A5103080830- Autophagy in Disease and Therapy
- MicroRNA in disease regulation
- Ginseng Biological Effects and Applications
- NF-κB Signaling Pathways
- Global Cancer Incidence and Screening
- Cancer Genomics and Diagnostics
- Immunotherapy and Immune Responses
- Circular RNAs in diseases
- Burn Injury Management and Outcomes
- Pancreatic function and diabetes
- interferon and immune responses
- Breast Cancer Treatment Studies
- Restraint-Related Deaths
- Wound Healing and Treatments
- Injury Epidemiology and Prevention
- Endoplasmic Reticulum Stress and Disease
- Mesenchymal stem cell research
- Berberine and alkaloids research
- Dermatologic Treatments and Research
Second Affiliated Hospital of Xi'an Jiaotong University
2019-2021
Anshan Hospital
2017
First Hospital of China Medical University
2017
China Medical University
2014
The antitumor effect of magnoflorine (Mag), an alkaloid isolated from Coptidis Rhizoma, in gastric cancer (GC) cells has not been reported. In the study, Mag suppressed proliferation GC cells, but showed no influence on normal cells. Mechanistically, induced autophagy as evidenced by up-regulated expression LC3B-II and increased autophagosome formation. Furthermore, we found that Mag-triggered autophagic cell death was regulated reactive oxygen species (ROS)-induced suppression...
Gastric cancer is one of the most common cancers leading to tumor-related deaths worldwide. Chicoric acid (CA) exhibits a variety protective effects in different diseases. However, its role regulating tumor progression has not been reported. Autophagy, as conserved catabolic process, sustains cellular homoeostasis responding stress modulate cell fate. In study, CA on gastric were investigated. The results indicated that treatment markedly reduced viability and induced apoptosis cells,...
X-linked ectodermal dysplasia receptor (XEDAR) is a new member of the tumor necrosis factor (TNFR) family that induces cell death. The purpose this study to determine tumor-suppressive potential XEDAR in development and differentiation gastric cancer (GC). levels were analyzed human GC tissues adjacent normal by immunohistochemistry (IHC), quantitative real-time reverse transcription PCR (RT-qPCR), Western blot analysis. We found expression was significantly downregulated further decreased...
Accidental injury due to burns is a serious and common, but preventable, occurrence in children. To analyze the characteristics of pediatric south Liaoning province China, retrospective review was conducted information, including general characteristics, demographics, etiology burns, anatomical areas burned, severity injuries, obtained from medical records burn patients admitted Burn Center Anshan Hospital First China Medical University 2002 2011. Differences between age-groups cause...