- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Neurogenesis and neuroplasticity mechanisms
- Neuroendocrine regulation and behavior
- Neural dynamics and brain function
- Neuroscience of respiration and sleep
- Neuroinflammation and Neurodegeneration Mechanisms
- Hypothalamic control of reproductive hormones
- Regulation of Appetite and Obesity
- Axon Guidance and Neuronal Signaling
- Photoreceptor and optogenetics research
- Reproductive Biology and Fertility
- Neurotransmitter Receptor Influence on Behavior
- Stress Responses and Cortisol
- Nitric Oxide and Endothelin Effects
- Head and Neck Surgical Oncology
- Mesenchymal stem cell research
- Zebrafish Biomedical Research Applications
- Retinal Development and Disorders
- Pain Mechanisms and Treatments
- Meningioma and schwannoma management
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Nerve injury and regeneration
- Sleep and Wakefulness Research
University of East Anglia
2023-2025
Aristotle University of Thessaloniki
2010-2023
University of Crete
2023
IMT Atlantique
2020
Institut de Recherche en Informatique et Systèmes Aléatoires
2020
401 General Military Hospital of Athens
1998
Université de Bordeaux
1990
University of Aberdeen
1989
Despite several studies showing that the rat supraoptic (SON) and paraventricular (PVN) nuclei are innervated by noradrenergic afferents, respective contribution of these inputs to oxytocinergic vasopressinergic neuronal populations remains be clearly defined. In present study, we used unbiased disector method estimate numerical density varicosities on identified somata in SON PVN. The analysis was carried out semithin (1 μm) plastic sections cut from vibratome slices (50 PVN which had been...
In the present study, poly(l-lactic acid) (PLLA) and poly(lactide-co-glycolide) (PLGA) hybrid nanoparticles were developed for intranasal delivery of galantamine, a drug used in severe to moderate cases Alzheimer's disease. Galantamine (GAL) was adsorbed first hierarchical porous carbon (HPC). Formulations characterized by FT-IR, which showed hydrogen bond formation between GAL HPC. Furthermore, became amorphous after adsorption, as confirmed XRD differential scanning calorimetry (DSC)...
Antisera raised against the monoamines serotonin (5-HT) and noradrenaline (NA) were employed in a study designed to provide detailed description of distribution, morphology, synaptic organization serotoninergic noradrenergic afferents lateral geniculate nucleus (LGN) rat. The distribution patterns two types immunoreactive fibers distinct largely complementary each other. NA axons particularly concentrated dorsal (LGd), with ventral (LGv) intergeniculate leaflet (IGL) receiving substantially...
Abstract In the present study, immunocytochemistry with an antiserum against dopamine (DA) revealed hitherto unknown terminal fields of DA axons in lateral geniculate nucleus (LGN) rat. The innervation all subdivisions LGN is achieved by a common set afferent fibers that branch to form uneven density. ventral (LGv) receives slightly more than dorsal (LGd), whereas within latter, afferents innervate part densely. Labeled axon terminals and varicosities, examined single serial ultrathin...
Abstract The morphology and distribution of somatostatinlike immunoreactive perikarya in the central nervous system hedgehog sheep have been studied by means peroxidase‐antiperoxidase immunohistochemical method. Intracerebroventricular colchicine infusion not only enhanced immunostaining but also revealed new cell bodies. In both neurons various forms, ranging from 12 to 28 μm diameter, were observed a number homologous brain structures. However, some species‐related differences noticed....
The cytoarchitecture of the claustrum in hedgehog (Erinaceus europaeus) brain, morphology its neurons, and efferent connections with cortical subcortical structures were studied Nissl Klüver-Barrera, Golgi, horseradish peroxidase methods. It was found that is a well developed nucleus telencephalon and, as other mammals, divided into dorsal ventral parts. In Golgi-stained sections, spiny multipolar cells are predominant neurons both projection neurons. Aspiny fewer, often beaded, dendrites...
Journal Article The frequency of chromosome anomalies in human preimplantation embryos after in-vitro fertilization Get access G. Papadopoulos, Papadopoulos 1 Department Obstetrics and Gynaecology, University Aberdeen, ForesterhillAberdeen AB9 2ZD, UK 1To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar A.A. Templeton, Templeton N. Fisk, Fisk J. Randall Human Reproduction, Volume 4, Issue 1, January 1989, Pages 91–98,...
Neural precursor cells (NPCs) located in the subgranular zone (SGZ) of dentate gyrus (DG) give rise to thousands new every day, mainly hippocampal neurons, which are integrated into existing neuronal circuits. Aging and chronic degenerative disorders have been shown impair neurogenesis, but consequence inflammation is somewhat controversial. The present study demonstrates that inflammatory environment prevailing brain experimental autoimmune encephalomyelitis (EAE) mice enhances...
Summary Ten dogs with primary ( n = 8) and metastatic 2) brain tumours were studied in an attempt to evaluate the diagnostic sensitivity of computed tomography (CT) or magnetic resonance imaging (MRI). Of clinical signs noticed, seizures (seven 10), behavioural abnormalities cognition dysfunction compulsive walking circling (six sensorimotor (five 10) neuro‐opthalmological (two most common. In all 10 animals that finally died disease killed, histopathological diagnosis followed necropsy was...
Abstract The distribution pattern and the morphology of vasoactive intestinal polypeptide (VIP)‐ cholecystokinin (CCK)‐like‐immunoreactive neurons were studied in brain hedgehog sheep by means peroxidase‐antiperoxidase immunocytochemical method. A total 34 hedgehogs 26 both sexes used. Fourteen 13 received an intracerebroventricular injection colchicine that enhanced immunostaining revealed “new” immunoreactive cell bodies. VIP‐immunoreactive bipolar multipolar observed species cerebral...
Data on first trimester human abortions have shown chromosome aberrations in ∼50% of the cases, most which were trisomies. More than 80% these trisomies been attributed to an error oocyte. In this study we investigated frequency anomalies 44 unfertilized oocytes and 13 uncleaved zygotes after insemination vitro. The aspirated from preovulatory follicles porous volunteer donors patients participating embryo replacement programme. Thirty cases could be analysed, 18 (60%) carried a abnormality....
ABSTRACT Structural and functional dissociation between the septal temporal part of dentate gyrus predispose for possible differentiations in ongoing neurogenesis process adult hippocampus. In this study, BrdU‐dated subpopulations rat (coexpressing GFAP, DCX, NeuN, calretinin, calbindin, S100, caspase‐3 or fractin) were quantified comparatively at 2, 5, 7, 14, 21, 30 days after BrdU administration order to examine successive time‐frames process, glial neuronal commitment newborn cells...