A5016489026- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- Organ Transplantation Techniques and Outcomes
- Renal and Vascular Pathologies
- Organ Donation and Transplantation
- Polyomavirus and related diseases
- Dialysis and Renal Disease Management
- COVID-19 Clinical Research Studies
- Complement system in diseases
- Pregnancy and Medication Impact
- Transplantation: Methods and Outcomes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pharmacological Effects and Toxicity Studies
- Cytomegalovirus and herpesvirus research
- Blood groups and transfusion
- Chronic Kidney Disease and Diabetes
- Vasculitis and related conditions
- Systemic Sclerosis and Related Diseases
- Viral-associated cancers and disorders
- Long-Term Effects of COVID-19
- Electrolyte and hormonal disorders
- COVID-19 and healthcare impacts
- Pneumocystis jirovecii pneumonia detection and treatment
- Neurological Complications and Syndromes
- SARS-CoV-2 and COVID-19 Research
Istanbul University
2016-2025
Koç University
2020-2023
Turkish Society of Hematology
2023
Istanbul Medipol University
2016
Memorial Hospital of South Bend
2015
Istanbul Memorial Hospital
2013
SSK İhtisas Hastanesi
2008
Renal Association
2007
Southmead Hospital
2007
Hospital de Santa Maria
2007
There is a need to define regions of gene activation or repression that control human kidney cells in states health, injury, and repair understand the molecular pathogenesis disease design therapeutic strategies. Comprehensive integration expression with epigenetic features regulatory elements remains significant challenge. We measure dual single nucleus RNA chromatin accessibility, DNA methylation, H3K27ac, H3K4me1, H3K4me3, H3K27me3 histone modifications decipher landscape regulation...
Hyperkalemia is a major cause of mortality in the patients who suffer from crush syndrome aftermath earthquakes. The aim this study to investigate frequency and effects hyperkalemia 639 victims catastrophic Marmara earthquake that struck northwestern Turkey, August 1999.Within first week disaster, questionnaires were sent 35 reference hospitals treated victims. Information on serum potassium which was provided 595 out submitted analysis.In admitted within 3 days disaster (n = 401) 5.4 +/-...
Coronavirus Disease 2019 (COVID-19) is currently a pandemic with mortality rate of 1%-6% in the general population. However, seems to be significantly higher elderly patients, especially those hospitalized comorbidities, such as hypertension, diabetes, or coronary artery diseases. Because viral diseases may have atypical presentations immunosuppressed course disease transplant patient population unknown. Hence, management these patients COVID-19 an area interest, and unique approach...
Abstract Introduction Management of COVID‐19 in kidney transplant recipients should include treatment the infection, regulation immunosuppression, and supportive therapy. However, there is no consensus on this issue yet. This study aimed to our experiences with diagnosed COVID‐19. Material Methods Kidney from five major centers Istanbul, Turkey, were included retrospective cohort study. Patients classified as having moderate or severe pneumonia for analysis. The primary endpoint was...
Abstract Background Kidney transplant recipients have an increased risk of complications from COVID-19. However, data on the allograft damage or death in kidney recovering COVID-19 is limited. In addition, first and second waves pandemic occurred at different times all over world. Turkey, Health Minister confirmed case March 2020; after that, wave between August afterward, began September 2020. This study aims to demonstrate clinical presentations two Turkey explore impact outcomes initial...
Coronavirus Disease-19 (COVID-19) has high mortality in kidney transplant recipients (KTR), and vaccination against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is vital for this population. Although the humoral response to messenger RNA vaccines was shown be impaired KTR, there a lack of data regarding antibody inactivated vaccines. We investigated two consequent doses SARS-CoV-2 vaccine (CoronaVac; Sinovac Biotech, China).
Abstract: Endothelial dysfunction is of vital importance, as it may cause ischemia and in various organs. Despite, this problem has been well documented patients with end‐stage renal disease (ESRD), there not enough data considering issue following transplantation. One the potential causes endothelial transplant recipients be administration calcineurin inhibitors. The aim study to evaluate effects two different inhibitors [cyclosporin A (CsA) tacrolimus (FK506)] on function patients....
In Brief Background Mammalian target of rapamycin inhibitors may confer cardioprotective advantages, but clinical data are limited. Methods the open-label ELEVATE trial, kidney transplant patients were randomized at 10 to 14 weeks after convert from calcineurin inhibitor (CNI) everolimus or remain on standard CNI therapy. Prespecified end points included left ventricular mass index and, in a subpopulation patients, arterial stiffness as measured by pulse wave velocity. Results The mean...
Proteinuria, developing after renal transplantation may influence allograft and patient outcomes. This study aimed to investigate the effect of proteinuria on survival. Among 514 patients, 56 (11%) patients with good function were evaluated retrospectively. Patients classified as group P (20 permanent proteinuria, Male/Female: 16/4) T (36 temporary M/F: 29/7) according type proteinuria. Also, considering amount M (32 massive 29/3) NM (24 non‐massive 16/8). The mean time interval between...
Autonomic dysfunction in hemodialysis patients is one of the components uremic neuropathy. In this prospective study, we investigated effect renal transplantation on autonomic with long-term time-domain and frequency-domain heart rate variability. Fourteen (10 male, 4 female; mean age 33 ± 11 (range 16–50) years) were examined before at early after period (mean 4.6 1.5 3–7.5) months). The time spent was 16.7 15.6 6–65) months. analysis, significant increases all parameters except pNN50 (SD,...