Wen Wei

ORCID: 0000-0002-0516-8430
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About
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Research Areas
  • Ginkgo biloba and Cashew Applications
  • Lipid metabolism and biosynthesis
  • Vitamin C and Antioxidants Research
  • Immune Response and Inflammation
  • interferon and immune responses
  • Traditional Chinese Medicine Analysis
  • Adipose Tissue and Metabolism
  • RNA Research and Splicing
  • Retinoids in leukemia and cellular processes
  • Gut microbiota and health
  • Biochemical Analysis and Sensing Techniques
  • Adenosine and Purinergic Signaling
  • Aquaculture disease management and microbiota
  • Stress Responses and Cortisol
  • RNA and protein synthesis mechanisms
  • Aquaculture Nutrition and Growth
  • Animal Nutrition and Physiology
  • Neurological Disease Mechanisms and Treatments
  • Mitochondrial Function and Pathology

Nanjing Drum Tower Hospital
2022-2023

Model Animal Research Center
2019-2023

Southwest University of Science and Technology
2021

Hubei Academy of Agricultural Sciences
2021

Animal Science Research Institute
2021

State Key Laboratory of Pharmaceutical Biotechnology
2019

Nanjing University
2019

Superoxide dismutase (SOD) is an attractive therapeutic agent to ameliorate oxidative stress that critical for the initiation and progression of inflammatory bowel disease (IBD). However, short life SOD limits its clinical application. In this study, we aim examine effects a hyperthermostable from Thermus thermophilus HB27 (TtSOD) treatment experimentally induced IBD.A recombinant TtSOD was expressed purified Escherichia coli, were examined in 2 experimental IBD animal models.In by...

10.1093/ibd/izz097 article EN Inflammatory Bowel Diseases 2019-05-08

Insulin is a potent inducer of mRNA transcription and translation, contributing to metabolic regulation. has also been suggested regulate stability through the processing body (P-body) molecular machinery. However, whether how insulin regulates via P-bodies not clear. Here we show that E3-ligase TRIM24 critical factor linking signalling P-bodies. Upon stimulation, protein kinase B (PKB, known as Akt) phosphorylates stimulates its shuttling from nucleus into cytoplasm. interacts with several...

10.1038/s41467-022-31735-0 article EN cc-by Nature Communications 2022-07-08

Cage rearing has critical implications for the laying duck industry because it is convenient feeding and management. However, caging stress a type of chronic that induces maladaptation. Environmental responses have been extensively studied, but no detailed information available about comprehensive changes in plasma metabolites at different stages ducks. We designed this experiment to analyze effects on performance parameters oxidative indexes ducks.Liquid chromatography tandem mass...

10.5713/ab.21.0241 article EN cc-by Animal Bioscience 2021-08-24

Abstract Background: Vitamin A (VA) is an essential fat-soluble vitamin that contributes to the normal metabolism of intestinal epithelial cells (IEC), fights infections and enhances immunity. Retinoic acid (RA) physiological metabolite VA, which increased under oxidative stress has important function. We studied protective mechanism VA/RA in H 2 O -induced primary duck IECs. Cells were distributed into 5 groups: blank control group (CG1), positive (CG2), high concentration retinoic (TG1)...

10.21203/rs.3.rs-871297/v1 preprint EN cc-by Research Square (Research Square) 2021-09-13
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