A5042793255- Seaweed-derived Bioactive Compounds
- Skin Protection and Aging
- Phytochemicals and Antioxidant Activities
- Bee Products Chemical Analysis
- Moringa oleifera research and applications
- Wound Healing and Treatments
- Extracellular vesicles in disease
- Fungal Biology and Applications
- Medical and Biological Ozone Research
- Echinoderm biology and ecology
- Advanced Nanomaterials in Catalysis
- Mast cells and histamine
- Free Radicals and Antioxidants
- Exercise and Physiological Responses
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- MicroRNA in disease regulation
- Synthesis and biological activity
- Phytochemistry and Bioactive Compounds
- Genomics, phytochemicals, and oxidative stress
- Food Quality and Safety Studies
- Phytochemical Studies and Bioactivities
- Occupational and environmental lung diseases
- Antimicrobial Peptides and Activities
- Neurobiology and Insect Physiology Research
Chungnam National University
2022-2024
Chonnam National University
2020-2022
Ultraviolet B (UVB) radiation-induced oxidative skin cell damage is a major cause of photoaging. In the present study, low molecular weight fucoidan fraction (SHC4) was obtained from Sargassum horneri by Celluclast-assisted extraction, followed step gradient ethanol precipitation. The protective effect SHC4 investigated in human keratinocytes against UVB-induced stress. purified characterized Fourier-transform infrared spectroscopy (FTIR), 1H nuclear magnetic resonance (NMR), agarose...
The present study discloses the identification of phenolic compounds in Moringa oleifera hot water extract (MOH) and evaluation its antioxidant activity on H2O2-induced oxidative stress Vero cells. Upon analysis, MOH was found to contain indicated 2,2-diphenyl-1-picrylhydrazyl (DPPH) 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS+) radical scavenging with IC50 values 102.52 122.55 µg/mL, respectively. ferric reducing power (FRAP) a dose-dependent increase...
The emergence of fine dust (FD) among air pollutants has taken a toll during the past few decades, and it provided both controversy platform for open conversation amongst world powers finding sustainable solutions effective treatments health issues. present study emphasizes protective effects (-)-loliolide (HTT) isolated from Sargassum horneri against FD-induced oxidative stress in human HaCaT keratinocytes. purification was carried out by centrifugal partition chromatography. HTT did not...
The present study investigated the protective effects of Sargassum horneri (S. horneri) ethanol extract (SHE) against atopic dermatitis (AD), known as an abnormal immune response in house dust mite (HDM)/2,4-dinitrochlorobenzene (DNCB)-stimulated NC/Nga mice. oral administration SHE attenuated AD symptoms, including skin severity, transepidermal water loss (TEWL), and ear edema HDM/DNCB-stimulated Moreover, histological analysis revealed that improved epidermal hyperplasia hyperkeratosis,...
Abstract The present study aimed to evaluate the protective effect of a methanol extract Sargassum horneri (SHM), which contains 6-hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one (HTT) and apo-9′-fucoxanthinone, against ultraviolet B (UVB)-induced cellular damage in human keratinocytes its underlying mechanism. SHM significantly improved cell viability UVB-exposed by reducing generation intracellular reactive oxygen species (ROS). Moreover, inhibited UVB exposure-induced...
Ultraviolet (UV) B exposure is a prominent cause of skin aging and contemporary subject interest. The effects are progressing through the generation reactive oxygen species (ROS) that alter cell signaling pathways related to inflammatory responses. present study evaluates protective (7aR)-6-hydroxy-4,4,7a-trimethyl-6,7-dihydro-5H-1-benzofuran-2-one (HTT) isolated from edible brown algae Sargassum horneri against UVB in human dermal fibroblasts (HDFs). HTT treatment dose-dependently...
Fucoidans exhibit a wide range of bioactivities and receive significant attention in functional food cosmetic research. Industrial applications fucoidan are limited partially due to high extraction purification costs. The present study implements an enzyme-assisted step-gradient ethanol precipitation for fractionating from Sargassum coreanum based on its charge molecular weight evaluation ultraviolet B (UVB) protective effects human keratinocytes (HaCaT). fraction SCOC4 indicated higher...
At present air pollution in parts of East Asia is at an alarming level due to elevated levels fine dust (FD). Other than pulmonary complications, FD was found affect the pathogenesis ROS-dependent inflammatory responses via penetrating barrier-disrupted skin, leading degradation extracellular matrix components through keratinocyte-fibroblast axis. The study discloses evaluation human dermal fibroblast (HDF) preconditioned keratinocyte media (HPM) primed without and with (-)-loliolide (HTT)....
Sasa borealis (Hack.) Makino & Shibata or broad-leaf bamboo is famous for its richness of bioactive natural products and uses in traditional medicine anti-inflammatory, diuretic, antipyretic properties preventive effects against hypertension, arteriosclerosis, cardiovascular disease, cancer. The present study investigated the antioxidant activity S. hot water extract (SBH) ameliorating hydrogen peroxide-induced oxidative stress, using an African green monkey kidney epithelial cell line...