A5038813690- Research on Leishmaniasis Studies
- Drug Solubulity and Delivery Systems
- Antifungal resistance and susceptibility
- 3D Printing in Biomedical Research
- Advanced Drug Delivery Systems
- Crystallization and Solubility Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Trypanosoma species research and implications
- Advancements in Transdermal Drug Delivery
- Inhalation and Respiratory Drug Delivery
- Crystallography and molecular interactions
- Pharmaceutical studies and practices
- Nail Diseases and Treatments
- Analytical Methods in Pharmaceuticals
- Toxin Mechanisms and Immunotoxins
- Parasites and Host Interactions
- Antibiotics Pharmacokinetics and Efficacy
- Synthesis and Biological Evaluation
- Higher Education Teaching and Evaluation
- Microencapsulation and Drying Processes
- RNA Interference and Gene Delivery
- Fungal Infections and Studies
- Nanoparticle-Based Drug Delivery
- Pesticide Exposure and Toxicity
Universidad Complutense de Madrid
2016-2025
Universidade Estadual Paulista (Unesp)
2020
Trinity College Dublin
2015-2019
University College London
2016-2018
Universidad Cardenal Herrera CEU
2018
Bellingham Technical College
2015
Abstract Blended learning has risen in popularity the last two decades as it been shown to be an effective approach for accommodating increasingly diverse student population higher education and enriching environment by incorporating online teaching resources. Blending significant elements of such face‐to‐face, self‐paced leads better experiences outcomes more efficient course management practices if combined appropriately. Hence, appropriate systematic dynamic blended design is crucial a...
There are very few drug delivery systems that target key organs via the oral route, as advances normally address gastrointestinal dissolution, permeation, and stability. Here we introduce a nanomedicine in which nanoparticles, while also protecting from gastric degradation, taken up by epithelia transported to lung, liver, spleen, thus selectively enhancing bioavailability these diminishing kidney exposure (relevant nephrotoxic drugs). Our work demonstrates, for first time, particle uptake...
Metabolic syndrome is a collection of abnormalities, including at least three the following insulin resistance, hypertension, dyslipidemia, type 2 diabetes, obesity, inflammation, and non-alcoholic fatty liver disease. 3D printed solid dosage forms have emerged as promising tool enabling fabrication personalized medicines offering solutions that cannot be achieved by industrial mass production. Most attempts found in literature to manufacture polypills for this contain just two drugs....
The incidence of fungal pulmonary infections is known to be on the increase, and yet there an alarming gap in terms marketed antifungal therapies that are available for administration. Amphotericin B (AmB) a highly efficient broad-spectrum only as intravenous formulation. Based lack effective antiparasitic treatments, aim this study was develop carbohydrate-based AmB dry powder inhaler (DPI) formulation, prepared by spray drying. Amorphous microparticles were developed combining 39.7 % with...
Although not readily accessible yet to many community and hospital pharmacists, fuse deposition modelling (FDM) is a 3D printing technique that can be used create pharmaceutical dosage form by employing drug loaded filaments extruded via nozzle, melted deposited layer layer. FDM requires printable filaments, which are commonly manufactured hot melt extrusion, identifying suitable extrudable drug-excipient mixture sometimes challenging. We propose here the use of passive diffusion as an...
The combination of lopinavir/ritonavir remains one the first-line therapies for initial antiretroviral regimen in pediatric HIV-infected children. However, implementation this recommendation has faced many challenges due to cold-chain requirements, high alcohol content, and unpalatability ritonavir-boosted lopinavir syrup. In addition, administration crushed tablets shown a detriment oral bioavailability both drugs. Therefore, there is clinical need develop safer better formulations adapted...
Vesicants are chemical warfare agents (CWAs) capable of causing severe skin damage and systemic toxicity. Melatonin, known for its anti-inflammatory antioxidant properties, can mitigate the effects these agents. Self-nano-emulsifying drug delivery systems (SNEDDS) containing a high melatonin concentration (5 %, 50 mg/g) were optimized using quality-by-design approach from biocompatible, non-irritant excipients with particle size about 100 nm. The melatonin-loaded SNEDDS showed 43-fold...