PURPOSE: To determine the safety and efficacy of combination chimeric anti-CD20 antibody Rituxan (rituximab, IDEC-C2B8; Genentech Inc, South San Francisco, CA) cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) chemotherapy in patients with aggressive non-Hodgkin’s lymphoma (NHL). PATIENTS AND METHODS: Thirty-three previously untreated advanced B-cell NHL received six infusions (375 mg/m 2 per dose) on day 1 each cycle doses CHOP given 3 cycle. RESULTS: The ORR by investigator...

An important aspect of qualitative research is reaching saturation—loosely, a point at which observing more data will not lead to discovery information related the questions. However, there has been no validated means objectively establishing saturation. This article proposes novel quantitative approach measuring thematic saturation based on sound statistical model. The model two sets from different projects involving interviews, focus groups, and literature surveys. proposed provides...

Skin is the outermost layer of human body which regulates temperature and protects from abrasion water loss.The Young's Modulus skin measured as a ratio stress applied to in vitro or vivo over deformation.Skin found be highly anisotropic dependent on orientation with respect Langer's lines, where highest value seen parallel orientation, can twice perpendicular values.Young's decreases up three orders magnitude hydration.An inverse relationship between skin's thickness observed.It concluded...

Central arterial pressure is a better predictor of adverse cardiovascular outcomes than brachial blood pressure, but noninvasive measurement by applanation tonometry technically demanding.Pulsecor R6.5 novel device adapted from standard sphygmomanometer which estimates the central aortic analysis low-frequency suprasystolic waveforms at occluded artery. A physics-based model, simulates system using elastic, thin-walled tube elements and Navier-Stokes equations, used to calculate flow...

Correct identification of the fundamental heart sounds is an important step in identifying cycle stages. Heart valve pathologies can cause abnormal or extra sounds, and distinguishing feature between different timing these cycle. In design understandable sound analysis system, segmentation indispensable step. this study classification using continuous wavelet transform (CWT) scalograms convolutional neural networks (CNN) investigated. Classification first second produced by Morse analytic...

Continuous blood pressure (BP) measurement is vital in monitoring patients' health with a high risk of cardiovascular disease. The complex and dynamic nature the system can influence BP through many factors, such as cardiac output, vessel wall elasticity, circulated volume, peripheral resistance, respiration, emotional behavior. Yet, traditional methods continuously estimating are cumbersome inefficient. This paper presents novel hybrid model by integrating convolutional neural network (CNN)...

Non-invasive techniques have become increasingly vital in modern medicine, providing valuable diagnostic information without invasive procedures. These encompass a diverse range of procedures, including imaging scans, blood tests, urine and genetic testing, enabling the investigation various conditions device insertion. In contrast to conventional methods, non-invasive diagnostics numerous advantages, reduced complications, shorter recovery times, improved patient comfort, lower costs. As...

Recent advancement in wearable and robot-assisted healthcare technology gives rise to the demand for smart interfaces that allow more efficient human-machine interaction. In this paper, a hydrogel-based soft sensor subtle touch detection is proposed. Adopting working principle of biomedical imaging known as electrical impedance tomography (EIT), produces images display conductivity distribution its sensitive region enable detection. The was made from natural gelatin hydrogel whose...

Abstract The growing popularity of smart healthcare and novel innovations in human movement monitoring systems open doors for diagnosing various health conditions, including neurological disorders, musculoskeletal system problems, mobility limitations associated with aging, the oversight rehabilitation programs. This paper discusses technical challenges, potential applications, prospects conceptual Digital Twin (DT) Technology IoT-based systems, underscoring its role revolutionizing...

Abstract The monitoring of electrocardiogram (ECG) signals is crucial for both cardiac health and mental state assessment. Traditional ECG methods rely on chest electrodes; however, they pose challenges individuals with injuries or burns can cause discomfort over extended use. Capacitive electrodes offer a non-contact method, which particularly beneficial wearable applications, providing comfortable feasible alternative long-term Findings suggest that neck-based achieve effective signal...

Fourteen cats received either daily prednisolone (4.4 mg/kg per os [PO]) or dexamethasone (0.55 PO) for 56 days. These doses were clinically equipotent. Serum fructosamine and urine glucose measured on days 0, 28, 56. Insulin sensitivity, tolerance, peak insulin secretion in each group prior to at the end of courses glucocorticoid administration. On day 56, prevalence glucosuria was significantly greater (P=0.027), a trend seen toward concentrations (P=0.083) dexamethasone-treated compared...

Fourteen cats were given immunosuppressive doses of either prednisolone (4·4 mg/kg/day) or dexamethasone (0·55 for 56 days. Complete blood counts, serum biochemistry profiles and urinalyses performed on days 0 56, liver biopsies taken laparoscopically day because evidence hepatic disease the profiles. There significant increases in cats' mean white cell neutrophil counts monocyte decreases their lymphocyte eosinophil counts. consistent concentrations albumin, glucose, triglycerides...

Lowe, A., A. C. Rogers, and K. L. Durrant. 2014. Effect of human disturbance on long-term habitat use breeding success the European Nightjar, Caprimulgus europaeus. Avian Conservation Ecology 9(2): 6.http://dx.doi.org/10.5751/ACE-00690-090206