- Indoor Air Quality and Microbial Exposure
- Air Quality and Health Impacts
- Allergic Rhinitis and Sensitization
- Mosquito-borne diseases and control
- Fungal and yeast genetics research
- Air Quality Monitoring and Forecasting
- Microbial Community Ecology and Physiology
- Endoplasmic Reticulum Stress and Disease
- Lichen and fungal ecology
- Vehicle emissions and performance
- Antifungal resistance and susceptibility
- Coastal wetland ecosystem dynamics
- Spaceflight effects on biology
- Genetics, Aging, and Longevity in Model Organisms
- Plant-Microbe Interactions and Immunity
- DNA Repair Mechanisms
- Wind and Air Flow Studies
- Urban Green Space and Health
- Infection Control and Ventilation
- Magnetic properties of thin films
- vaccines and immunoinformatics approaches
- Fermentation and Sensory Analysis
- Autophagy in Disease and Therapy
- Medical and Biological Ozone Research
- Plant and Fungal Interactions Research
Universidad de Murcia
2006-2024
Universidad Politécnica de Madrid
2016-2024
Universidad Nacional del Altiplano
2023
Pontificia Universidad Católica del Ecuador
2023
Comunidad de Madrid
2023
Universidad Complutense de Madrid
2006-2017
Institut de Microelectrònica de Barcelona
2017
Universitat Autònoma de Barcelona
2017
Université de Montréal
2015
Compared to soil or aquatic ecosystems, the atmosphere is still an underexplored environment for microbial diversity. In this study, we surveyed composition, variability and sources of microbes (bacteria fungi) in near surface a highly populated area, spanning ~ 4,000 Km2 around city center Madrid (Spain), different seasonal periods along two years. We found core abundant bacterial genera robust across space time, most origin, while fungi were more sensitive environmental conditions....
The urban atmosphere carries biological particles (bioaerosols) that may cause several diseases and allergies. These bioaerosols infiltrate mix with those present inside the buildings, including hospitals. However, little is known about behavior of these around health facilities. Here, we described composition an hospital indoor outdoor at two different periods (winter summer) using DNA sequencing. We observed seasonality was also displayed indoor, and, in some cases, taxa showed trends...
ABSTRACT Pollen, fungi, and bacteria are the main microscopic biological entities present in outdoor air, causing allergy symptoms disease transmission having a significant role atmosphere dynamics. Despite their relevance, method for monitoring simultaneously these particles metropolitan environments has not yet been developed. Here, we assessed use of Hirst-type spore trap to characterize global airborne biota by high-throughput DNA sequencing, selecting regions 16S rRNA gene internal...
Natural passive ventilation (windows opening) is frequently used in many houses and old buildings to renovate the air, remove unpleasant odors dust, reduce physicochemical pollutants indoor. However, little known about effect on biological particles such as pollen grains fungal spores (both allergenic) or bacteria (potentially infectious pathogenic). In present research, bioaerosols composition a small room naturally ventilated was analyzed by high-throughput DNA sequencing. Pollen were most...
Fission yeast mitogen-activated protein kinase (MAPK) Pmk1p is involved in morphogenesis, cytokinesis, and ion homeostasis as part of the cell integrity pathway, it becomes activated under multiple stresses, including hyper- or hypotonic conditions, glucose deprivation, wall-damaging compounds, oxidative stress. The only phosphatase known to dephosphorylate inactivate Pmp1p. We show here that stress-activated (SAPK) pathway its main effector, Sty1p MAPK, are essential for proper deactivation...
The receptor of activated C kinase (RACK1) is a protein highly conserved among eukaryotes. In mammalian cells, RACK1 functions as an adaptor to favor (PKC)-mediated phosphorylation and subsequent activation c-Jun NH(2)-terminal mitogen-activated kinase. Cpc2, the orthologue in fission yeast Schizosaccharomyces pombe, involved control G2/M transition interacts with Pck2, PKC-type member cell integrity Pmk1 (MAPK) pathway. Both Cpc2 are structural components 40S ribosomal subunit, recent data...
Microcystins (MCs) are frequently detected in cyanobacterial bloom-impacted waterbodies and introduced into agroecosystems via irrigation water. They widely known as phytotoxic cyanotoxins, which impair the growth physiological functions of crop plants. However, their impact on plant-associated microbiota is scarcely tackled poorly understood. Therefore, we aimed to investigate effect MCs microbiota-inhabiting bulk soil (BS), root adhering (RAS), tissue (RT) Vicia faba when exposed 100 μg...
Understanding the magnetic behaviour of multisegmented nanowires (NWs) is a major key for application such structures in future devices. In this work, magnetic/non-magnetic arrays FeCoCu/Cu multilayered NWs electrodeposited nanoporous alumina templates are studied. Contrarily to most reports on NWs, layer thickness was kept constant (30 nm) and only non-magnetic changed (0 80 nm). This allowed us tune interwire intrawire interactions between layers NW array creating three-dimensional (3D)...
Microbiologically influenced corrosion (MIC) has a significant cost to many industries, including naval engineering. In this case-of-study, three tugboats developed pitting in the carbon steel of inner hulls. Grade A was used for hull sheets but side (corroded) showed only two protective layers paint. The maintenance employed seawater, which ended up bilge and made MIC possible. Bilge's waters were submitted physicochemical, biological molecular tests. DNA analyses confirmed presence...
Centrifugation of cells Schizosaccharomyces pombe in liquid medium prompted a marked activation Sty1 and Pmk1, which are the effector mitogen-activated protein kinases (MAPKs) stress-activated kinase pathway cell-integrity pathway, respectively. Transduction centrifugation signals showed sensitivity threshold above response was dependent on time temperature. Centrifugation-induced phosphorylation Pmk1 required presence main functional components respective signalling cascades, i.e. Wak1 or...
Abstract Background Knowledge of the diversity invasion ligands in malaria parasites endemic regions is essential to understand how natural selection influences genetic these and their feasibility as possible targets for future vaccine development. In this study four genes merozoite was studied Ecuadorian isolates Plasmodium vivax . Methods Eighty-eight samples from P. infected individuals Coast Amazon region Ecuador were obtained between 2012 2015. The pvmsp-1-19 , pvdbpII pvrbp1a-2 pvama1...
It is well known that meteorology plays an important role in the diurnal evolution of pollutants, especially those variables related to atmospheric dispersion. Most studies typically relate concentration some pollutants with wind speed from conventional anemometers; however, use turbulence less common, part because needed instruments are not so typical standard air-quality stations. In this work, we compare wind-NO2 relationship turbulence-NO2 one using observational data two field campaigns...
Dust storms are known to be atmospheric phenomena that transport mineral dust but also airborne biological particles (bioaerosols) from desert areas distant regions. These bioaerosols can influence processes and they have the potential of changing composition local aerobiome in urban areas, which, recent years, been associated with allergies exacerbation respiratory syndromes. Here, we studied four events initiated Sahara Desert affecting center Iberian Peninsula. The before during were...
Cell fate is determined by the balance of conserved molecular mechanisms regulating death (apoptosis) and survival (autophagy). Autophagy a process which cells recycle their organelles macromolecules through degradation within vacuole in yeast plants, lysosome metazoa. In Schizosaccharomyces pombe, autophagy strongly induced under nitrogen starvation aging cells. Previously, we demonstrated that calnexin (Cnx1p), highly transmembrane chaperone endoplasmic reticulum (ER), regulates apoptosis...
In the fission yeast Schizosaccharomyces pombe, Wee1-dependent inhibitory phosphorylation of highly conserved Cdc2/Cdk1 kinase determines mitotic onset when cells have reached a defined size. The receptor activated C (RACK1) is scaffolding protein strongly among eukaryotes which binds to other proteins regulate multiple processes in mammalian cells, including modulation cell cycle progression during G1/S transition. We recently described that Cpc2, ortholog RACK1, controls from ribosome...