- Effects and risks of endocrine disrupting chemicals
- Breastfeeding Practices and Influences
- Air Quality and Health Impacts
- Per- and polyfluoroalkyl substances research
- Health, Environment, Cognitive Aging
- Asthma and respiratory diseases
- Climate Change and Health Impacts
- Indoor Air Quality and Microbial Exposure
- Prenatal Substance Exposure Effects
- Epigenetics and DNA Methylation
- Allergic Rhinitis and Sensitization
- Anesthesia and Neurotoxicity Research
- Diabetes Management and Education
- Stress Responses and Cortisol
- Gut microbiota and health
- Olfactory and Sensory Function Studies
- Quantum Electrodynamics and Casimir Effect
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmaceutical studies and practices
- Carcinogens and Genotoxicity Assessment
- Gestational Diabetes Research and Management
- Machine Learning in Healthcare
- Noise Effects and Management
- Toxic Organic Pollutants Impact
- Neonatal Respiratory Health Research
Boston Children's Hospital
2023-2024
Harvard University
2023-2024
University of Delaware
2019-2021
South College
2021
John Brown University
2018-2019
Brown University
2017-2019
Columbia University
2012
Background: Exposure to triclosan, an endocrine disrupting chemical, may affect thyroid hormone homeostasis and adversely neurodevelopment. Objective: Using a longitudinal pregnancy birth cohort, we investigated associations between triclosan exposures during different time windows, cognitive test scores at 8 y of age in 198 children from the HOME Study. Methods: We quantified urine samples mother–child pairs up nine times second trimester gestation age. The Wechsler Intelligence Scale for...
Diabetes case finding based on structured medical records does not fully identify diabetic patients whose histories related to diabetes are available in the form of free text. Manual chart reviews have been used but involve high labor costs and long latency.This study developed tested a Web-based algorithm using both unstructured electronic (EMRs).This was health information exchange (HIE) EMR database that covers almost all facilities state Maine, United States. Using narrative clinical...
Triclosan exposure may decrease circulating thyroxine levels or cause neuron apoptosis, which in turn adversely affect neurodevelopment. However, few studies have examined the association of early life triclosan with child behavior. To quantify between early-life and behavior at age 8-years 202 mother-child pairs from HOME study (Cincinnati, OH; enrolled: 2003–2006). We quantified urinary concentrations up to 3 times mothers (16-weeks, 26-weeks, delivery) 6 children (1, 2, 3, 4, 5, 8 years)....
Abstract Adipocytokines, which are secreted during fetal development by both mothers and fetuses, may influence lung development, but little human data available. We used from the HOME Study to investigate associations of cord blood adipocytokine concentrations with children’s forced expiratory volume (FEV1; N = 160) their risk wheeze ( 281). measured umbilical serum using enzyme-linked immunosorbent assays FEV1 a portable spirometer at ages 4 5 calculate percent predicted (%FEV1). Parents...
Background/Aim: Exposure to triclosan, an endocrine disrupting chemical, may decrease circulating thyroxine levels or interfere with thyroid hormone signaling during gestation early childhood neurodevelopment. In this study, we investigated associations of prenatal and postnatal triclosan exposure intellectual abilities among 199 children in the HOME Study birth cohort. Methods: We quantified up three maternal urine samples collected second third trimesters within 48 hours delivery. also...
Background: Early-life phthalate exposures may adversely affect children's neurodevelopment by disrupting thyroid function, reducing gonadal hormone levels, or altering concentrations of fatty acids in the brain. We attempted to identify windows heightened vulnerability during fetal period and early childhood.Methods: used data from 204 mother-child pairs HOME Study (Cincinnati, Ohio), a longitudinal pregnancy-birth cohort. quantified biomarkers urine samples collected up twice at...
Background: Triclosan may decrease circulating thyroxine levels or interfere with thyroid hormone signaling to adversely affect neurodevelopment. However, we are unaware of studies examining associations between triclosan exposure and childhood behavior problems.Methods: We used data from mother-child pairs enrolled in a Cincinnati, OH pregnancy birth cohort study 2003-2006 (The HOME Study). In 202 pairs, quantified urinary concentrations up 3 maternal samples collected 2nd trimester the...
OPS 23: Chemicals and cognitive function, Room 114, Floor 1, August 28, 2019, 1:30 PM - 3:00 Background/Aim: Triclosan exposure may affect thyroid hormone homeostasis subsequently adversely impact childhood cognition behavior. However, there are no studies examining the relationship between triclosan children's academic achievement. Thus, we estimated association gestational urinary concentrations with achievement scores. Methods: Using data from 193 8-year-old children HOME Study,...
TPS 752: Respiratory effects and allergies, Exhibition Hall, Ground floor, August 27, 2019, 3:00 PM - 4:30 Background/Aim: Per- polyfluoroalkyl substances (PFAS) are a class of persistent chemicals used as industrial surfactants, fire-fighting foams, textile treatments. Early childhood exposure to perfluorooctanoic acid (PFOA), perfluorooctane sulfonic (PFOS), perfluorononanoic (PFNA), perfluorohexane (PFHxS) may affect the immune system increase risk allergic respiratory diseases. Thus, we...