A5003270838- Reproductive tract infections research
- Polysaccharides Composition and Applications
- Advanced Drug Delivery Systems
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Microencapsulation and Drying Processes
- Proteins in Food Systems
- biodegradable polymer synthesis and properties
- Surgical Sutures and Adhesives
- Pregnancy and Medication Impact
- Polymer Science and Applications
- Humic Substances and Bio-Organic Studies
- Medical and Agricultural Research Studies
- Medicinal plant effects and applications
- Venomous Animal Envenomation and Studies
- Enzyme Catalysis and Immobilization
- Advancements in Transdermal Drug Delivery
- Phytoestrogen effects and research
- Advanced Scientific Research Methods
- Dental Erosion and Treatment
- Veterinary Pharmacology and Anesthesia
- Analytical Methods in Pharmaceuticals
- Proteoglycans and glycosaminoglycans research
- Erythrocyte Function and Pathophysiology
Wroclaw Medical University
2014-2023
Université de Lille
2023
University of Wrocław
2006-2017
This study aimed to evaluate the impact of single and triple administration levamisole on dynamics hematological parameters during experimental pleuritis. The experiment was performed female Buffalo rats. Rats were randomly assigned two equal groups that received 1 3 doses every 2, 24 48 h, respectively. Following experiment, blood samples for measurement collected. group receiving three observed a significant reduction red cell count at h post an increase in mean corpuscular volume compared...
A significant role is played in inflammation by the liver, which, stimulated inflammatory mediators, synthetizes plasma proteins with various dynamics. The purpose of these studies to generate a detailed dynamic analysis changes concentrations and serum protein fractions selected acute-phase as well nonspecific biochemical indices during course an induced pleurisy. were conducted on female inbred Buffalo rats, which divided into two groups: control group (C) experimental (IP) pleurisy was...
Vaginal candidiasis (VC) is an emerging global hardly treated health issue affecting millions of women worldwide. In this study, the nanoemulsion consisting clotrimazole (CLT), rapeseed oil, Pluronic F-68, Span 80, PEG 200, and lactic acid was prepared using high-speed high-pressure homogenization. Yielded formulations were characterized by average droplet size 52–56 nm, homogenous distribution volume, a polydispersity index (PDI) < 0.2. The osmolality nanoemulsions (NEs) fulfilled...
In developed countries, gastro-oesophageal reflux is one of the most frequently diagnosed diseases. Although acid more well known, alkaline equally troublesome. either two cases, oesophageal mucosa destroyed. The aim this study was to analyse possibility eliminating problem by using hydrogels containing dextran and chitosan prevent irritation mucosa. addition all tested gels increased their dynamic viscosity, enabling better adhesion and, consequently, protection mucous membrane. reduced pH...
Young children have an incompletely developed digestive tract and they are susceptible to numerous disorders due the return of acid alkaline content oesophagus. The aim study was analyse ability hydrogels containing chitosan polyvinyl alcohol prevent irritation oesophageal mucosa in children. addition tested gels increased their pH, which could be useful neutralise gastric reflux, dynamic viscosity. texture tests revealed that significantly work adhesion work.
The investigated powders on a methylcellulose base revealed good adhesion to the vaginal mucosa and were present it throughout daily activities of patient. This property enabled continuity 24-hour action drug. treatment vagina inflammatory conditions is usually long difficult because frequent relapse. Powders transformed into gels tested for their properties. Formulations prepared with varying pH rheological test showed work gels. All ratios lactic acid chitosan 1:1 2:1 in physiological...
Gynecological scientific journals report that traditional therapeutic regimens used to treat vaginal inflammation recommended by global treatment centers and health organizations are not producing satisfactory results. Insufficient duration of the drug’s contact with mucosa does provide adequate pH conditioning physiological biocenosis organ. The conducted research obtained positive results encourage further possibilities in field optimization pharmaceutical properties examined gynecological...
Gels obtained from powders containing lactic acid complexed with chitosan reveal a stoichiometric ratio of 1:1, 2:1, 3:1, 4:1 and 8:1. Their pH ranged 3.92 to 4.44 for 1:1 gels 2.36 2.84 the 8:1 ratio. The addition 5% polyvinylpyrrolidone K-90 increased 4.28 4.52 2.58 3.30 dynamic viscosity 84 510 mPa.s 47 386 possess work adhesion energy needed separate gel probe was 15.2 g/s K-15, 52.76 K-30, 56.6 K-90. results proved that it is possible produce preparation optimal pharmaceutical...
The investigations showed that the addition of a 20%, 23% and 25% poloxamer 407 increases adhesive properties investigated powders, but at same time it their pH. enrichment composition tested powders containing 5% glycerol 1,2-propylene glycol resulted in increased pH formulations. A modification has range dynamic viscosity hydroxypropylmethylcellulose decreased Laboratory tests have shown is possible to obtain thermosensitive gels with high adhesion vaginal mucous membrane.
Tested impact of polyvinyl alcohol, dextrane and calcium alginate for the properties powders containing poloxamer 407 lactic acid complexed with chitosan. For researches was prepared formulations different pH rheological properties. The thermosensitive gels obtained from possess work adhesion values. revealed that dynamic viscosity is high. A wide range allows selection optimum formulation. alcohol or were characterized by specific viscosity. demonstrated methylcellulose values significantly...
Research on gynaecological preparations followed that of optimising their pharmaceutical properties, which is beneficial for powders. Gels obtained from powders containing lactic acid complexed with chitosan revealed a stoichiometric ratio 1:1, 2;1, 3:1, 4:1 and 8:1. Their pH ranged 3.92 to 4.44 1:1 gels 2.36 2.84 the 8:1 ratio. The addition 5% polyethylene glycol-400 increases 4.52 4.92 2.54 3.41 A modification composition tested increased range dynamic viscosity formulations suitably 78...