Carolina Agudelo

ORCID: 0000-0002-0624-3551
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About
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Research Areas
  • Advanced Glycation End Products research
  • Immune responses and vaccinations
  • Food Security and Health in Diverse Populations
  • Clostridium difficile and Clostridium perfringens research
  • Natural Antidiabetic Agents Studies
  • Inflammasome and immune disorders
  • Microbial Metabolism and Applications
  • Immune Cell Function and Interaction
  • Antimicrobial Resistance in Staphylococcus
  • Gut microbiota and health
  • Tea Polyphenols and Effects

University of California, Berkeley
2024-2025

University of Florida
2021

Abstract Background Infection with the COVID-19-causing pathogen SARS-CoV-2 is associated disruption in human gut microbiome. The microbiome enables protection against diverse pathogens and exhibits dysbiosis during infectious autoimmune disease. Studies based United States China have found that severe COVID-19 cases altered composition when compared to mild cases. We present first study investigate of a population from Sub-Saharan Africa. Given impact geography cultural traditions on...

10.1186/s13099-025-00678-4 article EN cc-by Gut Pathogens 2025-02-04

Background: Infection with the COVID-19-causing pathogen SARS-CoV-2 is associated disruption in human gut microbiome. The microbiome enables protection against diverse pathogens and exhibits dysbiosis during infectious autoimmune disease. Studies based United States China have found that severe COVID-19 cases altered composition when compared to mild cases. We present first study investigate of a population from Sub-Saharan Africa. Given impact geography cultural traditions on composition,...

10.1101/2024.09.28.24314457 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2024-09-30

Abstract Infected macrophages transition into aerobic glycolysis, a metabolic program crucial for control of bacterial infection. However, antimicrobial mechanisms supported by glycolysis are unclear. Methylglyoxal is highly toxic aldehyde that modifies proteins and DNA produced as side-product glycolysis. Here we show despite the toxicity this aldehyde, infected generate high levels methylglyoxal during while downregulating detoxification system. We use targeted mutations in mice to...

10.1101/2024.11.03.621721 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-11-03
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