A5078349973- Sleep and Wakefulness Research
- Circadian rhythm and melatonin
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Photoreceptor and optogenetics research
Air Force Medical University
2022-2024
Xijing Hospital
2022-2024
In mice, social defeat stress (SDS), an ethological model for psychosocial stress, induces sleep. Such sleep could enable resilience, but how promotes is unclear. Activity-dependent tagging revealed a subset of ventral tegmental area γ-aminobutyric acid (GABA)-somatostatin (VTA
ABSTRACT Background Dorsal raphe nucleus (DRN) serotonergic neurons projecting to the ventral tegmental area (VTA) neural circuit participate in regulating wake‐related behaviors; however, effect and mechanism of which sleep–wake are poorly understood. Methods Fiber photometry was used study DRN afferent activity changes VTA during processes. Optogenetics chemogenetics were took advantage effects afferents modulating sleep–wake. In vivo electrophysiology employed investigate how neuronal...
Abstract Background The lateral hypothalamus (LHA) is an evolutionarily conserved structure that regulates basic functions of organism, particularly wakefulness. To clarify the function LHA GABA neurons and their projections on regulating general anesthesia crucial for understanding excitatory inhibitory effects anesthetics brain. aim present study to investigate whether play either or a facilitatory role in sevoflurane‐induced anesthetic arousal regulation. Methods We used fiber photometry...