Nine unsymmetrical azines containing a coumarin moiety were prepared by the reaction of hydrazone 4-hydroxy-3-acetylcoumarin with differently substituted aromatic aldehydes. The fully spectrally characterized, including complete assignment 1 H- and 13 C-NMR resonances, assessed for their acute toxicities in Artemia salina model. Their free radical scavenging activities tested DPPH assay, vitro antimicrobial determined against seven bacterial two fungal strains. p-hydroxyphenyl group shown to...

The content of phytochemicals, total phenolics, flavonoids and antioxidant potential extracts Juniperus communis L. oxycedrus berries were determined. Ethanol, ethyl acetate chloroform used for the process extraction. Phytochemical monitoring was based on already known methods, while in vitro activities done by DPPH assay. screening showed a wide spectrum phytochemicals. Ethanolic extract possesses strongest activity (IC50 = 28.55 ± 0.24 µ/ml), as well higher contents 189.82 0.27 mg gallic...

GC and GC/MS analyses of the diethyl ether ethyl acetate extracts obtained from aerial parts Stachys germanica subsp. heldreichii (Boiss) Hayek, iva Griseb., plumosa Griseb. scardica Balkan peninsula endemics, were performed. One hundred seventy-nine constituents, accounting for 88.8-98.1% total composition extracts, identified. The common feature was high content terpenoids fatty acidderived compounds, while prevalence acid-derived compounds. A disk diffusion method used evaluation...

The essential oils from dried aerial parts of Satureja kitaibelii Wierzb. ex Heuff., collected at three various sites in Serbia, were analyzed by gas chromatography and chromatography/mass spectrometry. One hundred sixty-three components identified all investigated samples, 132 the oil site Devojački grob, 124 coming Sićevačka klisura site, 146 Visočka Ržana, accounting 97.3, 93.9, 95.6% total oils, respectively. most abundant component was geraniol amounting 24.0 to 30.3%, making up about...

Although ethnopharmacologically renowned, wax constituents of Dianthus species were sporadically studied. A combination GC-MS analysis, synthesis, and chemical transformations enabled the identification 275 diethyl-ether washings aerial parts and/or flowers six taxa (Dianthus carthusianorum, D. deltoides, giganteus subsp. banaticus, integer minutiflorus, petraeus, superbus) one Petrorhagia taxon (P. prolifera) from Serbia. Seventeen these (nonacosyl benzoate, additional 12 benzoates with...

Considering the facts that phenolic compounds have many pharmacological effects, as well antioxidant effect of has been proven in various experimental systems, aim this research was to determine content total phenols and flavonoids evaluation activity ethanol, ethyl acetate chloroform extracts fruits leaves plant species Crataegus monogya Jacq., which is known common hawthorn. The determined by spectrophotometric method using Folin-Ciocalteu reagent aluminum chloride. In vitro tested...

Abstract Some carnation species ( Dianthus spp., Caryophyllaceae) exhibit a strong resistance to drought stress that is connected with the increased surface wax formation. Wax composition unknown for majority of spp. Herein, mass spectral and gas chromatographic data, in combination synthesis chemical transformations (transesterification dimethyl disulfide adducts), enabled identification 151 constituents diethyl‐ether washings fresh flowers cruentus Griseb . from Serbia. The flower...

The content and composition of fatty acids alkanes Satureja adamovicii Silic fukarekii were analized by GC. It was found that unsaturated prevailed the major components palmitic, oleic, linoleic linolenic acids. hydrocarbon fractions pentane extracts shown to consist alkane homologues (C17 C34) with nonacosane hentriacontane being prevailing compounds.

Abstract Introduction Minor plant constituents are difficult to identify due the challenging isolation and acquiring of reliable spectral data. Essential oils abound in such minor that might be high importance for their (e.g. olfactory) properties. The presence new is usually inferred from gas chromatography mass spectrometry (GC‐MS) analyses provide only a spectrum retention data, which insufficient allow positive identification. Objective To unknown constituent essential oil Achillea...

For the first time, chemical composition of P. longifolium essential oils (EO) and head space (HS) volatiles obtained from fresh leaves, harvested in different phases plant development, inflorescences was compared. The major contributor leaves oil vegetative phase (LD) β-elemene (44.1%). On cotrary, (22.5%) second most abundant component, while ( E )-β-ocimene (26.7%) cis -lanalool oxide (furanoid, 21.9%) third represented compound collected blossoming (LF). )-β-Ocimene both HS leaf samples...

Synthesis, spectral characterization, and evaluation of in vitro antioxidant activity a new coumarin derivative, 4- ((1,3,4-thiadiazol-2-yl)amino)-3-nitro-2H-chromene-2-one, are described. The synthesis the product was performed three reaction steps, with good overall yield (78%). structure corroborated by detailed analysis, including 1D 2D NMR experiments (1H- 13C NMR; 1H-1H COSY, NOESY, HSQC, HMBC). evaluated using DPPH test. synthesized compound possesses free-radical scavenging activity,...

Abstract C 22 H 18 O 10 Zn, triclinic, P 1̄ (no. 2), a = 7.9616(3) Å, b 9.5386(3) c 14.2569(4) α 81.713(3)°, β 82.724(3)°, γ 73.103(3)°, V 1021.03(6) Å 3 , Z 2, R gt ( F ) 0.0223, wR ref 2 0.0603, T 295(2) K.

Abstract C 16 H 12 N 2 O 4 , triclinic, P 1̄ (no. 2), a = 10.7105(5) Å, b 11.2685(5) c 13.0145(6) α 99.292(4)°, β 109.607(4)°, γ 96.771(4)°, V 1435.01(12) Å 3 Z 4, R gt (F) 0.0427, wR ref (F ) 0.1124, T 295(2) K.

This research involves the reaction of 4-chloro-3-nitrocoumarin and (4-methoxyphenyl)methanamine, whereby a novel coumarin derivative 4-[(4-methoxybenzyl) amino]-3-nitro-2H-chromen-2-one was obtained in good yield. The carried out ethyl acetate, presence triethylamine. Also, detailed spectral analysis new is presented. Resonance assignment achieved using one( 1H NMR 13C NMR) two-dimensional techniques (1H1H-COSY, NOESY, HSQC, HMBC). NOESY correlations protons from arylamino substituent core...