A5090770573- Temporomandibular Joint Disorders
- Transcranial Magnetic Stimulation Studies
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Facial Nerve Paralysis Treatment and Research
- Dysphagia Assessment and Management
- Dental Implant Techniques and Outcomes
- Stroke Rehabilitation and Recovery
- Muscle Physiology and Disorders
- Trigeminal Neuralgia and Treatments
- Periodontal Regeneration and Treatments
- Oral Health Pathology and Treatment
- dental development and anomalies
- Dental Radiography and Imaging
- Obstructive Sleep Apnea Research
- Neuroscience and Neuropharmacology Research
- Vestibular and auditory disorders
- Child Nutrition and Feeding Issues
- Pain Management and Placebo Effect
- Olfactory and Sensory Function Studies
- Neuroscience of respiration and sleep
- Empathy and Medical Education
- Neurobiology of Language and Bilingualism
- Stress Responses and Cortisol
- Oropharyngeal Anatomy and Pathologies
University of Toronto
2011-2024
Statistical Research (United States)
2023
Tel Aviv University
1996
Hebrew University of Jerusalem
1993
Abstract Loss of teeth is associated with changes in somatosensory inputs and altered patterns mastication, but it unclear whether tooth loss motor representations within face sensorimotor cortex rats. We used intracortical microstimulation (ICMS) recordings cortically evoked muscle electromyographic (EMG) activities to test occur the ICMS‐defined left right jaw muscles [masseter, anterior digastric (LAD, RAD)] tongue [genioglossus (GG)] cytoarchitectonically defined primary (face‐M1)...
Building upon our recently developed conceptual definition of oral frailty (the age-related functional decline orofacial structures), this e-Delphi study aims to develop an operational by identifying its components.
Modification to the dental occlusion may alter oral sensorimotor functions. Restorative treatments aim restore functions; however, it is unclear why some patients fail adapt restoration and remain with complaints. The face primary motor cortex (face-M1) involved in generation control of orofacial movements. Altered sensory inputs or function can induce face-M1 neuroplasticity. We took advantage continuous eruption incisors Sprague-Dawley rats used intracortical microstimulation (ICMS) map...
Tooth loss is associated with altered sensory, motor, cognitive and emotional functions. These changes vary highly in the population are accompanied by structural functional brain regions mediating these It unclear to what extent this variability behavior function caused genetic and/or environmental determinants which undergo plasticity that mediates changes. Thus, overall goal of our research program identify variants control following tooth loss. As a step towards goal, here aim was...
Tooth loss is common, and exploring the neuroplastic capacity of face primary motor cortex (face-M1) adjacent somatosensory (face-S1) crucial for understanding how subjects adapt to tooth their prosthetic replacement. The aim was test if functional reorganization jaw tongue representations in rat face-M1 face-S1 occurs following extraction, subsequent dental implant placement can reverse this neuroplasticity. Rats (n = 22) had right maxillary molar teeth extracted under local general...
ABSTRACT Orthodontic tooth movement (OTM) causes transient pain and changes in the dental occlusion that may lead to altered somatosensory inputs patterns of mastication. This study used intracortical microstimulation (ICMS) electromyographic (EMG) recordings test whether neuroplastic occur ICMS‐defined motor representations left right anterior digastric (LAD, RAD), masseter, buccinator, genioglossus (GG) muscles within rat's face primary cortex (face‐M1) adjacent (face‐S1) during OTM....
Jaw and tongue motor alterations may occur following changes in food consistency, but whether such are associated with re-organization of representations within the facial sensorimotor cortex is unclear. We used intracortical microstimulation (ICMS) recordings evoked electromyographic responses to determine jaw (anterior digastric) (genioglossus) histologically defined face primary (face-M1) adjacent somatosensory (face-S1) rats fed hard (N = 6) or soft diet for 2 3 weeks. ICMS from an...
Abstract: A computer‐assisted measurement technique for measuring bone levels proximal (mesial and distal) to oral implants imaged on standardized intraoral radiographs offers promise accuracy reliability. There were no differences between measurements made directly from placed in a dry mandible those resulting the technique. In addition, there of vivo using microscope computer techniques. The had low intra‐ inter‐operator variability, operators found fewer “unreadable” sites compared
Neuropathic orofacial pain conditions represent a challenge to diagnose and treat. Natural substances are promising therapeutic options for the control of pain. This study aimed examine whether (−)-α-bisabolol (BISA), natural terpene, can attenuate nociceptive behaviour central sensitisation in rodent model trigeminal neuropathic Infraorbital nerve transection (IONX) or sham operation was performed adult male rats. Head withdrawal thresholds as measure facial mechanical sensitivity were...
The vast and complex array of orofacial muscles movements necessitate sophisticated adaptive neural circuits providing for their control integration with other motor behaviours. It has become apparent from anatomical, electrophysiological, imaging behavioural studies the face sensorimotor cortex in humans or laboratory animals that primary (MI) somatosensory (SI) make important contributions not only to elemental learned but also mastication swallowing past have been largely attributed...
To use a micro-computed tomography (micro-CT) to quantify bone healing at maxillary first molar extraction sites, and test the hypothesis that is impaired in CD24-knockout mice as compared with wild-type C57BL/6J mice.Under ketamine-xylazine general anaesthesia, had either of right tooth or sham operation. Mice were sacrificed 1 (n = 12/group), 2 6/group) 4 weeks postoperatively. The maxillae was disected. Micro-CT used differences microstructural features extrction between...
A young female patient suffering from Satoyoshi syndrome had the first characteristic signs and symptoms of hair loss progressive spontaneous intermittent painful spasms limb muscles at age 6.5 years. Thereafter, she developed chronic diarrhea, amenorrhea, skeletal deformities. In orofacial region, suffered masseter (jaw closing) muscles, tooth loss, degeneration mandibular condyles. Treatment with steroids provision complete dentures improved symptoms. Early diagnosis timely...