A5076642853- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Drug Solubulity and Delivery Systems
- Surfactants and Colloidal Systems
- Nanoparticle-Based Drug Delivery
- Inhalation and Respiratory Drug Delivery
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- biodegradable polymer synthesis and properties
- Lipid Membrane Structure and Behavior
- Nanocomposite Films for Food Packaging
- RNA Interference and Gene Delivery
- Polysaccharides Composition and Applications
- Advanced Polymer Synthesis and Characterization
- Microencapsulation and Drying Processes
- Polymer Surface Interaction Studies
- Proteins in Food Systems
- Cystic Fibrosis Research Advances
- Enzyme Catalysis and Immobilization
- Microfluidic and Bio-sensing Technologies
- Nanoplatforms for cancer theranostics
- Essential Oils and Antimicrobial Activity
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Environmental Chemistry and Analysis
University of Urbino
2016-2025
University of Nottingham
2010
Critical Pharmaceuticals (United Kingdom)
2010
Atherosclerosis still represents a major driver of cardiovascular diseases worldwide. Together with accumulation lipids in the plaque, inflammation is recognized as one key players formation and development atherosclerotic plaque. Systemic anti-inflammatory treatments are successful reducing disease burden, but correlated severe side effects, underlining need for targeted formulations. In this work, curcumin chosen payload model further loaded lignin-based nanoparticles (NPs). The NPs then...
Current strategies to treat pelvic organ prolapse (POP) or stress urinary incontinence (SUI), include the surgical implantation of vaginal meshes. Recently, there have been multiple reports issues generated by these meshes conventionally made poly(propylene). This material is not ideal candidate, due its mechanical properties leading complications such as chronic pain and infection. In present manuscript, we propose use an alternative material, thermoplastic polyurethane (TPU), loaded with...
The aim of the present work is to investigate if conditions can be devised where PEGylation chitosan would reduce its toxicity toward nasal mucosa while maintaining ability open cellular tight junctions and, consequently, produce an enhancement macromolecular permeability. A series mPEG-g-chitosan copolymers with varying levels mPEG substitution, molecular weight, and weight were synthesized by grafting carboxylic acid-terminated mPEGs (Mw 1.9 5.0 × 103 g mol−1) chitosans 28.9 82.0 using a...
In this study, di- and triblock copolymers based on polyethylene glycol polylactide were synthesized by ring-opening polymerization characterized proton nuclear magnetic resonance gel permeation chromatography. Nanoparticles containing noscapine prepared from these biodegradable biocompatible using the nanoprecipitation method. The nanoparticles for size drug entrapment efficiency, their morphology checked transmission electron microscopy imaging. Artificial neural networks constructed...
Abstract The last decade has seen remarkable advances in the development of drug delivery systems as alternative to parenteral injection‐based insulin. Neonatal Fc receptor (FcRn)‐mediated transcytosis been recently proposed a strategy increase transport drugs across intestinal epithelium. FcRn‐targeted nanoparticles (NPs) could hijack FcRn transcytotic pathway and cross epithelial cell layer. In this study, novel nanoparticulate system for insulin based on porous silicon NPs is proposed....
The antimicrobial activity of several essential oils (EOs) and their related microemulsions (MEs) was investigated. EOs were obtained from Cannabis sativa L. cv CS (C. sativa), Carum carvi carvi), Crithmum maritimum maritimum), Cuminum cyminum cyminum), x Cupressocyparis leylandii A.B. Jacks & Dallim. leylandii), Cupressus arizonica Greene arizonica), Ferula assa-foetida (F. assa-foetida)., gummosa Boiss. gummosa), Juniperus communis (J. communis), pfitzeriana (Spath) P.A. Schmidt...
In recent years, 3D printing has attracted great interest in the pharmaceutical field as a promising tool for on-demand manufacturing of patient-centered forms. Among existing techniques, direct powder extrusion (DPE) resulted most practical approach thanks to possibility directly process excipients and drugs single step. The main goal this work was determine whether different grades ethylene vinyl acetate (EVA) copolymer might be employed new feedstock materials DPE technique manufacture...
Diabetic foot ulcers (DFUs) are a crucial complication of diabetes, as in diabetic wound, each step the physiological healing process is affected. This entails more easily infectable and delayed tissue regeneration due to inflammation that occurs, leading drastic decrease overall patient's quality life. As strategy manage DFUs, skin alternatives wound dressings currently receiving lot attention they keep environment "under control", while providing bioactive compounds help infection promote...