Xiaomin Chen

ORCID: 0000-0002-0633-2984
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About
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Research Areas
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Advanced Chemical Sensor Technologies
  • Advanced Fluorescence Microscopy Techniques
  • Chronic Kidney Disease and Diabetes
  • Cancer, Hypoxia, and Metabolism
  • Adrenal and Paraganglionic Tumors
  • Hormonal Regulation and Hypertension
  • Advanced Glycation End Products research
  • Microbial Metabolites in Food Biotechnology
  • Advanced Electron Microscopy Techniques and Applications
  • Groundwater and Isotope Geochemistry
  • Helicobacter pylori-related gastroenterology studies
  • RNA Research and Splicing
  • Biochemical Analysis and Sensing Techniques
  • Diabetes Treatment and Management
  • Monoclonal and Polyclonal Antibodies Research
  • Isotope Analysis in Ecology
  • Genomics and Phylogenetic Studies

Zhongshan Hospital of Xiamen University
2023-2024

University of Electronic Science and Technology of China
2024

University of Chinese Academy of Sciences
2013-2021

Institute of Biophysics
2021

Chinese Academy of Sciences
2021

Abstract Small proteins specifically refer to consisting of less than 100 amino acids translated from small open reading frames (sORFs), which were usually missed in previous genome annotation. The significance has been revealed current years, along with the discovery their diverse functions. However, systematic annotation is still insufficient. SmProt was specially developed provide valuable information on for scientific community. Here we present update SmProt, emphasizes reliability...

10.1016/j.gpb.2021.09.002 article EN cc-by-nc-nd Genomics Proteomics & Bioinformatics 2021-08-01

Abstract Small proteins specifically refer to consisting of less than 100 amino acids translated from small open reading frames (sORFs), which were usually missed in previous genome annotation. The significance has been revealed current years, along with the discovery their diverse functions. However, systematic annotation is still insufficient. SmProt was specially developed provide valuable information on for scientific community. Here we present update SmProt, emphasizes reliability...

10.1101/2021.04.29.441405 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-04-30

<title>Abstract</title> Aims To investigate the potential effects of SGLT2 inhibitor empagliflozin on renal inflammatory pathways in diabetic rats. Materials and Methods Sprague Dawley (SD) rats model was established by intraperitoneal injection streptozotocin (STZ, 35 mg/kg) after 4-week high-sugar high-fat diet intervention. Rats were randomly assigned to three groups: normal control (NC), diabetes with saline (DM + NS), EMP). Empagliflozin (10mg/kg/day) or equivalent volume administered...

10.21203/rs.3.rs-4749865/v1 preprint EN cc-by Research Square (Research Square) 2024-08-13

Some microbes are referred to as model organisms because they easy study in the laboratory and hold ability retain their characteristics during DNA replication, transcription, other fundamental processes. Studying these living cells via single-molecule imaging allows us better understand processes at highly improved spatiotemporal resolution. Single particle tracking photoactivated localization microscopy (sptPALM) is a robust tool for detecting positions motions of individual molecules with...

10.52601/bpr.2024.240028 article EN cc-by Biophysics Reports 2024-08-28

Adrenocortical carcinoma (ACC) is a malignant with an extremely poor prognosis, and its pathogenesis remains to be understood date, necessitating further investigation. This study aims discover biomarkers potential therapeutic agents for ACC through bioinformatics, enhancing clinical diagnosis treatment strategies. Differentially expressed genes (DEGs) between normal adrenal cortex were screened out from the GSE19750 GSE90713 datasets available in GEO database. An online Venn diagram tool...

10.1055/a-2209-0771 article EN Hormone and Metabolic Research 2023-12-18
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