- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Pancreatic and Hepatic Oncology Research
- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders Research
- Nonmelanoma Skin Cancer Studies
- Cancer and Skin Lesions
- Pancreatitis Pathology and Treatment
- Case Reports on Hematomas
- Gallbladder and Bile Duct Disorders
- Head and Neck Cancer Studies
- Gout, Hyperuricemia, Uric Acid
- Vitamin D Research Studies
- Otitis Media and Relapsing Polychondritis
- Musculoskeletal pain and rehabilitation
- Therapeutic Uses of Natural Elements
- Tumors and Oncological Cases
- Pancreatic function and diabetes
- Inflammatory Bowel Disease
- Sarcoidosis and Beryllium Toxicity Research
- Renal and related cancers
- Pediatric Hepatobiliary Diseases and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
Westmead Hospital
2020-2024
St George Hospital
2019-2024
UNSW Sydney
2014-2024
University of Cambridge
2023
Sydney Local Health District
2022
Garvan Institute of Medical Research
2014-2022
Cambridge University Hospitals NHS Foundation Trust
2022
Addenbrooke's Hospital
2021
Thomas Jefferson University Hospital
2020
Thomas Jefferson University
2016
The American Joint Committee on Cancer (AJCC) substantially changed the staging of cutaneous squamous cell carcinoma (SCC) in seventh edition its manual. Although system is well established mucosal SCC, very little data are available prognostic value SCC.We conducted a multivariable analysis 672 patients with metastatic SCC from 2 prospective cancer center databases.The differentiation between N1 and N2 subgroups demonstrate importance whereas survival significantly worse for N3.Although...
The American Joint Committee on Cancer (AJCC) substantially changed the staging of cutaneous squamous cell carcinoma (cSCC) in seventh edition its manual. Given that oral mucosal (mSCC) and cSCC behave differently affect different patient populations, aim this study was to provide a side-by-side comparison evaluate current nodal (N) grouping for alongside mSCC determine whether same system is justified.Retrospective analysis prospectively collected data.Multivariable 672 patients with...
Severe spinal pain is an unusual presentation of gout. Due to its rarity and the difficulty obtaining joint fluid or tissue for crystal analysis, dual energy computed tomography (DECT) may be a useful imaging modality in management axial gout.Two patients independently presented major teaching hospital with severe subsequently shown due The first patient back fevers was initially thought have lumbar facet septic arthritis. second case pain. In both cases, DECT suggested monosodium urate...
To assess the diagnostic accuracy of temporal artery ultrasound compared with biopsy and clinical diagnosis in patients suspected giant cell arteritis (GCA) over 10 years an Australian center.Patients presenting to Westmead Hospital possible GCA from March 2011 December 2020 were retrospectively identified. The following parameters obtained medical record: presentation, inflammatory markers, findings, report. Data assembled a 2 × table; sensitivity specificity calculated.Over 10-year study...
The Group for Research and Assessment of Psoriasis Psoriatic Arthritis (GRAPPA) leadership congregated a strategic planning meeting before the 2022 GRAPPA annual in New York, USA. Meeting aims were to review GRAPPA’s performance relation its 2016 goals identify successes areas further improvement, key priorities activities next 5 years, explore committee structures best support these aims.
VDR expression has been found in many cell types involved metabolism, including the beta-cells of pancreatic islets. Activated vitamin D and its interactions with receptor (VDR) are implicated glucose homeostasis. We investigated metabolic phenotype VDR-null (VDRKO) mouse at early middle age. All offspring heterozygote VDRKO breeding-pairs were fed ‘rescue diet’ from weaning to normalize calcium phosphate levels avoid confounding by different diets. Glucose tolerance testing was performed 7...
Gout is a common chronic inflammatory disorder due to monosodium urate deposition, which results in severe arthritis. It particularly those of Māori or Pacific Islander heritage. There significant number this at-risk ethnic group western Sydney.To determine the healthcare burden gout Western Sydney.We characterised patients managed emergency departments (EDs) four Sydney Local Health District (WSLHD) hospitals and admitted for as primary secondary diagnosis from 1 January 2017 31 December...
At the Group for Research and Assessment of Psoriasis Psoriatic Arthritis (GRAPPA) 2022 annual meeting, Collaborative Network (CRN) met to present updates on several projects. These included GRAPPA-Industry biomarker projects, Axial Molecular Clinical Characterisation Study, Involvement in Cohort (AXIS) study, Health Initiatives Consortium European States (HIPPOCRATES). The meeting concluded with a discussion pathways further academia-industry collaboration.
Cryoglobulinaemic vasculitis is an immune complex-mediated with a myriad of clinical manifestations. We report rare case patient in her 60s rheumatoid arthritis who presented fever unknown origin, cutaneous leucocytoclastic and progressive pulmonary infiltrates cavitation. Extensive investigation for infectious aetiology was unrevealing. Blood investigations revealed high-titre factor, hypocomplementaemia, raised inflammatory markers the presence type 2 cryoglobulins. A diagnosis...