- Hedgehog Signaling Pathway Studies
- Developmental Biology and Gene Regulation
- Global Health Workforce Issues
- Global Maternal and Child Health
- Maternal and Perinatal Health Interventions
- Epigenetics and DNA Methylation
- Neurogenesis and neuroplasticity mechanisms
- Congenital heart defects research
- Fetal and Pediatric Neurological Disorders
- Research in Social Sciences
- Pluripotent Stem Cells Research
- Cellular transport and secretion
- Child and Adolescent Health
- Genetics and Neurodevelopmental Disorders
- Cell Adhesion Molecules Research
- Axon Guidance and Neuronal Signaling
- RNA Research and Splicing
- Patient Satisfaction in Healthcare
- Cellular Mechanics and Interactions
- Renal and related cancers
- Healthcare Systems and Technology
- Electronic Health Records Systems
- Fibroblast Growth Factor Research
- RNA regulation and disease
- Nuclear Receptors and Signaling
World Health Organization
2012
Consejo Superior de Investigaciones Científicas
2003-2009
Mount Sinai Hospital
2007
Lunenfeld-Tanenbaum Research Institute
2007
University of Toronto
2007
Toronto General Hospital
2007
Universitat de Miguel Hernández d'Elx
2003-2006
The Wiskott-Aldrich syndrome protein (WASp) plays a major role in coupling T cell antigen receptor (TCR) stimulation to induction of actin cytoskeletal changes required for activation. Here, we report that WASp inducibly binds the sorting nexin 9 (SNX9) cells and WASp, SNX9, p85, CD28 colocalize within clathrin-containing endocytic vesicles after TCR/CD28 costimulation. implicated clathrin-mediated endocytosis, via its SH3 domain uses PX interact with phosphoinositol 3-kinase regulatory...