About
Contact & Profiles
A5062919666
Research Areas
- Cancer Treatment and Pharmacology
- Cancer, Lipids, and Metabolism
- Ubiquitin and proteasome pathways
- Angiogenesis and VEGF in Cancer
- Pain Management and Treatment
- RNA modifications and cancer
Danish Cancer Society
2023
Abstract Cancer cells are dependent on cholesterol, and they possess strictly controlled cholesterol homeostasis mechanisms. These allow them to smoothly switch between synthesis uptake fulfill their needs adapt environmental changes. Here we describe a mechanism of how cancer employ oncogenic growth factor signaling promote utilization extracellular via Myeloid Zinc Finger 1 (MZF1)-mediated Niemann Pick C1 (NPC1) expression upregulated macropinocytosis. Expression p95ErbB2, highly...
10.1038/s41388-023-02771-x
article
EN
cc-by
Oncogene
2023-07-07
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