A5089517130- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- Treatment of Major Depression
- Microbial Metabolism and Applications
- Phytochemical Studies and Bioactivities
- Schizophrenia research and treatment
- Olfactory and Sensory Function Studies
- Morinda citrifolia extract uses
- Pharmacological Effects of Natural Compounds
- Biochemical Analysis and Sensing Techniques
Delta State University
2023-2024
University of Ibadan
2016-2020
Diosmin (DSM), commonly isolated from various plants, is a citrus nutrient that has been shown to increase intracellular antioxidant capacity and assuage symptoms associated with neurological disorders. Deficiency in the system implicated pathogenesis of schizophrenia. The use antioxidants as neuroprotectants suppress schizophrenia pathology increasingly being sought. Hence, this study investigated effects DSM on schizophrenia-like behavior underlying changes biomarkers oxidative stress...
Abstract Objectives Diosmin (DSM), commonly isolated from various plants, is a citrus nutrient that has been shown to increase intracellular antioxidant capacity and assuage symptoms associated with neurological disorders. Deficiency in the system implicated pathogenesis of schizophrenia. The use antioxidants as neuroprotectants suppress schizophrenia pathology increasingly being sought. Hence, this study investigated effects DSM on schizophrenia-like behavior underlying changes biomarkers...
Current evidences support the inhibition of oxidative and inflammatory signaling mechanisms in treatment schizophrenia; as cure for this disease still remains limited. Doxycycline is a tetracycline antibiotic (a minocycline congener) with strong antioxidant anti-inflammatory properties, better pharmacokinetic profiles. Preclinical evidence indicates that possesses antipsychotic properties. This present study was designed to evaluate effect doxycycline on schizophrenia-like behaviors, well...