- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Innovations in Medical Education
- Adrenal and Paraganglionic Tumors
- Parathyroid Disorders and Treatments
- Hormonal Regulation and Hypertension
- Head and Neck Anomalies
- Diversity and Career in Medicine
- Patient-Provider Communication in Healthcare
- Pancreatic and Hepatic Oncology Research
- BRCA gene mutations in cancer
- Surgical Simulation and Training
- Pituitary Gland Disorders and Treatments
- Genetic Syndromes and Imprinting
- Thyroid Disorders and Treatments
- Enhanced Recovery After Surgery
- Voice and Speech Disorders
- Telemedicine and Telehealth Implementation
- Evaluation of Teaching Practices
- Radiation Dose and Imaging
- Cancer, Hypoxia, and Metabolism
- Simulation-Based Education in Healthcare
- Neuroendocrine Tumor Research Advances
- History of Medical Practice
- Surgical Sutures and Adhesives
University of Nebraska Medical Center
2018-2025
University of Nebraska at Omaha
2019-2024
Beth Israel Deaconess Medical Center
2020
Nebraska Medical Center
2020
Columbia University Irving Medical Center
2010-2019
Keck Hospital of USC
2019
University of Nebraska–Lincoln
2019
Massachusetts General Hospital
2016-2018
Harvard University
2016
Columbia University
2012-2016
BACKGROUND: Cross-sectional imaging increases accuracy in diagnosing appendicitis. We hypothesized that a radiation-free pathway of ultrasonography selectively followed by MRI would not change clinical end points compared with computed tomography (CT) for diagnosis acute appendicitis children. METHODS: retrospectively reviewed children (<18 years old) who had diagnostic suspected between November 2008 and October 2012. Before 2010 CT was used as the primary modality (group A);...
Parathyroid carcinoma is a rare malignancy, representing 0.005% of all cancers and 0.5%-1% parathyroid disorders. occurs equally in males females, as opposed to primary hyperparathyroidism, which has female predominance. Patients with present symptoms hypercalcemia, similar those benign hyperparathyroidism. should be suspected when calcium or hormone levels are high. Because the difficulty discerning from adenoma preoperatively, diagnosis often made only after parathyroidectomy. The goals...
Dosimetry helps calculate the optimal iodine-131 (I-131) dose for treating metastatic differentiated thyroid cancer (DTC). We aimed to evaluate if recombinant human TSH (rhTSH) and hormone withdrawal (THW) are equivalent methods of preparation dosimetry-guided I-131 therapy in DTC. performed a retrospective cohort study 51 adults with DTC who received dosimetry from 2010 through 2022. Gamma camera blood activity measurements were taken following pretherapeutic dose. Statistical analysis...
Background: Thyroid cancer incidence is increasing. The effect of diagnosis and treatment on health-related quality life (HRQoL) an essential variable in the absence a change span for majority patients. HRQoL instruments, with data useful between-disease comparisons, are being increasingly used health policy outcomes evaluation. Variation exits among instruments based impact specific disease. We assessed which four well-validated, preference-based surveys detect changes clinical intervention...
Objective: To assess relative clinical and economic performance of the revised American Thyroid Association (ATA) thyroid cancer guidelines compared to current standard care. Background: Diagnosis in United States has tripled whereas mortality only marginally increased. Most patients present with small papillary carcinomas have historically received at least a total thyroidectomy as treatment. In 2015, ATA released recommending an option for active surveillance (AS) carcinoma lobectomy...
Objective: To evaluate the relative importance of treatment outcomes to patients with low-risk thyroid cancer (TC). Summary Background Data: Overuse total thyroidectomy (TT) for TC is common. Emotions from a diagnosis may lead choose TT resulting in that do not align their preferences. Methods: Adults clinically enrolled prospective, multi-institutional, longitudinal cohort study 11/2019-6/2021. Participants rated at time surgical decision and again 9 months later by allocating 100 points...
Analysis of cytologically indeterminate thyroid nodules with Afirma Gene Expression Classifier (GEC) and Genomic Sequencing (GSC) can reduce surgical rate increase malignancy surgically resected nodules.Retrospective cohort analysis all adults from January 2013 through December 2019. We compared rates those without molecular testing to GEC or GSC, analyzed test performance between identified variables associated testing.468 were included. No was performed in 273, 71 had GEC, 124 GSC testing....
BRAFV600E is the most common mutation in papillary thyroid carcinoma (PTC) and can be associated with aggressive disease. Previously, a highly sensitive blood RNA-based assay was reported. The objective of this study to assess correlation circulating tumor RNA levels surgical medical treatment.Circulating were assessed (i) murine model undifferentiated (anaplastic) known undergoing BRAFV600E-inhibitor (BRAFi) treatment, (ii) 111 patients enrolled prior thyroidectomy (n = 86) or treatment...