A5055623563- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Schizophrenia research and treatment
- Pain Management and Placebo Effect
- Neurological disorders and treatments
- COVID-19 Clinical Research Studies
- Stress Responses and Cortisol
- Pain Mechanisms and Treatments
- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- Epilepsy research and treatment
- Gut microbiota and health
- Infant Nutrition and Health
- Nerve injury and regeneration
- Advanced Proteomics Techniques and Applications
- Diet and metabolism studies
- Neurogenesis and neuroplasticity mechanisms
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cognitive Abilities and Testing
- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Treatment of Major Depression
- Cholesterol and Lipid Metabolism
Ollscoil na Gaillimhe – University of Galway
2025
Massachusetts Institute of Technology
2022-2024
Universidade de Vigo
2019-2023
Servicio Gallego de Salud
2017-2023
Galicia Sur Biomedical Foundation
2019-2023
Centro de Investigación Biomédica en Red de Salud Mental
2017-2021
Centro de Investigación Biomédica en Red
2018-2021
University Hospital Complex Of Vigo
2017-2018
Complexo Hospitalario Universitario A Coruña
2017-2018
Demyelination is a common pathological feature in wide range of diseases, characterized by the loss myelin sheath and myelin-supporting oligodendrocytes. These losses lead to impaired axonal function, increased vulnerability axons damage, result significant brain atrophy neuro-axonal degeneration. Multiple pathomolecular processes contribute neuroinflammation, oligodendrocyte cell death, progressive neuronal dysfunction. In this study, we use cuprizone mouse model demyelination investigate...
Human milk is the biological fluid with highest exosome amount and rich in microRNAs (miRNAs). These are key regulators of gene expression networks both normal physiologic disease contexts, miRNAs can influence many processes have also shown promise as biomarkers for disease. One aspects regeneration nervous system that there practically no molecules be used potential drugs. In first weeks lactation, we know human breast must contain mechanisms to transmit molecular information brain...
Abstract Schizophrenia is a progressive disorder characterized by multiple psychotic relapses. After every relapse, patients may not fully recover, and this lead to loss of functionality. Pharmacological treatment represents key factor minimize the biological, psychological psychosocial impact disorder. The number relapses duration episodes induce potential neuronal damage subsequently, neurodegenerative processes. Thus, comparative study was performed, including forty healthy controls...
Lithium has shown the capacity to: a) inhibit replication of several types viruses, some which are similar to SARS-CoV-2 virus, b) increase immune response by reducing lymphopenia, and c) reduce inflammation preventing or cytokine storm. In present study, we have treated six patients with severe COVID-19 infection lithium carbonate. We found that carbonate significantly reduced plasma reactive C-Protein levels, increased lymphocyte numbers decreased neutrophil-lymphocyte ratio, improving...
Schizophrenia is a chronic, severe and disabling psychiatric disorder with complex neurobiological pathophysiology that translates into an ambiguous aetiology. The lack of consensus regarding the pathogenesis this ailment has increased need to explore new research lines in regard. Advances "omics" sciences, such as proteomics, promotes approaches better understand molecular basis schizophrenia identify potential biomarkers. This makes use proteomics data discover possible analytes associated...
The growth and development of the human brain is a long complex process that requires precise sequence genetic molecular events.
At the beginning of pandemic, we observed that lithium carbonate had a positive effect on recovery severely ill patients with COVID-19. Lithium is able to inhibit replication several types viruses, some which are similar SARS-CoV-2 virus, increase immune response and reduce inflammation by preventing or reducing cytokine storm. Previously, published an article data from six severe COVID-19 infection, where proposed could be used as potential treatment for Now, set out conduct randomized...
Background: Neuropathic pain is defined as initiated or caused by injury disease of the somatosensory system. It a chronic with an extremely high impact on patients quality life, which progressively incapacitating. This paper reviews evidence-based guidelines management neuropathic pain, aiming at establishing specific and targeted recommendations based oral topical drugs available in Portugal.
The neurobiology of schizophrenia is multifactorial, comprising the dysregulation several biochemical pathways and molecules. This research proposes a peripheral biomarker for that involves second extracellular loop norepinephrine transporter (NEText), tropomyosin receptor kinase C (TrkC), neurotrophin-3 (NT-3) in T cells. study NEText, NT-3, TrkC was performed cells plasma extracted from blood 54 patients with healthy controls. Levels TrkC, NET were significantly lower compared to...
Substance-related disorders (SRD) have been consistently associated with alterations both in cognitive and executive functions, which affect to patients’ quality of life. The main objective this work was test the beneficial effects on patients SRD after implementation “Trisquel,” an intervention program board game format. To check effectiveness Trisquel program, a group people diagnosed randomly assigned either experimental or control group. performed structured sessions twice week during 3...