A5051714016- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Retinal Imaging and Analysis
- Respiratory viral infections research
- Retinal Diseases and Treatments
- Diet and metabolism studies
- Antenna Design and Analysis
- Antenna Design and Optimization
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Radio Wave Propagation Studies
- Pneumonia and Respiratory Infections
- Colorectal Cancer Surgical Treatments
- Pharmacological Receptor Mechanisms and Effects
- Influenza Virus Research Studies
- Neuropeptides and Animal Physiology
- Liver Disease and Transplantation
- Antifungal resistance and susceptibility
- Cardiovascular Health and Disease Prevention
- Liver Disease Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Hormonal Regulation and Hypertension
- Viral Infections and Immunology Research
- Dietary Effects on Health
Qingdao University
2015-2025
Affiliated Hospital of Qingdao University
2023-2025
Beijing University of Posts and Telecommunications
2025
State Key Laboratory of Networking and Switching Technology
2025
China-Japan Friendship Hospital
2020-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Beijing Chao-Yang Hospital
2012-2024
Capital Medical University
2012-2024
China National Petroleum Corporation (China)
2024
Center for Life Sciences
2020-2024
<b>Objective</b> To characterise the complete case series of influenza A/H7N9 infections as 27 May 2013, detected by China's national sentinel surveillance system for influenza-like illness. <b>Design</b> Case series. <b>Setting</b> Outpatient clinics and emergency departments 554 hospitals across 31 provinces in mainland China. <b>Cases</b> Infected individuals were identified through cross-referencing people who had laboratory confirmed infection with illness, where patients meeting World...
Aims. Hashimoto’s thyroiditis (HT), a type of autoimmune disease, occurs due to genetic predisposition and environmental factors. It is well known that thyroid function may affect the gut microbiota. However, composition microbiota in HT patients with different status has been less highlighted. Therefore, we focused on alterations euthyroidism hypothyroidism. Methods. We performed cross-sectional study, including 45 euthyroidism, 18 hypothyroidism, 34 healthy controls. Fecal samples were...
Abstract As a common chronic metabolic disease, the development of diabetes mellitus (DM) may also be accompanied by liver damage and inflammatory disorders. Sitagliptin is an inhibitor dipeptidyl peptidase-4 (DPP4, known as CD26), which clinically used for DM treatment. However, mechanism sitagliptin’s efficiency in diseases largely unknown. In this study, mice suffering from streptozotocin (STZ) exhibit elevated DPP4 expression activity, well injury phenotype, whereas specifically...
Accumulating evidence has indicated that alterations of gut microbiota have been involved in various metabolic diseases. Orlistat, a reversible inhibitor pancreatic and gastric lipase, beneficial effects on weight loss metabolism. However, the effect orlistat composition remains unclear.We aimed to explore high-fat diet (HFD) fed C57BL/6J obese mice.C57BL/6J mice were randomly divided into three groups: control (NCD), HFD, HFD + (ORL). Mice NCD group chow diet, while other groups for 6...
Abstract Background/purpose Overt hepatic encephalopathy (HE) risk should be preoperatively predicted to identify patients suitable for curative transjugular intrahepatic portosystemic shunt (TIPS) instead of palliative treatments. Methods A total 185 who underwent TIPS procedure were randomised (130 in the training dataset and 55 validation dataset). Clinical factors imaging characteristics assessed. Three different models established by logistic regression analyses based on clinical (Model...
Colorectal cancer is a common malignant tumor of the digestive tract. It frequently occurs at junction rectum and sigmoid colon. characterized by high mortality poor prognosis. Bcl-2 interacting mediator cell death (BIM) plays role in regulation proliferation apoptosis, involves pathogenesis colorectal cancer. The transcription factor forkhead, O subfamily 3a (FoxO3a) BIM expression associated to Bioinformatics analysis suggests that there targeted relationship between FoxO3a microRNA-223...
Abstract The incidence and mortality of colorectal carcinoma are rising in young adults. This population‐based propensity matching study aimed to compare long‐term oncological outcomes local excision with radical resection for early localized cancer ( CRC ) patients without preoperative chemoradiotherapy. Patients under 45 years old T1 colon or rectal adenocarcinoma who underwent were included from the Surveillance, Epidemiology, End Results SEER database between 1998 2014. Survival curves...
Introduction:The aim of the study was to investigate significance factors associated with minimal hepatic encephalopathy (MHE) in cirrhotic patients.Material and methods: Between September 2012 August 2013, 60 patients, including MHE non-MHE (NMHE) were included study.Associated clinical analyzed see if they significantly different between patients.Upon identifying showing differences, we applied multivariate regression analysis further decide which most significant ones differentiate from...
As the standard therapy for pancreatic cancer, gemcitabine shows limited efficacy in cancer patients because of chemoresistance. Aberrant expression Bmi1 has been reported to activate multiple growth-regulatory pathways and confer anti-apoptotic abilities many cells. However, role response cells towards resistance remains elusive. In this study, we found that certain dose treatment induced Knockdown enhanced ROS production promoted cytotoxic effect gemcitabine. The increased oxidative stress...
Introduction. Brachial–ankle pulse wave velocity (baPWV), an indicator of arterial stiffness, has been demonstrated to be associated with type 2 diabetes mellitus (T2DM) and its vascular complications. This study was aimed at investigating the correlations baPWV both presence severity diabetic retinopathy (DR) baseline exploring predictive role in new onset/progression DR follow-up analysis. Methods. The prospective cohort recruited 2,473 Chinese patients T2DM, whom 663 participants were...
Background and Aims: This study is aimed at investigating the potential correlation of thyroid hormone sensitivity with visceral fat area (VFA), subcutaneous (SFA), body mass index (BMI) among euthyroid type 2 diabetes mellitus (T2DM) subjects.Methods: Thyroid indices were calculated by feedback quantile–based (TFQI), TSH (TSHI), thyrotropin thyroxine resistance (TT4RI), free (fT4)/free triiodothyronine (fT3) ratio. These then categorized into quartiles for analysis. The outcomes change...
The decidua plays a crucial role in providing structural and trophic support to the developing conceptus before placentation. Following embryo attachment, embryonic components intimately interact with decidual tissue. While evidence indicates participation of embryo-derived factors crosstalk uterus, extent their impact on post-implantation development requires further investigation. Here, we utilize transgenic mouse models selectively eliminate primary trophoblast giant cells (pTGCs), that...
No predictive model for lymph node metastasis (LNM) of superficial esophagogastric junction (EGJ) cancer exists. This study aimed to evaluate incidence, identify risk factors, and develop a nomogram LNM in patients with EGJ cancers.Data were extracted from the Surveillance, Epidemiology, End Results database development internal validation. Another data set was obtained two hospitals external A developed based on independent factors that resulted multivariate logistic regression analysis....