A5021686525- Inflammatory Bowel Disease
- Gut microbiota and health
- Microscopic Colitis
- Eosinophilic Esophagitis
- Autoimmune and Inflammatory Disorders
- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Clostridium difficile and Clostridium perfringens research
- Bacterial biofilms and quorum sensing
- IL-33, ST2, and ILC Pathways
- Diverticular Disease and Complications
- Eosinophilic Disorders and Syndromes
- Psoriasis: Treatment and Pathogenesis
- Diet and metabolism studies
- Sphingolipid Metabolism and Signaling
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Lupus Erythematosus Research
Sorbonne Université
2021-2025
Assistance Publique – Hôpitaux de Paris
2024-2025
Centre de Recherche Saint-Antoine
2021-2025
Hôpital Saint-Antoine
2023-2025
Inserm
2024-2025
Fédération Hospitalo-Universitaire, Paris Center for Microbiome Medicine
2025
Université de Poitiers
2023-2024
Centre Hospitalier Universitaire de Poitiers
2023
Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers
2022
Nantes Université
2022
Abstract Background and Aims Data regarding the effectiveness safety of Janus kinase [JAK] inhibitors sphingosine-1-phosphate [S1P] receptor modulators in antibiotic refractory chronic pouchitis [CARP] are lacking. Methods This ECCO-CONFER project retrospectively collected data for JAK inhibitor or S1P modulator treatments CARP with at least 3 months follow-up. The outcomes included corticosteroid- antibiotic-free clinical response remission 12 months, trends modified disease activity index...
Summary Background Early complicated Crohn's disease (CD) may require ileal resection as first‐line treatment. Aim To evaluate the long‐term outcomes of patients who underwent early resection. Methods We conducted a retrospective study in two inflammatory bowel diseases (IBD) referral centres, including with ileocaecal and segmental within 5 years CD diagnosis. was defined 6 months diagnosis, intermediate between 2 years, late years. The primary outcome cumulative risk second surgery....
Abstract Background Ileocecal resection (ICR) is a common procedure in Crohn’s disease (CD). Increasing evidence suggests ICR may be considered first-line treatment for localized ileal CD to maintain long-term remission, rather than starting biologics. However, removal of the ileocecal valve affects bowel transit and disabling symptoms arise. The aim our study was prospectively assess impact primary on daily digestive patients. Methods We included patients who underwent at Saint-Antoine...
Abstract Background Data regarding effectiveness and safety of JAK inhibitors S1P receptor modulators in chronic antibiotic refractory pouchitis (CARP) are lacking. This ECCO-CONFER project collected cases CARP treated with or modulators. Methods retrospective multicentre study across Europe through the project, including patients ulcerative colitis (UC) diagnosis who underwent proctocolectomy ileal pouch anal anastomosis (IPAA), for at least three months follow up. Main outcomes were...
Intestinal dysbiosis is a key feature in the pathogenesis of inflammatory bowel disease (IBD). Acyl-homoserine lactones (AHL) are bacterial quorum-sensing metabolites that may play role changes host cells-gut microbiota interaction observed during IBD. The objective our study was to investigate presence and expression AHL synthases receptor genes human gut ecosystem We used an silico approach, applied Inflammatory Bowel Disease Multi’omics Database comprising metagenomic metatranscriptomic...
Abstract Background Intestinal dysbiosis is a key feature in the pathogenesis of inflammatory bowel diseases (IBD). Bacterial quorum sensing mediated by acyl-homoserine lactones (AHL) might play role dialogue between gut microbiota and host. The main objective our study was to investigate presence expression AHL synthase receptor genes human ecosystem during IBD. Methods To confirm gut, mass spectrometric detection performed on stool samples from IBD patients non-IBD subjects. Then, an...