A5101813699- Physical Education and Gymnastics
- Musculoskeletal pain and rehabilitation
- Systemic Sclerosis and Related Diseases
- Osteoarthritis Treatment and Mechanisms
- Infrared Thermography in Medicine
- Healthcare Regulation
- Sports injuries and prevention
- Youth, Drugs, and Violence
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lower Extremity Biomechanics and Pathologies
- Sports Performance and Training
- Health, Nursing, Elderly Care
- Thermoregulation and physiological responses
- Cerebral Palsy and Movement Disorders
- Fibroblast Growth Factor Research
- Physical Education and Sports Studies
- Adventure Sports and Sensation Seeking
- Balance, Gait, and Falls Prevention
- Science and Education Research
- Health and Lifestyle Studies
- Pulmonary Hypertension Research and Treatments
- Exercise and Physiological Responses
- Breastfeeding Practices and Influences
Centro Universitário Adventista de São Paulo
2015-2024
Anhembi Morumbi University
2024
Universidade de São Paulo
2010-2024
Guarulhos University
2023
Universidade de Pernambuco
2021
Centro Universitário do Cerrado Patrocínio
2015-2021
Universidade Federal de São Paulo
2018
University of Évora
2018
University of Lusaka
2018
Centro Universitário de Franca
2013
Abstract Fibroblast growth factor receptor ( FGFR ) alterations drive oncogenesis in multiple tumor types. Here we studied pemigatinib, a selective, potent, oral FGFR1–FGFR3 inhibitor, the phase 2 FIGHT-207 basket study of FGFR- altered advanced solid tumors. Primary end points were objective response rate (ORR) cohorts A (fusions/rearrangements, n = 49) and B (activating non-kinase domain mutations, 32). Secondary progression-free survival, duration overall survival B, safety. Exploratory...
The aim of the present study was to examine relationship 20 m sprint performance with anthropometrical and physiological parameters in male soccer players. A hundred 81 players from region Athens (age 23.4 ± 5.0 yrs, body mass 73.4 7.7 kg, height 180.0 5.9 cm, fat (BF) 14.4 3.6%), classified into quartiles according time (group A, 2.84-3.03 s; group B, 3.04-3.09 C, 3.10-3.18 D, 3.19-3.61 s), participated. Soccer were younger had better vertical jumps Wingate anaerobic test (WAnT, p < 0.05)....
Abstract Background: Fibroblast growth factor receptor (FGFR) alterations are promising targets in different tumors. We report results of FIGHT-207, an open-label, single-arm phase 2 study pemigatinib, a potent, selective FGFR1-3 inhibitor, patients with previously treated unresectable or metastatic FGFR-altered solid tumors (NCT03822117). Methods: Patients were assigned to cohorts A (FGFR1-3 fusions), B activating non-kinase domain mutations), and C kinase mutations unknown significance)...
Pinto, ALS, Oliveira, NC, Gualano, B, Christmann, RB, Painelli, VS, Artioli, GG, Prado, DML, and Lima, FR. Efficacy safety of concurrent training in systemic sclerosis. J Strength Cond Res 25(5): 1423-1428, 2011-The optimal model for patients with sclerosis (SSc) is unknown. In this study, we aimed to investigate the effects a 12-week combined resistance aerobic program (concurrent training) SSc patients. Eleven no evidence pulmonary involvement were recruited exercise program. Lower upper...
O processo de envelhecimento envolve modificações no desempenho locomotor que podem predispor os idosos a quedas e alterações na qualidade vida. Objetivo: Comparar o medo cair, mobilidade funcional, força membros inferiores, estilo vida em sedentários praticantes caminhada. Método: Trata-se estudo transversal observacional do qual participaram 51 idosos, 25 caminhada (GCam) 26 (GSed), submetidos à avaliação funcional (Timed Up and Go - TUG), da inferiores (teste senta-levanta), cair (Escala...
Objective: To evaluate the exercise capacity of women with systemic sclerosis (SSc) without pulmonary involvement using a cardiopulmonary stress test.Methods: Thirteen consecutive female SSc patients [mean age 40.8±14 years, mean body mass index (BMI) 25.5±3.7 kg/m2] and cardiac 13 healthy sedentary controls (mean 41.6±9.1 BMI 23.7±3.8 kg/m2) matched by underwent maximum test (Bruce protocol). The following parameters were analysed: peak oxygen uptake (VO2peak), anaerobic threshold (AT),...
Several studies have established that systemic sclerosis patients a reduced exercise capacity when compared to healthy individuals. It is relevant evaluate whether aerobic in safe and effective intervention improve capacity. Seven without pulmonary impairment seven controls were enrolled an 8-week program consisting of moderate intensity exercise. Patients had significant improvement peak oxygen consumption (19.72±3.51 vs. 22.27±2.53 22.94±4.70 24.55±3.00, respectively, p=0.006), but...
ABSTRACT Objective To assess the influence of body weight in functional capacity and pain adult elderly individuals with knee osteoarthritis. Methods The sample consisted 107 patients osteoarthritis divided into two groups (adequate weight/adiposity excessive weight/adiposity) according to mass index percent fat mass, assessed by electric bioimpedance. Subjects were evaluated for mobility (Timed Up Go Test), pain, stiffness function (Western Ontario MacMaster Universities Osteoarthritis...
Resumo Introdução A hipertensão arterial sistêmica (HAS) atinge cerca de 30% da população adulta, sendo o maior fator risco para lesões cardíacas e cerebrovasculares, a terceira causa invalidez. Objetivo Determinar prevalência indivíduos com HAS os níveis conhecimento, tratamento controle doença, por meio um método diferenciado busca ativa. Método Realizou-se estudo transversal, base populacional, amostra representativa composta 409 adultos, na área abrangência uma Unidade Básica Saúde...
Purpose Evidence exists which suggests that a vegetarian diet is predisposing factor to erosive tooth wear. The aim of this study was assess the influence dietary pattern (vegetarian, lacto-ovo and omnivore) on Materials methods Two hundred seven subjects (29 vegetarians, 96 vegetarians 82 omnivores) underwent an oral assessment were asked answer questionnaires about care. Results Individuals who followed diets had statistically significantly more wear than did omnivores (p = 0.004)....
Osteoarthritis (OA) is the main cause of pain and disability in elderly. The disease leads to chronic musculoskeletal pain, characterized by an abnormal excitability conduction pathways, lifestyle may interfere this pathophysiological aspect. Thus, aim study was compare perceived pressure threshold, adult elderly women with without knee OA. A total 143 were recruited divided into 2 groups: OA (n = 68) control 75). Volunteers evaluated for tolerance (algometry vastus medialis lateralis...
Osteoarthritis is a common disease in which skin temperature may be included among the pathophysiological factors. Thermography allows mapping of cutaneous and employed investigation osteoarthritis.To evaluate lower limbs, as well to verify its association with pressure pain thresholds individuals knee osteoarthritis.This case series study was conducted both genders aged 48-77 years unilateral osteoarthritis. Volunteers underwent thermographic evaluation by an infrared sensor (FLIR T650SC)....
Aim: To evaluate the influence of swimming training on calcium responsiveness myocardium rats with different infarction sizes (MI). Method: female Wistar rats, sedentary sham (SS = 14), moderate MI (SMI 8) and large (SLI 10) were compared to trained (TS 16), (TMI 9) (TLI 10). After 4 weeks MI, animals swam for 60 min/day, 5 days/week, additional 8 weeks. Papillary muscles left ventricle subjected concentrations extracellular calcium. Inotropism was evaluated through developed tension (DT),...
Therapeutic climbing, an adaptation of sport can promote improvements in motor coordination, balance, and muscle endurance. Objective: The aim this study was to evaluate the effects intervention on handgrip strength, postural control, functional mobility, spasticity control children with cerebral palsy. Method: Case series 7 patients a mean age 9.6 ± 3.7 years, who took part 1-hour sessions therapeutic climbing twice week. Results: After 19 sessions, there increase strength right hand (p =...