnosed as having ITP. However, CTP does not respond most treatments used ITP such corticosteroids, splenectomy intravenous immunoglobulin. In this case report, we present 33-year-old woman with Siklik trombositopeni (ST)...
Hypoparathyroidism is the most common cause of symmetric calcification basal ganglia. Herein, a case primary hypoparathyroidism with severe tetany, rhabdomyolysis, and acute kidney injury presented. A 26-year-old male was admitted to emergency clinic leg pain cramps, nausea, vomiting, decreased amount urine. He had been treated for epilepsy last 10 years. department pain, cramping in hands legs, agitation multiple times within six months. prescribed antidepressant antipsychotic medications....