A5008218437- Metal complexes synthesis and properties
- Protein Interaction Studies and Fluorescence Analysis
- Lanthanide and Transition Metal Complexes
- Free Radicals and Antioxidants
- Drug Transport and Resistance Mechanisms
- Organometallic Compounds Synthesis and Characterization
- Surfactants and Colloidal Systems
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Electrochemical Analysis and Applications
- DNA and Nucleic Acid Chemistry
- Computational Drug Discovery Methods
- Adsorption and biosorption for pollutant removal
- Nanoparticle-Based Drug Delivery
- Ferrocene Chemistry and Applications
- Crystallography and molecular interactions
- Nanomaterials for catalytic reactions
- Oxidative Organic Chemistry Reactions
- Molecular Sensors and Ion Detection
- Magnetism in coordination complexes
- Crystal structures of chemical compounds
- Enzyme Structure and Function
Zabol University
2016-2025
Zahedan University of Medical Sciences
2009-2018
University of Shahrood
2018
University of Sistan and Baluchestan
2014
Two new gold(III) complexes, [AuL 1 ]Cl 3 , A and 2 B were synthesized characterized. DFT calculations showed square planar geometry for both complexes. Antioxidant results that the ability of compounds to inhibit DPPH• is as follows: > L . The anticancer assay complexes have growth HCT116 colon cancer cell lines, but shows a relatively better effect than cisplatin. interaction effects on activity structure bovine liver catalase (BLC) investigated by spectroscopic techniques molecular...
Human serum albumin (HSA) is a globular and monomeric protein in plasma that transports many drugs compounds. Binding of some to HSA can lead changes its stability biological function. We investigated the binding interactions between erlotinib hydrochloride (Erlo) HSA. Erlo used treat lung, pancreatic, other cancers. Experimental data showed fluorescence emission was quenched by using static quenching mechanism. The calculation constant, Kb (1.57 × 105 M-1 at 300 K), confirmed existence...
ABSTRACT Schiff bases are introduced as versatile pharmacophores for the design and development of various bioactive compounds. Oxime‐based base ligands form an important flexible class that have attracted attention due to their wide applications in fields. Here, novel 3‐(2‐hydroxyphenyl‐imino)butan‐2‐one oxime, ( HPIO ) Zn(II) complexes derived from it, [Zn(bpy)(HPIO)](NO 3 2 , C1 (bpy = 2,2′‐bipyridine) [Zn(HPIO) ]Cl C2 were synthesized characterized. Theoretical studies showed both...
In this work, we present the development of a novel photocatalyst system based on graphitic carbon nitride (g-C3N4) nanosheets decorated with Rhodium(III) organometallic complex, denoted as Rh(III)/g-C3N4, in Selective Oxidation alcohols. The were synthesized from OAT (Oxi Amino Triazine) waste material which is by-product melamine unit North Khorasan Petrochemical Company. rhodium precursors employed 5-methyl-5-(2-pyridyl)-2,4-imidazolidenedione and K3[RhCl6], formed Rh(III) nanoparticles...
<title>Abstract</title> A complex formulized as [Cu(dmpn)<sub>2</sub>(OH<sub>2</sub>)][Cu<sub>2</sub>(DPA)<sub>4</sub>µ-Cu(dmpn)<sub>2</sub>] (<bold>1</bold>), where dmpn is 2,2<sup>׳</sup>-dimethyl-1,3-diaminepropane and DPA dipicolinic acid (H<sub>2</sub>dipic), was synthesized characterized by X-ray crystallography, conductivity measurement, thermogravimetric (TG) analysis spectroscopic methods (IR, UV-Vis). The initial <italic>in vitro</italic> cytotoxic activity of (<bold>1</bold>)...
Abstract The study of protein‐drug interactions has become important in describing drug properties. Favipiravir ( Fav ) is an RNA polymerase inhibitor used to treat a wide range influenza viruses. This drug, which taken orally, can be quickly and widely absorbed the body. Here, interaction with two Fe‐related proteins, Catalase (CAT) Transferrin (TF), was investigated by spectroscopic molecular docking methods. results showed that strongly interact Fe‐proteins quench their intrinsic...
In this study, a cytotoxic Pt(IV) complex [Pt(5,5′-dmbpy)Cl4 (5,5′-dmbpy is 5,5′-dimethyl-2,2′-bipyridine) was selected to investigate its affinity human serum albumin (HSA) by spectroscopy and molecular docking methods. This has bidentate nitrogen donor ligand with four chloride anions attached metal in distorted octahedral environment. The fluorescence data showed quench the intrinsic of HSA through static quenching mechanism. binding constant (Kb) number sites (n) were obtained based on...
In this study, a new lanthanum (III)-amino acid complex utilizing cysteine has been synthesized and characterized. The anticancer activities of the prepared La(III) against MCF-7 cell lines were studied. Results MTT assay showed that at all three incubation times, cytotoxic effect on breast cancer displays time- dose-dependent inhibitory effects. interactions with two whey proteins (bovine serum albumin, BSA, Bovine β-lactoglobulin, βLG) have explored by using spectroscopic molecular dicking...