This study was designed to evaluate the effects of purple potato extract Blue Congo variety (PP) on diabetes and its antioxidant activities after two-week administration tostreptozotocin (STZ)-induced diabetic rats. The PP were evaluated at a dose 165 mg/kg body weight (b.w.) by estimating biochemical changes in blood plasma through histopathological kidney, muscles, liver tissue. We effect treatment with glucose level, glycated hemoglobin, enzymatic antioxidants (including superoxide...

Abstract Background Mesenchymal stem cells (MSCs) secrete a cocktail of growth factors and cytokines, which could promote tissue regeneration wound healing. Therefore, in clinical practice, post-culture MSC supernatant treatment be more attractive alternative to autologous cell transplantation. In this study, we compared the regenerative properties supernatants harvested from four newly established human adipose mesenchymal lines (HATMSCs) derived chronic patients or healthy donors. Methods...

Purpose: This study aimed to compare the histological characteristics of bone tissue following drilling with three implant systems under different rotational speeds and cooling conditions. Methods: A total 54 bed preparations were performed in four swine ribs using systems: Hiossen ET (Hiossen, Fairfield, NJ, USA), Paltop (Burlington, MA, Anyridge (Megagen, Daegu, Republic Korea). Drilling was at (800, 1200, 1500 rpm) conditions: saline room temperature, cooled 4 °C, no cooling. Histological...

The purpose of this study was to evaluate the effects Nd:YAG laser with flat-top handpiece on in vitro growth Candida albicans and Streptococcus mutans. incidence C. (opportunistic commensal) S. mutans (facultatively anaerobic) infections is increasing, despite available treatments. Cultures were irradiated using (LightWalker, Fotona) (Genova, LightWalker, at following parameters: group G1: 0.25 W, 10 Hz, 15 s, 3 J G2: 1 60s, 59 J. results evaluated directly 24 h after irradiation a...

Abstract Non-enzymatic modification of proteins by carbohydrates, known as glycation, leads to generation advanced glycation end-products (AGEs). In our study we used in vitro generated AGEs model vivo. We discovered vivo analogs unusual melibiose-adducts designated MAGEs (mel-derived AGEs) synthesized under anhydrous conditions with bovine serum albumin and myoglobin. Using nuclear magnetic resonance spectroscopy have identified a set isomers, open-chain cyclic structures, the fructosamine...

In our research we used the extract from dietary supplement of elderberry (EE) and its dominant anthocyanin—cyanidin 3-O-glucoside (Cy 3-gluc). By interacting with a model membrane that reflects main lipid composition tumor membranes, components, including Cy 3-gluc, caused an increase in packing order, mainly hydrophilic region membrane. It can thus be stated EE rigidifying effect, which is fundamental for understanding anticancer antioxidant activity. This study represents first attempt to...

Biocompatibility is defined as "the ability of a biomaterial, prosthesis, or medical device to perform with an appropriate host response in specific application". especially important for restorative dentists they use materials that remain close contact living tissues long time. The research material involves six types cement used frequently the subgingival region: Ketac Fil Plus (3M ESPE, Germany), Riva Self Cure (SDI, Australia) (Glass Ionomer Cements), Breeze (Pentron Clinical, USA)...

The purpose of the study was to assess effects different doses a phytobiotic mixture on selected production parameters and meat quality residue preparation in tissues possible toxic broiler chickens. Broiler chicks aged 160 days, divided into four equal groups, were supplemented with at doses, D1-0.5 mL/L, D2-1 D3-2 times during 42-day trial. There no statistically significant differences weight gain per week life mortality birds. also demonstrated that use phytobiotics had effect colour,...

The objective was to study the effect of type concentrate with varying starch and fibre content on growth gastrointestinal development in preweaned dairy calves. Thirty-two newborn Danish Holstein male calves were allocated four treatment groups eight blocks An experimental low-starch, high-molasses, high-fibre (EXP) or a traditional high-starch (TRA) fed either at high (HIGH; 2 × 3.2 kg/day) low (LOW; 1.6 whole milk allowance factorial design. TRA contained 350 EXP 107 g starch/kg dry...

In the article has been presented an analysis of susceptibility selected dental materials, made in CAD/CAM technology. The morphology and structural properties materials their composites were determined by using XRPD (X-ray powder diffraction) techniques, as well IR (infrared) spectroscopy. Moreover, adhesion development biofilm oral microorganisms studied. It shown that a degree on tested depended microorganism genus species. Streptococcus mutans demonstrated best to comparison with Candida...

Polychlorinated dibenzo-p-dioxins and dibenzofurans (dioxins) are classed as persistent organic pollutants have adverse effects on multiple functions within the body. Dioxins known carcinogens, immunotoxins, teratogens. transformed in vivo, interactions between products aryl hydrocarbon receptor (AhR) lead to formation of proinflammatory toxic metabolites. The aim this study was determine whether α-tocopherol (vitamin E), acetylsalicylic acid (ASA), levamisole can decrease amount damage...

Background: Recently, the defects of tooth surface in cervical region are often restored using composite filling materials. It should meet needs patients regarding esthetics and material stability. The aim study was to analyze root at after removal by means Erbium-doped Yttrium Aluminium Garnet (Er: YAG) laser or drill scanning electron microscopy (SEM) fluorescence microscopy. Materials Methods: For purposes this study, 14 premolar teeth (n = 14) were removed due orthodontic reasons....

The present study aimed to characterize the macrostructure and microstructure of mandibular teeth Komodo dragon (Varanus komodoensis) methods it uses obtain food. Examinations were performed using a stereoscopic microscope, autofluorescence method, histological method computed microtomography. A detailed macro- micro-structural description V. komodoensis made. are laterally flattened along their entire length dental crown is hooked caudally. part nasal margin tooth irregular, while caudal...

The use of stem cells for tissue regeneration is a prominent trend in regenerative medicine and engineering. In particular, dental pulp (DPSCs) have garnered considerable attention. When exposed to specific conditions, DPSCs the ability differentiate into osteoblasts odontoblasts. Scaffolds are critical cell differentiation because they replicate 3D microenvironment niche enhance adhesion, migration, differentiation. purpose this study present biological responses human purified chitin...

A series of novel silver(i) 2,2':6',2''-terpyridine (tpy), 4'-(4-methylphenyl)-2,2':6':2''-terpyridine (tpy-Ph-Me) and 1,10-phenanthroline-5,6-dione (dione) derivatives containing PTA (1,3,5-triaza-7-phosphaadamantane) or 1,3,5-triaza-7-phosphaadamantane-7-sulfide (PTA[double bond, length as m-dash]S) have been synthesized fully characterized. Two types complexes obtained, monocationic [Ag(tpy)(PTA)](NO3) (1), [Ag(tpy-Ph-Me)(PTA)](NO3) (2), [Ag(dione)(PTA[double m-dash]S)](BF4) (4)...

The aim of this work was the examination biological activity three selected racemic cis-β-aryl-δ-iodo-γ-lactones. Tested iodolactones differed in structure aromatic fragment molecule, bearing isopropyl (1), methyl (2), or no substituent (3) on para position benzene ring. A broad spectrum as antimicrobial, antiviral, antitumor, cytotoxic, antioxidant, and hemolytic examined. All showed bactericidal against Proteus mirabilis, lactones 1,2 were active Bacillus cereus. highest cytotoxic towards...

Ilex paraguariensis, the holly tree, is a plant with recognized biological properties, whose aqueous infusions are known as “Yerba mate”, that regulate lipid metabolism, reduce obesity, and improve brain stimulation. In present study, effect of standardized saponin terpenoid fractions European taxon, aquifolium, on blood biochemical parameters in rat model metabolic disorder, (fa/fa) Zucker, presented. The profiles volatile two species six varieties were investigated. After selecting best...

This study aimed to evaluate the impact of single and triple administration levamisole on dynamics hematological parameters during experimental pleuritis. The experiment was performed female Buffalo rats. Rats were randomly assigned two equal groups that received 1 3 doses every 2, 24 48 h, respectively. Following experiment, blood samples for measurement collected. group receiving three observed a significant reduction red cell count at h post an increase in mean corpuscular volume compared...

Human adenovirus 36 (HAdV-D36) is the only currently known infectious agent capable of promoting obesity in humans and animals, but effects on embryonated chicken egg (ECE) have not been described yet. In our study, we used ECEs as a model dynamically developing organism. The allantoic cavity yolk sack was inoculated with HAdV-D36 to simulate different routes infection. Each day, part embryos weighed histologically examined compared controls analyze pathological changes induced by virus. Our...

Human adenovirus 36 (HAdV-D36) is presently the sole virus identified to be associated with an elevated risk of obesity in both humans and animals. However, its impact on embryonated chicken eggs (ECEs) remains unexplored. This study endeavoured examine influence HAdV-D36 embryonic development by utilizing as a dynamic model. To simulate various infection routes, allantoic cavity yolk sac ECEs were inoculated HAdV-D36. Subsequently, embryos from experimental (inoculated virus) control PBS)...

(1) Background: This study aimed to evaluate the microporosity of tooth surface structure adjacent cemento-enamel junction (CEJ) after removal composite fillings with a drill in comparison by an Er:YAG laser and cleaning periodontal curette, chemical EDTA NaOCl (sodium hypochlorite) conditioning. (2) Methods: The research material consisted 30 extracted premolars cervical fillings. teeth were divided into six groups according method preparation: group G1 (n = 5)—a diamond drill; G2 +...