Kamil Jurczyszyn

ORCID: 0000-0002-0667-7261
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About
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Research Areas
  • Photodynamic Therapy Research Studies
  • Oral Health Pathology and Treatment
  • Nanoplatforms for cancer theranostics
  • Dental materials and restorations
  • Oral and Maxillofacial Pathology
  • Laser Applications in Dentistry and Medicine
  • Nonmelanoma Skin Cancer Studies
  • Dental Implant Techniques and Outcomes
  • Salivary Gland Tumors Diagnosis and Treatment
  • Orthodontics and Dentofacial Orthopedics
  • Bone Tissue Engineering Materials
  • Dental Radiography and Imaging
  • Cutaneous Melanoma Detection and Management
  • AI in cancer detection
  • Porphyrin and Phthalocyanine Chemistry
  • Urological Disorders and Treatments
  • Cancer-related Molecular Pathways
  • Dermatologic Treatments and Research
  • Endodontics and Root Canal Treatments
  • Skin Protection and Aging
  • Genital Health and Disease
  • Retinoids in leukemia and cellular processes
  • Dental Erosion and Treatment
  • Morphological variations and asymmetry
  • Dental Anxiety and Anesthesia Techniques

Wroclaw Medical University
2016-2025

University of Wrocław
2022-2023

Thanks to the continuous development of light-curing resin composites it is now possible print permanent single-tooth restorations. The purpose this study was compare for milling -Gandio Blocks (GR), Brilliant Crios (CR) and Enamic (EN) with composite 3D printing—Varseo Smile Crown plus (VSC). Three-point bending used measure flexural strength (σf) modulus (Ef). microhardness measured using a Vickers method, while fractographic, microstructural, texture fractal dimension (FD) analyses were...

10.3390/ma14174919 article EN Materials 2021-08-29

Three-dimensional printing is finding increasing applications in today’s world. Due to the accuracy and possibility of rapid production, CAD/CAM (computer-aided design/computer-aided manufacturing) technology has become most desired approach preparation elements, especially medicine dentistry. This study aimed compare biomechanical properties, fractal dimension (FD), texture three selected materials used for 3D Three biomaterials were evaluated. The subjected compression test. Then, their...

10.3390/polym15071772 article EN Polymers 2023-04-02

Background: The study aimed to compare the effectiveness of photodynamic therapy (PDT) and topical clobetasol in treating oral lichen planus (OLP). To address absence commercially available drug carriers, innovative proprietary solutions were developed. These carriers designed enhance therapies: one for photosensitizer reduce its contact time with mucosa, another steroid prolong duration. Methods: A randomized, single-blind clinical trial lasting three months was conducted on 29 patients...

10.3390/jcm14030681 article EN Journal of Clinical Medicine 2025-01-21

Background/Objectives: The blood vessel network can be used as a potential marker of general health. In the oral cavity, it is possible to diagnose systemic diseases manifestations many metabolic, cardiovascular, hematological, and autoimmune may represent in lingual tissue. Methods: present study, fractal dimension analysis (FD) vessels tongue was applied physiology well pathology cardiovascular diseases. This study conducted for old men women aged 68–95 years. Intraoral photography lower...

10.3390/jcm14051429 article EN Journal of Clinical Medicine 2025-02-20

Background:Common skin tumors like basal- and squamous-cell carcinoma present a serious problem in modern medicine. Exposure to ultraviolet solar radiation is the main cause of these lesions. Since application Aldara® PDT separately well documented, we decided use both methods together.The aim our study was evaluate effectiveness local photodynamic therapy supplemented with topical basal-cell carcinoma.Material/Methods:Thirty-four patients ages 50 68 years were enrolled trial underwent...

10.12659/msm.882449 article EN Medical Science Monitor 2012-01-01

Purpose: to assess the effect of photobiomodulation (PBM) on human gingival fibroblast proliferation. Methods: The study was conducted using primary cell cultures fibroblasts collected from systemically healthy donors. Three different laser types, Nd:YAG (1064 nm), infrared diode (980 and prototype led emitting 405, 450, 635 nm were used irradiate fibroblasts. Due patented structure that laser, it possible with a beam combining two or three wavelengths. energy density 3 J/cm2, 25 64 J/cm2....

10.3390/jpm11020098 article EN Journal of Personalized Medicine 2021-02-04

Laser-induced periodic surface structures (LIPSS) are the sub-wavelength nanostructures generated by femtosecond laser. Implant topography and its nanostructural changes can be important for biomedical applications. In order to compare of different implants, appropriate mathematical physical descriptive methods should provided. The aim study was evaluate experimental LIPSS-based-Low Spatial Frequency LIPSS (LSFL) dental implant surfaces. Novel analysis, such as Fractal Dimension Analysis...

10.3390/ma15082713 article EN Materials 2022-04-07

The purpose of this study was histological and thermometric examination soft tissue de-epithelialization using digitally controlled laser handpiece (DCLH) - X-Runner.Commonly used techniques for include scalpel, abrasion with diamond bur, or a combination the two. Despite being simple, inexpensive effective, these are invasive may produce unwanted side effects. It is important to look alternative novel tools, which minimally effective.114 porcine samples sized 6 × mm were collected from...

10.1089/pho.2017.4413 article EN Photomedicine and Laser Surgery 2018-03-23

Chemical composition and physical parameters of the implant surface, such as roughness, regulate cellular response leading to bone osseointegration. Possible surface modifications include anodization or plasma electrolytic oxidation (PEO) treatment process that produces a thick dense oxide coating superior normal anodic oxidation. Experimental with Plasma Electrolytic Oxidation titanium alloy Ti6Al4V plates PEO additionally treated low-pressure oxygen (PEO-S) were used in this study evaluate...

10.3390/ijms24043603 article EN International Journal of Molecular Sciences 2023-02-10

Background.The main goal of the treatment peri-implantitis is to decontaminate surface implant, thereby enabling further involving, e.g., guided bone regeneration.Since new implants rougher were introduced common dental practice, decontamination even more difficult.Objectives.The aim study was evaluate 3 different methods decontaminating with surfaces. Material and methods.A total 30 types (machined, sandblasted, acid-etched (SLA) hydroxyapatite (HA)-coated) used in study.Each group coated...

10.17219/acem/112606 article EN cc-by Advances in Clinical and Experimental Medicine 2020-02-25

Biocompatibility is defined as "the ability of a biomaterial, prosthesis, or medical device to perform with an appropriate host response in specific application". especially important for restorative dentists they use materials that remain close contact living tissues long time. The research material involves six types cement used frequently the subgingival region: Ketac Fil Plus (3M ESPE, Germany), Riva Self Cure (SDI, Australia) (Glass Ionomer Cements), Breeze (Pentron Clinical, USA)...

10.3390/ma14195857 article EN Materials 2021-10-07

Oral leukoplakia represents the most common oral potentially malignant disorder, so early diagnosis of is important. The aim this study to propose an effective texture analysis algorithm for diagnosis. Thirty-five patients affected by were included in study. Intraoral photography normal mucosa and taken processed analysis. Two features texture, run length matrix co-occurrence matrix, analyzed. Difference was checked ANOVA. Factor classification artificial neural network performed. Results...

10.1155/2020/8831161 article EN cc-by Journal of Healthcare Engineering 2020-09-14

A noninvasive, accurate and quick diagnosis is very important to general practitioners specialists who care for the health of patients' oral cavity mucosa. The main enemies are precancerous lesions: leukoplakia lichen planus (LP).The aim this study was attempt formulate a differential vs LP in mucosa based on digital texture analysis intraoral macrophotography.The comprised 21 patients affected by leukoplakia, healthy volunteers. Intraoral photography all participants taken perpendicularly...

10.17219/acem/104524 article EN cc-by-nc-nd Advances in Clinical and Experimental Medicine 2019-03-20

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Zduniak K, Agrawal S, Symonowicz Jurczyszyn Ziółkowski P. The comparison of nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) with Ki67 proliferation marker expression in common skin tumors. Polish Journal Pathology. 2014;65(1):48-54. doi:10.5114/pjp.2014.42669. APA Zduniak, K., Agrawal, S., Symonowicz, Jurczyszyn, & Ziółkowski, (2014). Pathology, 65(1), 48-54....

10.5114/pjp.2014.42669 article EN cc-by-nc-sa Polish Journal of Pathology 2014-01-01

Background: The aim of the study was to compare effectiveness photodynamic therapy (PDT) steroid in treatment oral lichen planus (OLP). Due lack commercially available drug carriers, innovative proprietary solutions were used for both photosensitiser and carrier—in first case shorten second extend contact active substance with mucosa. Methods: A prospective, randomised, single-blind, 12-week full contralateral split-mouth clinical trial 30 patients bilateral conducted. prepared matrices...

10.3390/jcm10163673 article EN Journal of Clinical Medicine 2021-08-19

Orthodontic removable appliances made of transparent thermoplastic materials—aligners—are becoming increasingly popular in contemporary orthodontic practice. It is important for the clinician to fully understand mechanical properties and behavior appliance used. Because that, aim our study was investigate changes aligner surface after immersion Coca-Cola orange juice. For evaluation, fractal analysis, texture wetting angle measurement were performed. Statistically significant found between...

10.3390/ma15186341 article EN Materials 2022-09-13

Abstract Photodynamic therapy (PDT) is a well-known method for the treatment of malignant tumors, and its principles have been well established over past 30 years. This involves application chemical called photosensitizer subsequent excitation with light at appropriate wavelength energy. Topical photodynamic aminolevulinic acid (5-ALA) an alternative many processes, including nonmelanoma skin cancers such as basal-cell carcinoma (BCC). Our novel approach this study was to use liposomal...

10.2478/s11658-010-0033-1 article EN cc-by-nc-nd Cellular & Molecular Biology Letters 2010-01-01

The aim of the present study was to investigate immunohistochemical expression nuclear ubiquitous casein and cyclin-dependent kinases substrate 1 (NUCKS1) in invasive breast carcinoma no special type, association with clinicopathological characteristics, including tumor grade, frequency lymph node involvement distant metastasis. In addition, associations between NUCKS1 other subtype markers, estrogen receptor (ER), progesterone (PR), human epidermal growth factor 2 (HER2), Ki-67 cytokeratin...

10.3892/etm.2014.1847 article EN Experimental and Therapeutic Medicine 2014-07-16

The COVID-19 pandemic has spread very rapidly around the world. Various regional and national lockdowns were imposed to control spread. Meanwhile, vaccine development population vaccination next steps for control. Workers in dental field, both dentists assistants, however, close sources of aerosol generated during procedures thus group workers most exposed infection. aim our study was monitor immune response before after a high-risk population, composed by professionals.A clinical...

10.1186/s12879-023-08534-z article EN cc-by BMC Infectious Diseases 2023-08-18

Venous lake (VL) is a common lesion resulting from the enlargement of thin-walled veins surrounded by thick wall fibrous tissue. Photocoagulation becoming one basic methods for treating small vascular lesions. The aim this study was an application texture analysis (TA) and fractal dimension (FDA) to evaluate VL treatment. Twenty-three VLs were included in study. We used 980 nm diode laser, 6 W, 100 ms pulse mode with 50% duty cycle. total dose energy range 80 J 600 J. difference intensity...

10.3390/ma14154140 article EN Materials 2021-07-25
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