A5101453413- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Sulfur Compounds in Biology
- MicroRNA in disease regulation
- Eosinophilic Esophagitis
- Inhalation and Respiratory Drug Delivery
- Immunotherapy and Immune Responses
- Pregnancy and Medication Impact
- Advanced Nanomaterials in Catalysis
- Carbon and Quantum Dots Applications
- Computational Drug Discovery Methods
- Melanoma and MAPK Pathways
- IL-33, ST2, and ILC Pathways
- Autophagy in Disease and Therapy
East China University of Science and Technology
2023-2024
Hydrogen sulfide (H2S) is a toxic, essential gas used in various biological and physical processes has been the subject of many targeted studies on its role as new transmitter. These have mainly focused production pharmacological side effects caused by H2S. Therefore, effective strategies to remove H2S become key research topic. Furthermore, development novel nanoplatforms provided tools for removal This paper was performed review association between disease, related inhibitory drugs, well...
Abstract Ulcerative colitis is an inflammation of the colon characterized by immune dysregulation and intestinal inflammation. Developing safe oral nanomedicines that suppress inflammation, while modulating colonic inflammatory microenvironment scavenging reactive oxygen species (ROS) hydrogen sulfide (H 2 S) crucial for effective treatment colitis. Here, tofacitinib citrate copper coordination‐based nanoparticle (TF‐Cu nanoparticle, T‐C) to dual‐scavenge ROS H S coordination competition...
The increased risk of breast cancer metastasis is closely linked to the effects platelets. Our previously light-switchable diphtheria toxin A fragment (DTA) gene system, known as LightOn has demonstrated significant therapeutic potential; it lacks antimetastatic capabilities. In this study, we devised an innovative system by combining cell membrane fusion liposomes (CML) loaded with transgene DTA (pDTA) and a ticagrelor (Tig) prodrug. This named sequential rocket-mode bioactivating drug...