The relationship between body dissatisfaction (BD) and health-related quality of life (HRQoL) has been well documented in adolescents adults but is less clear children, particularly China. aims this study were to describe image perception examine their effects on HRQoL among primary school students Guangzhou, China.A total 5734 children aged 8-12 years from 29 schools completed self-report questionnaires, which included the Paediatric Quality Life Inventory 4.0 for measuring Ma figural...

Previous studies have shown significant sex differences in AD with regarding its epidemiology, pathophysiology, clinical presentation, and treatment response. However, the transcriptome variances associated remain unclear. RNA sequencing (RNA-seq) transcriptomic analyses were performed on peripheral blood samples from total of 54 patients, including male patients (n = 15), female 10), MCI 7), 11), healthy controls 6), 5). The snRNA-seq dataset (GSE167494, GSE157827) prefrontal cortex tissues...

Given the increase in COVID-19 emergency department visits and hospitalizations during winter of 2023–2024, identifying groups that have a high prevalence cases, severity, long-term symptoms can help efforts toward reducing disparities prevent severe outcomes. Using data from 2022 National Health Interview Survey (n = 27,651), we assessed outcomes (prior diagnosis, moderate/severe COVID-19, long COVID) by sociodemographic characteristics factors associated with each outcome. Approximately...

Objectives/Goals: Engaging interest holders in research is increasingly common, and guidelines include creating engagement plans. A detailed plan may be especially helpful when researchers perceive as difficult or less relevant. We tested whether a study’s translational stage an investigator’s years of experience affect their perceptions. Methods/Study Population: Since 2019, the Tufts Clinical Translational Science Institute Pilot Studies Program required applicants to submit plans engage...

This study aimed to investigate the relationship between proactive personality and career-related decision-making self-efficacy, with generative artificial intelligence acceptance serving as a mediating factor. Additionally, examined moderating effect of innovation competencies on this mediation pathway, utilizing moderated framework. The included 501 university students from Guangdong Province, China, who completed validated measures personality, acceptance, competencies. Data analysis was...

Influenza is associated with a large number of disease burdens, and it generally recommended that all healthcare workers (HCWs) get an influenza vaccination. However, the vaccination rates among HCWs are still low. This study aimed to assess HCWs' knowledge, attitude, practice (KAP) about vaccine, by establishing structural equation model (SEM) explore influencing factors medical personnel's in Chongqing, China.From September November 2019, we conducted cross-sectional survey four sentinel...

Chronic diseases for children pose serious challenges from a health management perspective. When not implemented in well-designed manner, an inefficient platform can have significant negative impact on patients and the utilization of care resources. Innovations recent years information technology, artificial intelligence machine learning provide possibilities to design implement knowledge-based systems platforms that follow-up, monitor advise child with chronic disease automated manner. In...

Purpose Understanding disparities in COVID-19 outcomes, overall and stratified by vaccination status, is important for developing targeted strategies to increase coverage protect adolescents from COVID-19. Design The 2022 National Health Interview Survey (NHIS) a cross-sectional nationally representative household survey of U.S. adults. Setting A probability sample households the Sample One child aged 12-17 years randomly selected each family household. knowledgeable adult (eg, parent or...

Understanding the extent of coronavirus disease 2019 (COVID-19) nonvaccination attributable to vaccine hesitancy versus other barriers can help prioritize approaches for increasing vaccination uptake. Using data from Centers Disease Control and Prevention's Research Development Survey, a nationally representative survey fielded May 1 June 30, 2021 (n = 5,458), we examined adjusted population attribution fraction (PAF) COVID-19 attributed according sociodemographic characteristics...

Introduction Despite recommendations for influenza and COVID-19 vaccines, studies have documented gaps disparities in vaccination coverage adults adolescents. Understanding the proportion demographics of those unvaccinated against and/or is important tailoring appropriate messaging strategies to increase confidence uptake.Methods Using 2021 National Health Interview Survey (NHIS), we assessed prevalence four patterns (exclusive vaccination, exclusive dual neither vaccination) by...

Transformational games, i.e. games that aim to transform their players for the better, are becoming increasingly popular ways help people engage with difficult topics. In our mobile game, BROKE: The Game (based on an original board game), we strive way view who live condition of poverty and have more empathy them. this paper discuss how adapted a game into designed promoting mechanics experience better understand what living in is like.

Objective To qualitatively explore the impact of anti-Asian racism in a Chinese community greater Boston area. Methods Individual semi-structured interviews (n = 27) were conducted between June and September 2021. Eligible participants ethnic immigrants living area, who recruited through community-based organization by word-of-mouth. Interviews Mandarin Cantonese translated into English. Data coded analyzed using directed approach to content analysis. Results The majority reported personal...

As the significance of inclusion prevalently predominate in recent years, educators and professionals draw their attention to students educational settings America.Including with learning disabilities general setting is a relatively debatable topic American society.The main goal this article explore importance inclusive education for both ordinary special needs students.It aims use critical discourse analysis examine how effectively represented among children early years.It also reveals...

Ischemic stroke seriously threatens human health, characterized by the high rates of incidence, disability, and death. Developing a reliable animal model that mimics most features is critical for pathological studies clinical research. In this study, we aimed to establish examine middle cerebral artery occlusion (MCAO) guided digital subtraction angiography (DSA) in cynomolgus monkeys.In 15 adult male monkeys were enrolled. Under guidance DSA, MCAO was established injecting an autologous...

OBJECTIVES/GOALS: Community and other stakeholder engagement (CSE) is critical for relevant equitable clinical research, yet implementation poses challenges. This study delineates the perspectives of scientists diverse stakeholders regarding facilitators challenges in CSE, its perceived value, their recommendations successful CSE. METHODS/STUDY POPULATION: The Tufts CTSI Pilot Studies Program requires applicants to propose a plan CSE while implementing award, including which (SHs)—community...

We measure the performance of in-context learning as a function task novelty and difficulty for open closed questions. For that purpose, we created novel benchmark consisting hard scientific questions, each paired with context various relevancy. show counter-intuitively, is more aligned topic does not always help than less relevant context. This effect especially visible questions high or novelty. result reveals fundamental difference between treatment close-form open-form by large-language...