Xanthine oxidase (XO) is an important enzyme catalyzing the hydroxylation of hypoxanthine to xanthine and uric acid which excreted by kidneys. Excessive production and/or inadequate excretion results in hyperuricemia. This paper presents a detailed review methods isolation, determination activity, effect plant extracts their constituents on it. Determining content activities XO can be used for diagnostic purposes. Testing inhibition detection potentially effective compounds or that treat...

Purpose: To assess some terpenes from herbal products for possible inhibitory effects on serum α- amylase in order to ascertain their potential usefulness the prevention and/or treatment of diabetes Type 2.Methods: Solutions (citral, eukalyptol, β-pinene, myrcene, eugenol and terpineol) deonized water were prepared by ultrasonic manual mixing four different concentrations ranging 0.39 – 5.50 µmol cm-3. Commercial sera (with normal-N high-H enzyme activity) used as a source α-amylase....

The chemical composition of the essential oil Micromeria cristata and juliana was determined by GC-MS analysis. Among 36 identified compounds M. oil, isoborneol (11.3%), borneol (8.5%), verbenone (8.2%), 10-epi-α-cadinol thujan-3-ol, were found to be major components. main constituents verbenol (11.8%), thymol (10.8%), caryophyllene oxide (10.5%), (9.3%) myrtenal (7.1%). in-vitro antimicrobial activity ethanolic solution oils investigated disk diffusion method with ampicillin as standard...

The essential oils from dried aerial parts of Satureja kitaibelii Wierzb. ex Heuff., collected at three various sites in Serbia, were analyzed by gas chromatography and chromatography/mass spectrometry. One hundred sixty-three components identified all investigated samples, 132 the oil site Devojački grob, 124 coming Sićevačka klisura site, 146 Visočka Ržana, accounting 97.3, 93.9, 95.6% total oils, respectively. most abundant component was geraniol amounting 24.0 to 30.3%, making up about...

Chemical composition of the headspace volatiles and essential oils isolated from different parts Ferulago sylvatica was determined by GC GC/MS analyses. The results showed that obtained aerial roots were similar regarding number identified compounds main components. However, plant organs significant differences in chemical composition. Myrcene most abundant component inflorescences shoots volatiles, while α-pinene make up over 50% root volatiles. Only three components oil with...

Abstract The chemical composition of the essential oil aerial parts Ajuga chamaepitys (L.) Schreber ssp. chia (Schreber) Arcangeli collected on Vidlic Mountain (Serbia) from two neighboring localities: normal environmental conditions (NEC) and post fire (PFEC) has been studied by GC GC/MS. Thirty eight compounds were identified in NEC thirty four PFEC accounted 98.3 % 98.2 total oil, respectively. major constituents were: α-pinene (10.9%, 5.4%), β-pinene (22.0%, 14.8%), germacrene D (16.2%,...

Three lichen secondary metabolites atranorin (1), evernic acid (2), and usnic (3), were evaluated for their in vitro clastogenic antiproliferative effects on human lymphocytes using the cytochalasin-B blocked micronucleus (CBMN) assay at concentrations of 2 microg/mL, 4 microg/mL 6 final culture solution. The frequency (MN) was scored binucleated cells, cytokinesis-block proliferation index (CBPI) calculated. Among tested compounds, 3 exhibited most prominent effect decreasing MN range 42.5%...

Volatiles of diethyl ether extract (DE), ethyl acetate (EE), and hexane (HE) Artemisia scoparia Waldst. et Kit. were analyzed by gas chromatography with flame ionization detector chromatography-mass spectrometry. In both DE EE, the main compound was scoparone (24.0% 86.1%, respectively) while in HE, alkanes dominant nonacosane as most represented (19.4%). Antimicrobial activity tested against 4 bacterial strains 1 fungal strain using disc-diffusion method. Tested samples inactive...

Disadvantage of some organic pesticides is their low water solubility. Among other substances, cyclodextrins and modified were considered as agents for improving The solubility poorly soluble pesticides, dimethoate, simazine, linuron thiram, was determined in aqueous solution methylated-?-cyclodextrin (mbCD) by ultraviolet spectrophotometry. Methylated-?-cyclodextrin obtained the Hawort method characterized 1H NMR HPLC data. average degree substitution 13.8. Methylation done either on C-2,...

Chemical composition and antibacterial activity of the essential oils isolated from fruits leaves Peucedanum austriacum (Jacq.) W.D.J. Koch were determined in order to define their medical potential. An analysis leaf fruit by gas chromatography (GC) GC/mass spectrometry (GC/MS) resulted identification 141 different components, representing 93.6% 96.1% total oils. The most abundant class compounds oil was monoterpenoids (64.0%) sesquiterpenoids (82.0%). major contributors β-phellandrene...

Abstract The composition of the essential oil aerial parts Micromeria kosaninii Šilic, parviflora (Vis.) Re-incheb. and juliana (L.) Benth. ex Reich was analyzed by GC GC/MS. One hundred twenty-four compounds were identiified in M. kossaninii oil, 143 111 accounting for more than 96.0%, 97.5% 97.9% total oils, respectively. Sixty-three common all three oils. major constituents both oils borneol (8.2% 9.3%, respectively), isomeric verbenols (11.7% 8.7%) furanoid linalool oxides (9.8% 6.5%)....

We report the total phenolic (TPC; expressed as gallic acid equivalents, GAE, per milligram of dry extract weight) and flavonoid contents (TFC; quercetin QE, antimicrobial antioxidant activities essential oil hexane, diethyl ether, ethyl acetate methanol extracts Mentha pulegium L. (Lamiaceae) collected in Serbia. The content was range 129.43-388.29 ?g GAE/mg, while TFC ranged from 57.81 to 160.94 QE/mg; highest TPC were found extract. activity (against five bacteria two fungi species)...

Abstract The composition of the essential oil Balkan peninsula endemic plant Micromeria albanica (Griseb. ex. K. Maly) Silic was analyzed for first time by GC and GC/MS. oil, which present in 0.9% (v/w) yield, found to contain piperitenone oxide (44.0%) as major constituent.

Since ancient times, medicinal plants and pharmacologically active products obtained from different natural sources play an important role in human health. Plants belonging to the genus Artemisia possess a great biological potential it is well-studied fields such as systematics (including molecular phylogenetics) genome organization. Many species of (e.g., A. absinthium, annua, vulgaris, abrotanum, arborescens) are widely exploited, because their high economic value medicines, food...

Since the ancient times, people have used essential oils as a cure because they noticed their beneficial effects on human mind and body. What did not know was how these actually affected body, well exactly what component or more of them were responsible for activity particular oil. Therefore, lot attention has recently been paid to detailed identification constituents oil determination biological itself, those identified constituents. The aim this paper is systematize most used, accessible...

This research was based on the examination of total phenolic content, antioxidant and antimicrobial activities hexane, diethyl ether, ethyl acetate, methanol extracts Origanum heracleoticum L. grown in Serbia. The activity determined against five bacteria two fungi using disk diffusion method. content O. solvent different tests were used for screening capacity. highest found acetate extract (848.48 μg GAE/mg dry extract) (733.43 extract). showed that had strongest activity. correlation...