A5038410186- RNA Interference and Gene Delivery
- Inhalation and Respiratory Drug Delivery
- MicroRNA in disease regulation
- Antimicrobial Peptides and Activities
- Macrophage Migration Inhibitory Factor
- Nanoparticle-Based Drug Delivery
- Dermatology and Skin Diseases
- Bee Products Chemical Analysis
- Tannin, Tannase and Anticancer Activities
- Immune cells in cancer
- Seaweed-derived Bioactive Compounds
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Enzyme Catalysis and Immobilization
- RNA Research and Splicing
Universidade Federal de Juiz de Fora
2020-2024
Macauba oil-loaded polymeric micelles exhibit antimigratory, antiproliferative, and cytotoxic activities in triple-negative breast cancer cells, suggesting potential as a therapeutic agent for this aggressive type.
Breast cancer is the most common type of that affects and kills women annually in world. It impacts more than two million responsible for death approximately 25% them. Almost 70% breast diagnoses are positive hormone receptor have a good prognosis. However, resistance to drugs used therapy, such as tamoxifen, usual about 40% recurrences do not respond it. In some cases, overexpression HOXB7 gene related this mechanism its silencing can reverse response tamoxifen. Here, we copolymer-coated...
Este estudo propõe preparar sistemas nanocarreadores para solubilização e incorporação de ativos hidrofóbicos realizar sua caracterização físico-química. Um sistema nanoparticulado composto por lipídios origem natural copolímeros em bloco foi designado a dois hidrofóbicos, constituindo duas formulações nanoestruturadas diferentes. Após determinação do ponto fusão perfil cromatográfico da manteiga empregada, as foram preparadas fusão-emulsificação, sendo aquecidas homogeneizadas aparelhos...