A5100725473- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Medical and Biological Ozone Research
- Organ Transplantation Techniques and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- Hydrogen's biological and therapeutic effects
- Central Venous Catheters and Hemodialysis
- Aortic aneurysm repair treatments
- Therapeutic Uses of Natural Elements
- Vascular Procedures and Complications
- Musculoskeletal pain and rehabilitation
- Cancer-related gene regulation
- Acute Lymphoblastic Leukemia research
- Vascular Malformations and Hemangiomas
- Ferroptosis and cancer prognosis
- Gynecological conditions and treatments
- Vascular Malformations Diagnosis and Treatment
- Air Quality and Health Impacts
- Neuroblastoma Research and Treatments
- Nanoparticle-Based Drug Delivery
- Aortic Disease and Treatment Approaches
- Advanced Radiotherapy Techniques
Chinese PLA General Hospital
2014-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Southern Medical University
2010-2023
Changzhi Medical College
2022-2023
Nanfang Hospital
2010-2023
Zhuhai People's Hospital
2023
ShenZhen People’s Hospital
2023
Zhongshan People's Hospital
2023
Jinan University
2023
Zhejiang University
2022
Hepatocellular carcinoma (HCC) often arises in the setting of chronic inflammation with multiple inhibitory immune signals. V-domain Ig suppressor T cell activation (VISTA) is identified as a novel negative checkpoint regulator. This study sought to determine expression and prognostic value VISTA HCC classify tumor microenvironments (TMEs) based on CD8+ tumor-infiltrating lymphocytes (TILs).The CD8 proteins was assessed 183 tissue microarrays (TMAs) by immunohistochemistry (IHC). CD8A mRNA...
Embolization (utilizing embolic materials to block blood vessels) has been considered one of the most promising strategies for clinical disease treatments. However, existing have poor embolization effectiveness, posing a great challenge highly efficient embolization. In this study, we construct Janus particle-engineered structural lipiodol droplets by programming self-assembly particles at lipiodol-water interface. As result, achieve renal in rabbits. The obtained exhibit excellent...
BACKGROUNDSome patients with hepatocellular carcinoma (HCC) are more likely to experience disease progression despite continuous transarterial chemoembolization (TACE), which is called TACE refractoriness.At present, it still difficult predict refractoriness, although some models/scoring systems have been developed.At radiological-based radiomics models successfully applied cancer patient prognosis. AIMTo develop and validate a computed tomography (CT)-based nomogram for the pre-treatment...
The objective of our study was to evaluate the efficacy and safety percutaneous intralesional injection under fluoroscopy with pingyangmycin Lipiodol emulsion (PLE) for treatment orbital venous malformations.. This is a retrospective analysis 19 consecutive patients distensible malformations. Of patients, two had diffuse lesions. These presented proptosis (n = 19), pain swelling 11), reduction in visual acuity 4), diplopia 2), disk 5), motility disturbance 3).All underwent technically...
Abstract Background/purpose Overt hepatic encephalopathy (HE) risk should be preoperatively predicted to identify patients suitable for curative transjugular intrahepatic portosystemic shunt (TIPS) instead of palliative treatments. Methods A total 185 who underwent TIPS procedure were randomised (130 in the training dataset and 55 validation dataset). Clinical factors imaging characteristics assessed. Three different models established by logistic regression analyses based on clinical (Model...
Background Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor outcomes and high recurrence. Disulfidptosis, novel form of programmed cell death driven by aberrant disulfide bonds F-actin collapse, provides insights into cancer progression treatment. Methods We investigated the correlation network prognostic values disulfidptosis-related genes (DRGs) in AML. Unsupervised clustering was performed to reveal distinct AML subtypes. implemented differential analysis enrichment...
Purpose To evaluate the clinical value of CT-guided radiofrequency ablation (RFA) in diagnosis and treatment pulmonary metastases under optical electromagnetic navigation.
This study aimed to assess the feasibility, safety, and accuracy of a low-dose CT fluoroscopy-guided remote-controlled robotic real-time puncture procedure.
Models should be developed to assist choice between liver resection (LR) and transarterial chemoembolization (TACE) for hepatocellular carcinoma.After separating 520 cases from 5 hospitals into training (n = 302) validation 218) data sets, we weighted the control baseline difference ensured causal effect treatments (LR TACE) estimated progression-free survival (PFS) difference. A noninvasive PFS model was constructed with clinical factors, radiological characteristics, radiomic features. We...
Hepatocellular carcinoma (HCC) is one of the deadliest cancers worldwide. High-mobility group box 1 (HMGB1), a highly conserved chromosome protein, considered as potential therapeutic target and novel biomarker because its regulation in proliferation metastasis HCC. Ozone has been shown to be beneficial treatment cancer. The objective this study was explore effects molecular mechanism ozonated water on proliferation, migration, invasion BEL7402 HCC cells.We assessed cell using CCK-8 assay...
Transarterial chemoembolization (TACE) is one of the most commonly used treatments for hepatocellular carcinoma (HCC); however, poor stability emulsified chemotherapy drugs by iodinated oil always leads to serious systemic cytotoxicity. Herein, a composite hydrogel Epi/Etpoil@MC/XG was proposed stably distributing ethiodized poppyseed (Etpoil) and epirubicin (Epi) in blend methylcellulose (MC) xanthan gum (XG). Benefiting from its adjusted thermo-responsive injectable properties, has been...
The effectiveness of COVID-19 vaccines wanes over time and the emergence SARS-CoV-2 Omicron variant led to accelerated expansion efforts for booster vaccination. However, effect contribution vaccination with inactivated remain be evaluated. We conducted a retrospective close contacts cohort study analyze epidemiological characteristics infection risk, evaluate against infection, symptomatic COVID-19, pneumonia during outbreaks BA.2 from 1 February 31 July 2022 in Guangdong, China. A total...
Background/Aims: Early hepatic encephalopathy (HE) is one of the most common complications developed after undergoing transjugular intrahepatic portosystemic shunt (TIPS).Hence, its early prevention and treatment are important.This study aimed at establishing a model to predict post-TIPS HE. Materials Methods: Clinical data 262 patients who underwent TIPS procedure was analyzed retrospectively.Patients were divided into HE non-early groups, based on presence within 3 months TIPS.About 70%...
Abstract Objective Fear of progression (FoP) is a common psychosocial problem among adult cancer patients, but data on parents children undergoing treatment are scarce. This study aimed to determine the prevalence FoP in and explore associated factors. Methods Overall, 285 were recruited from three general hospitals China. was assessed using Chinese version Progression Questionnaire‐parent (FoP‐Q‐SF/PR). Other questionnaires included Self‐Compassion Scale, Pittsburgh Sleep Quality Index,...
Abstract Stent implantation is a commonly used palliative treatment for alleviating stenosis in advanced esophageal cancer. However, tissue proliferation induced by stent and continuous tumor growth can easily lead to restenosis. Therefore, functional stents are required relieve while inhibiting growth, thereby extending the patency. Currently, no ideal available. Here, iodine‐125 ( 125 I) nuclides encapsulated into nickel–titanium alloy (NiTi) tube develop novel temperature‐memory spiral...
Ozone therapy has been gradually accepted by doctors in various fields because it safe, convenient, and inexpensive since the twentieth century. It used treatment of diseases with satisfactory results, especially application interventional surgery. For lumbar disc herniation, knee osteoarthritis, tissue ischemia-reperfusion after revascularization, stroke, cancer, ozone can improve efficacy surgery reduce postoperative acute chronic complications. Prospects underlying mechanisms need further...
For timely treatment of extrahepatic metastasis and macrovascular invasion (aggressive progressive disease [PD]) in hepatocellular carcinoma, models aimed at stratifying the risks subsequent aggressive PD should be constructed.After dividing 332 patients from five hospitals into training (n = 236) validation 96) datasets, non-invasive models, including clinical/semantic factors (ModelCS), deep learning radiomics (ModelD), both (ModelCSD), were constructed to stratify according risk PD. We...