A5009981142- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Disease Prevention
- Cardiovascular and Diving-Related Complications
- Mechanical Circulatory Support Devices
- Vascular anomalies and interventions
- Cardiovascular Disease and Adiposity
- Cardiovascular Issues in Pregnancy
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Congenital Diaphragmatic Hernia Studies
- Infective Endocarditis Diagnosis and Management
- Obesity, Physical Activity, Diet
- Cardiac pacing and defibrillation studies
- Blood Pressure and Hypertension Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Conditions and Treatments
- Birth, Development, and Health
- Williams Syndrome Research
- Tracheal and airway disorders
- Renal and Vascular Pathologies
University Hospital of Geneva
2006-2021
University of Geneva
2007-2020
Geneva College
2020
University of Lausanne
2019
Hôpital Necker-Enfants Malades
2001-2010
Université Paris Cité
1997-2010
Assistance Publique – Hôpitaux de Paris
2007-2010
Hôpital des Enfants
2002-2008
Délégation Paris 5
2007
Inserm
2000-2007
Background —Pulmonary regurgitation can lead to severe right ventricular dysfunction, which is a delicate postoperative problem in the long-term follow-up of patients who had surgery for congenital heart diseases. Clinical conditions suffering from pulmonary valve incompetence are improved by replacement with prosthetic valve. To date, surgical approach only option replace We report first experience percutaneous implantation. Methods and Results —A fresh bovine jugular vein containing native...
Atherosclerosis is preceded by a phase of changes in the arterial wall that could have functional consequences even before appearance atheromatous changes. We hypothesized early alterations mechanical properties precede clinical and echographic modifications. used an automatic, computerized, ultrasonic procedure to evaluate geometric characteristics common carotid artery (CCA) normotensive children with primary familial class IIA hypercholesterolemia (FH; n=30; mean+/-SD age, 11+/-2 years...
To determine whether impaired brachial endothelial (flow-mediated dilation, FMD) and smooth muscle function (nitroglycerin-mediated NTGMD), remodelling of the common carotid artery (CCA) develop before puberty in obese children. Arterial intima–media thickness (IMT), FMD NTGMD were measured by high-resolution ultrasound 48 23 lean pre-pubertal children (8.8 ± 1.5 years old). We assessed central pulse pressure, incremental elastic modulus (Einc), casual ambulatory systolic (SBP) diastolic...
The role of antiretroviral therapy in acceleration atherosclerosis HIV-infected adults is controversial, partly because the confounding effects involvement classic cardiovascular risk factors.To study vascular function children.Cross-sectional 49 children (34 receiving and 15 never treated) if 24 age- sex-matched controls.Automatic, computerized, ultrasonic procedure evaluation geometric mechanical properties common carotid artery, endothelium-dependent dilation endothelium-independent...
OBJECTIVE: Concern continues to be expressed about the long-term impact of coronary artery translocation after arterial switch operation for transposition great arteries. This study was conducted determine prevalence obstructions translocated arteries by use selective angiography. METHODS AND RESULTS: 64 children (mean age 7.6 (SD) 1.5 years) who had survived an underwent evaluation. They been operated on one surgeon and they were followed up a single hospital. Selective angiography possible...
Abstract In a consanguineous Pakistani family with two affected individuals, homozygous variant Gly399Val in the eighth transmembrane domain of taurine transporter SLC6A6 was identified resulting hypomorph transporting capacity ~15% compared normal. Three-dimensional modeling this has indicated that it likely causes displacement Tyr138 (TM3) side chain, important for transport taurine. The individuals presented rapidly progressive childhood retinal degeneration, cardiomyopathy and almost...
<h3>Objectives</h3> To establish the prevalence of tricuspid valve abnormalities in children with a double discordant heart (or congenitally corrected transposition great arteries); to study influence loading conditions induced by various surgical interventions on right and left ventricle patients discordance an abnormal valve; propose rational approach. <h3>Methods</h3> Case notes were reviewed 141 consecutive admitted first year life types (intact ventricular septum (group 1), septal...
<h3>OBJECTIVE</h3> To determine whether arterial wall hypertrophy in elastic arteries was associated with alteration their mechanical properties young patients Williams syndrome. <h3>METHODS</h3> Arterial pressure and intima–media thickness, cross sectional compliance, distensibility, circumferential stress, incremental modulus of the common carotid artery were measured non-invasively 21 (mean (SD) age 8.5 (4) years) children similar age. <h3>RESULTS</h3> Systolic diastolic blood pressures...
Background: Transcatheter closure of atrial septal defect (ASD) is an alternative approach to surgery in selected patients. Balloon stretched diameter (BSD) considered as the standard way measuring ASD size. Three‐dimensional transesophageal echocardiography (3D‐TEE) provides views allowing its measurement and identifying spatial relation with neighboring structures. Our aim was compare BSD 3D‐TEE methods measure size before transcatheter closure. Methods Results: Seventy‐six consecutive...