- Computational Drug Discovery Methods
- Image Enhancement Techniques
- Advanced Vision and Imaging
- Advanced Image Processing Techniques
- Click Chemistry and Applications
- Synthesis and bioactivity of alkaloids
- Phytochemistry and Bioactivity Studies
- SARS-CoV-2 and COVID-19 Research
- Protein Degradation and Inhibitors
- Advanced Computational Techniques and Applications
- Advanced Image and Video Retrieval Techniques
- Robotics and Automated Systems
- COVID-19 epidemiological studies
- Robotics and Sensor-Based Localization
- Biological Stains and Phytochemicals
- Antimicrobial Peptides and Activities
- Chromatography in Natural Products
- Infection Control and Ventilation
- Service-Oriented Architecture and Web Services
- Business Process Modeling and Analysis
- Image and Video Quality Assessment
- Pharmacological Effects of Natural Compounds
- Video Surveillance and Tracking Methods
- Synthesis and biological activity
- Robotic Path Planning Algorithms
Shanghai University of Traditional Chinese Medicine
2021-2025
Tianjin University
2015-2023
Nanjing University of Information Science and Technology
2011
Commercial airliners have played an important role in spreading the SARS-CoV-2 virus worldwide. This study used computational fluid dynamics (CFD) to simulate transmission of on a flight from London Hanoi and another Singapore Hangzhou. The dispersion droplets different sizes generated by coughing, talking, breathing activities cabin infected person was simulated means Lagrangian method. contained expiratory traveled with air distribution inhaled other passengers. Infection determined...
The present work investigates virucidal and antiviral compounds in the extracts of seed embryos a lotus, Nelumbo nucifera, Thai ginseng, Kaempferia parviflora. Separation led to identification against SARS-CoV-2. Neferine (1) nuciferine (3) from N. as well their respective HCl salts (2 4), exhibited activities Virucidal activity neferine salt (2) (EC50 4.78 µM) was 7.5 times better than its free-base, 36.01 µM), also improved selectivity index (SI), showing less cytotoxicity 1. This...
The 3C-like protease (3CL pro ) is a crucial target in anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) drug design. Herein, we performed high-throughput synthesis of catechol derivatives from the bioactive catechol-terminal alkyne scaffold A4 , by using modular click chemistry. Subsequently, conducted two rounds SARS-CoV-2 3CL inhibition screening and selected seven compounds for further efficacy validation. Compound P1-E11 had potent inhibitory effects toward (IC 50 = 2.54...
MAV (Micro Air Vehicle) can be used for many applications such as the investigation of inhospitable environments, regions contaminated by nuclear pollution or hazardous material and other inaccessible areas. For kind purposes, a small machine that autonomously fly seems to appropriate. Our research group selects Quad-Rotor our platform, achieved automated take-off, landing, hovering, way-point navigation, vision-based navigation flight. However, payload current platform is low (about...