Context: Syzygium polyanthum has been traditionally formulated by the folklore for treatment of diseases including diarrhea, rheumatism, diabetes mellitus, hypercholesterolemia, hypertension, gastritis and hyperuricemia. Normally, its phytochemicals are always extracted using solvent, maceration steam distillation methods, but use ultrasound-assisted extraction (UAE) method is still not well documented. Aims: This study aims to extract phytochemical compounds present in S. leaves UAE...

Ethnomedicinal plant is one of the important sources for drug discovery. Syzygium polyanthum (Wight) Walp ethnomedicinal plants that currently gaining attention its various pharmacological potentials. This review evaluates traditional uses, chemical profiles, toxicological aspects, nutritional values, as well properties. From our literature search in Science Direct, Scopus, and Google Scholar databases, it was found S. has valuable therapeutic potentials including antidiabetic,...

In the current era of globalization, synthetic dyes are one key factors water pollution. Photocatalysis constitutes a promising technology for treatment wastewater, especially to those containing hard-to-remove organic compounds. Zinc oxide nanoparticles (ZnONPs) play vital role as photocatalyst material. This research highlights synthesized ZnONPs with roselle flower and oil palm leaf extract. The extracts sodium hydroxide (NaOH) act reducing agents during synthesis process. Synthesis...

Status epilepticus is linked to cognitive decline due damage the hippocampus, a key structure involved in cognition. The hippocampus's high vulnerability epilepsy-related main reason for this impairment. Convulsive seizures, such as those observed status epilepticus, can cause various hippocampal pathologies, including inflammation, abnormal neurogenesis, and neuronal death. Interestingly, substantial evidence points therapeutic potential of sedative/hypnotic agent zolpidem...

Background/Objectives: Vascular function measurements, including central parameters [pulse wave velocity (PWV) and augmentation index (AI)], as well peripheral measures [finger photoplethysmography fitness (PPGF)], have been introduced to detect early vascular damage associated with coronary artery disease (CAD) risk factors. This study aimed compare marker levels among subjects hypertension (HPT), dyslipidemia, obesity. We also determine the relationship between these markers CAD factors...

Heterotrigona itama is a common stingless bee species found in Southeast Asia. Studies on the health benefits of its honey are limited comparison with other species. This study examines antiobesity (SBH) from H. . The parameters used to measure were weight change, morphological structures, and biochemical characteristics. research was conducted by using rats that given high‐fat diet (HFD). In total 48 male Sprague Dawley (SD) formulated HFD increase levels obesity, administered value 0.68...

Syzygium polyanthum (Wight) Walp. var. leaves are consumed as a traditional Malay treatment of hypertension. This study investigates hypotensive potential aqueous (AESP) and residual methanolic (met-AESP) extracts S. possible involvement autonomic receptors. AESP met-AESP (20 to 100 mg/kg) were intravenously administered into anaesthetized Wistar-Kyoto (WKY) spontaneously hypertensive (SHR) rats. Blood pressure heart monitored for 20 min. induced significant dose-dependent hypotension, but...

Abstract Background Despite the fact that natives of Southeast Asia have been consuming Prismatomeris glabra for decades a variety health benefits, research on this species is not as extensive other due to its limited distribution. The purpose study was determine cytotoxicity and identify bioactive compounds P. crude leaf extracts against MCF-7 cell line. Results We first examined potential cytotoxic activity using MTT assay line IC 50 plant at various concentrations three time points (24 h,...

Introduction . Pleurotus sajor-caju (PSC) is an edible oyster mushroom featuring high nutritional values and pharmacological properties. Objective To investigate the hypoglycemic antidiabetic effects of single repeated oral administration PSC aqueous extract in normal diabetic rats. Materials Methods A dose 500, 750, or 1000 mg/kg was given to experimental rats determine on blood glucose (BG) tolerance test (OGTT). The effective (750 mg/kg) repeatedly administrated daily for 21 days examine...

Diabetes mellitus (DM) is a known systemic disease with increasing global prevalence and multi-organ complications including diabetic nephropathy (DN). The trend of using medicinal plants in the management DM exponentially. Etlingera elatior plant that contains chemicals antioxidants delay oxidation process. However, available data focusing on its use DN are inconsistent scarce. This study aims to investigate antidiabetic nephroprotective effects E. flower aqueous extract (EEAE) type 2 rat...

Lignosus rhinocerotis Cooke. ( L . ) is a medicinal mushroom traditionally used in the treatment of asthma and several other diseases by indigenous communities Malaysia. In this study, effects on allergic airway inflammation hyperresponsiveness were investigated. extract (LRE) was prepared hot water extraction using soxhlet. Airway (AHR) study performed house dust mite (HDM)-induced Balb/c mice while ovalbumin (OVA)-induced Sprague-Dawley rats. Treatment with different doses LRE (125, 250...

Context: Aqueous decoction of Syzygium polyanthum (ADSP) leaf is one Malay traditionalremedial- preparations for hypertension. Intravenous ADSP reduced blood pressure anesthetized Wistar-Kyoto (WKY) and Spontaneously-Hypertensive rats (SHR); however, acute sub-acute effects oral on conscious its bioactive compound(s) are not comprehensively studied. This study aims to examine the in comparison methanol extract (MESP) systolic (SBP) WKY SHR rats, as well identify their major phenolic-compound...