A5057769406- Pharmacological Effects of Natural Compounds
- Genetic and phenotypic traits in livestock
- Seaweed-derived Bioactive Compounds
- Animal Nutrition and Physiology
- Peroxisome Proliferator-Activated Receptors
- Immune Response and Inflammation
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Adipokines, Inflammation, and Metabolic Diseases
- Plant Reproductive Biology
- Phytochemical and Pharmacological Studies
- Echinoderm biology and ecology
- Ginseng Biological Effects and Applications
- Cytokine Signaling Pathways and Interactions
- RNA Research and Splicing
- Chromatography in Natural Products
- Adipose Tissue and Metabolism
- Drug Solubulity and Delivery Systems
- RNA and protein synthesis mechanisms
- Alzheimer's disease research and treatments
- Marine and coastal plant biology
- Inflammation biomarkers and pathways
- Berberine and alkaloids research
Sichuan Cancer Hospital
2025
University of Electronic Science and Technology of China
2025
Shanghai Ocean University
2024
Dalian Ocean University
2024
Dalian University of Technology
2024
Chengdu University of Traditional Chinese Medicine
2023
Jiangsu Yanjiang Chemical Resources Development Research Institute (China)
2022
China University of Geosciences (Beijing)
2021
Shanghai Jiao Tong University
2020
Animal Science Research Institute
2011-2019
This study aimed to obtain a high yield and purity of Sargassum pallidum polyphenol extracts (SPPE) its enzyme activity. Fresh seaweed was selected for optimization ultrasound-assisted extraction (UAE) conditions purification using macroporous resin Sephadex LH20 SPPE. The SPPE characterized UPLC-QTOF-MS/MS α-amylase, α-glucosidase, tyrosinase, AchE inhibitory activity were determined. maximum rate 7.56 mg GAE/g the reached 70.5% after LH-20 purification. A total 50 compounds identified by...
Effective immunotherapeutic treatment of solid tumors has been greatly challenged by the complex hostile tumor immunosuppressive microenvironment (TIME), which typically involves hypoxia and immunosuppression. Herein, a multifunctional biomimetic gold nano-modulator (denoted as GNR-SNO@MMT) was developed to realize efficient second near-infrared (NIR-II) photothermal immunotherapy via targeting deep penetration, vascular normalization immune reprogramming. NIR-II agent nanorods (GNR) were...
This study aimed to investigate the efficacy and safety of echinacoside (ECH) using an osteopenia rat model. Forty-eight 6-month-old female Sprague-Dawley rats were randomly divided into one sham-operated group (SHAM) five OVX (ovariectomized) subgroups: SHAM with vehicle 0.5% carboxymethylcellulose sodium (0.5% CMC-Na) (OVX), 17 β -estradiol (E2), ECH graded doses (ECH-L, ECH-M, ECH-H). The effects E2 on serum biochemical parameters, bone mineral density (BMD), biomechanical properties,...
1. Toll-like receptors (TLRs) are type I transmembrane proteins that play an essential role in the innate immune system. Studies on structure and function of TLRs can be applied to development new approaches control diseases humans animals. 2. A 3432-bp cDNA encoding duck toll-like receptor 4 (duTLR4) was cloned from splenic lymphocytes using RT-PCR rapid amplification ends. 3. The encoded protein, which predicted contain 843 amino acids, had a molecular weight 96·01 kDa included archetypal...
Purpose: This present study investigated the absorption kinetics of echinacoside (ECH) in situ and vitro its oral bioavailability rats. Additional aim was to find an agent(s) promote ECH among two efflux proteins three promoters. Methods: behaviors were by everted gut sac model single-pass intestinal perfusion situ. Pharmacokinetics performed investigate influences verapamil clove oil on vivo. All samples measured at different time intervals high performance liquid chromatography. Results:...
The objective of this study was to estimate genetic parameters for feed efficiency and relevant traits in 2 laying duck breeds, determine the relationship residual intake (RFI) with egg quality traits. Phenotypic records on 3,000 female ducks (1,500 Shaoxing 1,500 Jinyun ducks) from a random mating population were used RFI, conversion ratio (FCR), (FI), BW, BW gain (BWG), mass laid (EML) at 42 46 wk age. heritability estimates EML, FCR, FI, RFI 0.22, 0.19, 0.27 0.14, 0.24, 0.24 ducks,...
Akebia saponin D (ASD) exhibits a variety of pharmacological activities, such as anti-osteoporosis, neuroprotection, hepatoprotection, but has poor oral bioavailability. A self-nanoemulsifying drug delivery system loaded with akebia - phospholipid complex (APC-SNEDDS) (composition: Peceol: Cremophor® EL: Transcutol HP: ASD: phospholipid; ratio: 10:45:45:51:12.3, w:w:w:w:w) was first developed to improve the absorption saponins and it found significantly enhance ASD's bioavailability by 4.3...
Cuscutae Semen (CS) has been prescribed in traditional Chinese medicine (TCM) for millennia as an aging inhibitor, anti-inflammatory agent, a pain reliever, and aphrodisiac. Its three main forms include crude (CCS), wine-processed CS (WCS), stir-frying-processed (SFCS). Premature ovarian insufficiency (POI) is globally occurring medical condition. The present work sought highly efficacious multi-target therapeutic approach against POI with minimal side effects. Finally, it analyzed the...
Abundance of duck adipocyte fatty acid-binding protein (A-FABP) mRNA was detected in this study by quantitative real-time PCR. The results showed that A-FABP gene expressed muscular tissues and many organs, except pancreas, lung, kidney, highly adipose tissues, especially sebum. expression differentiation-related genes upregulated oleic acid, the knockdown suppressed acid-stimulated these cultured adipocytes, indicating might play an important role differentiation.
Ovoinhibitor (OIH) is the main proteinase inhibitor in egg white. In present study, real-time quantitative PCR and Western-Blot were used to analyze different expression pattern of OIH ovaries as a candidate gene reproductive traits Jingjiang ducks (JJ ducks) Shaoxing (SX during three laying stages. To study polymorphism those two duck populations, we designed five pairs primers detect SNPs exon 3-5, 5-6, 14-16 intron 7, 9 by polymerase chain reaction-restriction fragment length (PCR-RFLP)...
1. The aim of this study was to identify the effect perilla extract, a source polyunsaturated fatty acids, on lipid metabolism and expression lipid-related genes in livers Shaoxing ducks. 2. Two hundred forty 28-week-old laying ducks received commercial diet with extract added at 0 (control) or 200 mg/kg feed. 3. Ducks fed had increased rates compared control 4. Serum concentrations triglycerides were reduced by while high-density lipoprotein cholesterol total serum increased. 5. involved...