A5054130392- Pressure Ulcer Prevention and Management
- Antibiotic Resistance in Bacteria
- Medical Device Sterilization and Disinfection
- Acute Lymphoblastic Leukemia research
- Cancer therapeutics and mechanisms
- Infection Control and Ventilation
- Homelessness and Social Issues
- Infection Control in Healthcare
- DNA Repair Mechanisms
- COVID-19 and Mental Health
- Dermatology and Skin Diseases
- COVID-19 and healthcare impacts
- Geriatric Care and Nursing Homes
- Antibiotic Use and Resistance
- Skin Protection and Aging
- Psoriasis: Treatment and Pathogenesis
University of California, Irvine
2021-2024
University of North Carolina at Charlotte
2020
Importance Infections due to multidrug-resistant organisms (MDROs) are associated with increased morbidity, mortality, length of hospitalization, and health care costs. Regional interventions may be advantageous in mitigating MDROs infections. Objective To evaluate whether implementation a decolonization collaborative is reduced regional MDRO prevalence, incident clinical cultures, infection-related hospitalizations, costs, deaths. Design, Setting, Participants This quality improvement study...
We evaluated whether universal chlorhexidine bathing (decolonization) with or without COVID-19 intensive training impacted rates in 63 nursing homes (NHs) during the 2020-2021 Fall/Winter surge. Decolonization was associated a 43% lesser rise staff case-rates (
Abstract Background Decolonization (decol) and environmental cleaning are strategies to reduce MDRO transmission infection. While decol in NHs has been proven carriage, infection-related hospitalization, contamination, the impact of enhanced (EC) with or without not evaluated. Methods We performed a 4-phase study 2 from 2019–21 compare 1) decol, 2) EC, 3) plus EC on carriage contamination vs routine care (control). Decol involved nasal iodophor admission x 5d then M-F biweekly chlorhexidine...
Abstract Background Widespread CHG bathing to prevent infection has raised concerns about potential skin microbiome perturbations and depletion of commensal microbiota. Methods A prospective repeated measures cross-over study in NH residents/hospital patients evaluated the impact vs routine soap on nose/skin microbiome. Participants underwent serial visits during distinct phases (Figure) involving nares, axilla, groin, finger/hand swabs processed for MDROs, concentration (skin sites only),...
Abstract Background OC is the 6th largest U.S. county with 70 NHs. Universal decolonization (chlorhexidine for routine bathing, and twice daily nasal iodophor Mon-Fri every other week) was adopted in 24 NHs prior to COVID-19 pandemic, 12 (11 of those adopting decolonization) participated a COVID prevention training program rolling launch from July-Sept 2020. We evaluated impact these initiatives on staff resident cases. Methods conducted quasi-experimental study cases during CA winter surge...