Leonie Grellier

ORCID: 0000-0002-0529-3530
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About
Contact & Profiles
Research Areas
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Liver Disease Diagnosis and Treatment
  • Inflammatory Bowel Disease
  • Systemic Lupus Erythematosus Research
  • Colorectal Cancer Treatments and Studies
  • Iron Metabolism and Disorders
  • HIV/AIDS drug development and treatment
  • Alcohol Consumption and Health Effects
  • Monoclonal and Polyclonal Antibodies Research
  • Genetic factors in colorectal cancer
  • Cutaneous Melanoma Detection and Management
  • Liver Diseases and Immunity
  • Trace Elements in Health
  • Hemoglobinopathies and Related Disorders
  • Chemotherapy-related skin toxicity

Isle of Wight NHS Trust
2021

Hôpital Nord
2014

Southlands Hospital
2007

The Royal Free Hospital
1996-2000

University College London
1996-2000

This open, multicenter study was conducted to evaluate the efficacy and safety of lamivudine prophylaxis given chronic hepatitis B virus-(HBV) infected patients before after orthotopic liver transplantation (OLT). We now present long-term data that follow our previous short-term report.Twenty-three were treated with (100 mg orally, daily); 13 (57%), serum HBV DNA positive (Abbott Genostics, Abbott Laboratories, Chicago, IL) at entry. Patients received for least 4 weeks OLT, up 50 months...

10.1097/00007890-200009150-00018 article EN Transplantation 2000-09-01

Summary. The presence or absence of antibodies to the second envelope protein (anti‐E2) hepatitis C virus (HCV) was determined in stored sera taken from a cohort 87 Irish women with HCV (anti‐HCV) who were all infected by genotype 1b contaminated anti‐D immunoglobulin given 1977. Anti‐E2 found 16 patients (100%) RNA positive but only 31 50 (62%) antibody recombinant immunoblot assay (RIBA) negative. In remaining 21 had indeterminate assays and repeatedly negative on testing for RNA, anti‐E2...

10.1046/j.1365-2893.1997.00074.x article EN Journal of Viral Hepatitis 1997-11-01

Background Chronic ulcerative colitis is a large bowel inflammatory condition associated with increased colorectal cancer risk over time, resulting in 1000 colectomies per year the UK. Despite intensive colonoscopic surveillance, 50% of cases progress to invasive before detection. Detecting early (precancer) molecular changes by analysing biopsies from routine colonoscopy should increase neoplasia Objectives To establish deoxyribonucleic acid (DNA) marker panel neoplastic patients. develop...

10.3310/eme08010 article EN publisher-specific-oa Efficacy and Mechanism Evaluation 2021-01-01
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