Simona Maria Fragomeni

ORCID: 0000-0002-0719-3322
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About
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Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Cervical Cancer and HPV Research
  • Colorectal and Anal Carcinomas
  • Ovarian cancer diagnosis and treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Breast Cancer Treatment Studies
  • Sarcoma Diagnosis and Treatment
  • Cancer and Skin Lesions
  • Reconstructive Surgery and Microvascular Techniques
  • Microbial Inactivation Methods
  • Nonmelanoma Skin Cancer Studies
  • Genital Health and Disease
  • Surgical site infection prevention
  • Lymphatic System and Diseases
  • Cancer Diagnosis and Treatment
  • Breast Lesions and Carcinomas
  • Chemotherapy-related skin toxicity
  • Lung Cancer Research Studies
  • Medical Imaging Techniques and Applications
  • Cutaneous Melanoma Detection and Management
  • COVID-19 and healthcare impacts
  • Urological Disorders and Treatments
  • Economic and Financial Impacts of Cancer
  • Cancer survivorship and care
  • BRCA gene mutations in cancer

Agostino Gemelli University Polyclinic
2016-2025

University of Campania "Luigi Vanvitelli"
2025

Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025

Università Cattolica del Sacro Cuore
2015-2022

Objective: To create a comprehensive algorithmic approach to reconstruction after vulvar cancer ablative surgery, which includes both traditional and perforator flaps, evaluating anatomical subunits shape of the defect.Methods: We retrospectively reviewed 80 cases performed between June 2006 January 2016, transferring 101 flaps.We registered possibility achieve complete wound closure, even in presence very complex defects, postoperative complications.On basis these experience, analyzing...

10.3802/jgo.2016.27.e60 article EN cc-by-nc Journal of Gynecologic Oncology 2016-01-01

Groin dissection is the procedure with highest risk of lower limb lymphedema.As lymph stasis causes irreversible alterations to over time,therapies should be administered in early stages,or better yet, lymphatic drainage impairment prevented.We developed a new preventive approach lymphedema after groin dissection, and we report our preliminary experience.We enrolled 5 patients undergoing bilateral for vulvar cancer. Preoperative study limbs function was obtained by lymphoscintigraphy,...

10.1002/micr.30142 article EN Microsurgery 2016-12-17

ABSTRACT In centers with access to high‐end ultrasound machines and expert sonologists, is used detect metastases in regional lymph nodes from melanoma, breast cancer vulvar cancer. There is, as yet, no international consensus on assessment of any disease or medical condition. The lack standardized nomenclature describe makes it difficult compare results different studies find reliable features for distinguishing non‐infiltrated infiltrated by lymphoma cells. Vulvar International Tumor...

10.1002/uog.23617 article EN Ultrasound in Obstetrics and Gynecology 2021-06-01

ABSTRACT Objective To assess the accuracy of preoperative ultrasound examination for predicting lymph‐node (LN) status in patients with vulvar cancer. Methods This was a single‐institution retrospective observational study all women histological diagnosis cancer triaged to inguinal surgery within 30 days following evaluation between December 2010 and January 2016. For each groin examined, 15 morphological dimensional sonographic parameters associated suspicion LN involvement were examined. A...

10.1002/uog.20378 article EN Ultrasound in Obstetrics and Gynecology 2019-06-25

This retrospective study aimed to assess the diagnostic performance of preoperative [18F]FDG-PET/CT in predicting groin and pelvic lymph node (LN) status a large single-centre series vulvar cancer patients.Between January 2013 October 2018, among all consecutive women with proven submitted [18F]FDG-PET/CT, 160 patients were included. LNs analysed by two qualitative methods assessing PET information (defined as visual assessment) combination low-dose CT overall assessment), respectively, well...

10.1007/s00259-021-05257-8 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2021-02-23

The standard surgical treatment of early stage vulvar carcinoma < 4 cm consists resection the tumor with sentinel lymph node (SLN) biopsy (Oonk in Int J Gynecol Cancer 33:1023-1043, 2023). Video-endoscopic inguinal SLN indocyanine green (ICG) has been described (Capomacchia et al. Cancer, 2024). However, ICG induces fleeting mapping lymphatic pathways, making bilateral more challenging. aim this video is to show how perform by video-endoscopic approach. We present case an 81-year-old patient...

10.1245/s10434-025-17022-4 article EN cc-by Annals of Surgical Oncology 2025-03-06

Ablative surgery for vulvar cancer can involve the resection of perineum, vagina, urethra, groins, mons pubis, and abdominal wall creating complex defects. In our opinion, ALT flap is an ideal reconstruction, because low incidence complications, long pedicle outside radiotherapy field, capability carrying fascia muscle, possibility sensate donor site morbidity. The purpose this report to describe experience with reconstruction after extirpative surgery, discussing indications defects...

10.1002/micr.30077 article EN Microsurgery 2016-06-08

This study aimed to assess the value of dual-timepoint 18F-FDG PET/CT in prediction lymph node (LN) status patients with invasive vulvar cancer (VC) scheduled for inguinofemoral LN dissection. Methods: From April 2013 July 2015, all consecutive VC dissection were prospectively enrolled. All underwent a preoperative whole-body scan at 1 h (standard examination) and an additional from T11 groins 3 (delayed after injection. On both scans, each groin was visually scored 0 or concerning uptake...

10.2967/jnumed.117.194332 article EN Journal of Nuclear Medicine 2017-05-25

Abstract Introduction Pelvic lymphadenectomy (PL) causes changes to the inguinal lymph nodes with progressive loss of immune and lymphatic pump function. Efferent vessel‐to‐venous anastomosis (ELVA) has been reported address this problem. The aim report was describe feasibility SPECT/CT combined ultrasound fusion imaging (UFI) target groin efferent node (GELN) for ELVA. Patients Methods Twelve patients lower limb lymphedema after PL were scheduled peripheric lymphaticovenular (LVA)...

10.1002/micr.30501 article EN Microsurgery 2019-08-10
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