About
Contact & Profiles
A5099131084
Research Areas
- Apelin-related biomedical research
- Lipid metabolism and disorders
- Axon Guidance and Neuronal Signaling
Heinrich Heine University Düsseldorf
2024
Prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty disease, increases worldwide and associates with type 2 diabetes other cardiometabolic diseases. Here we demonstrate that Sema3a is elevated in sinusoidal endothelial cells animal models for obesity, MASLD. In primary human cells, saturated acids induce expression SEMA3A, loss a single allele sufficient to reduce hepatic fat content diet-induced obese mice. We show...
10.1038/s44161-024-00487-z
article
EN
cc-by
Nature Cardiovascular Research
2024-06-14
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