Adam J. Spanier

ORCID: 0000-0003-3108-3809
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About
Contact & Profiles
Research Areas
  • Asthma and respiratory diseases
  • Air Quality and Health Impacts
  • Effects and risks of endocrine disrupting chemicals
  • Climate Change and Health Impacts
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Heavy Metal Exposure and Toxicity
  • Noise Effects and Management
  • Trace Elements in Health
  • Smoking Behavior and Cessation
  • Child and Adolescent Health
  • Information and Cyber Security
  • Indoor Air Quality and Microbial Exposure
  • Per- and polyfluoroalkyl substances research
  • Allergic Rhinitis and Sensitization
  • Neuroscience of respiration and sleep
  • Cardiac Ischemia and Reperfusion
  • Pediatric health and respiratory diseases
  • Respiratory and Cough-Related Research
  • Ion channel regulation and function
  • Teaching and Learning Programming
  • Child Nutrition and Feeding Issues
  • Health, Environment, Cognitive Aging
  • Viral Infections and Outbreaks Research
  • Nitric Oxide and Endothelin Effects
  • Chemical Analysis and Environmental Impact

University of Maryland, Baltimore
2014-2023

University of Nebraska at Kearney
2023

University of Nebraska–Lincoln
2023

University of Nebraska at Omaha
2023

Uniformed Services University of the Health Sciences
2020

University of Maryland, College Park
2019-2020

Milken Institute
2018

George Washington University
2018

Penn State Milton S. Hershey Medical Center
2011-2015

Pennsylvania State University
2014

This Policy Statement was reaffirmed April 2021. Blood lead concentrations have decreased dramatically in US children over the past 4 decades, but too many still live housing with deteriorated lead-based paint and are at risk for exposure resulting lead-associated cognitive impairment behavioral problems. Evidence continues to accrue that commonly encountered blood concentrations, even those below 5 µg/dL (50 ppb), impair cognition; there is no identified threshold or safe level of blood....

10.1542/peds.2016-1493 article EN PEDIATRICS 2016-06-20

Ambient air pollution is produced by sources including vehicular traffic, coal-fired power plants, hydraulic fracturing, agricultural production, and forest fires. It consists of primary pollutants generated combustion secondary formed in the atmosphere from precursor gases. Air causes exacerbates climate change, change worsens health effects pollution. Infants children are uniquely sensitive to pollution, because their organs developing they have higher per body weight intake. Health linked...

10.1542/peds.2021-051484 article EN PEDIATRICS 2021-05-17

Bisphenol A (BPA), an endocrine-disrupting chemical that is routinely detected in > 90% of Americans, promotes experimental asthma mice. The association prenatal BPA exposure and wheeze has not been evaluated humans.We examined the relationship between early childhood.We measured concentrations serial maternal urine samples from a prospective birth cohort 398 mother-infant pairs assessed parent-reported child every 6 months for 3 years. We used generalized estimating equations with logit...

10.1289/ehp.1104175 article EN public-domain Environmental Health Perspectives 2012-02-14

Phthalates have antiandrogenic effects and may disrupt lipid carbohydrate metabolism. Racial/ethnic subpopulations been documented to varying urinary phthalate concentrations prevalences of childhood obesity.We examined associations between metabolites body mass outcomes in a nationally representative sample U.S. children adolescents.We performed stratified whole-sample cross-sectional analyses 2,884 6-19 years age who participated the 2003-2008 National Health Nutrition Examination Survey....

10.1289/ehp.1205526 article EN public-domain Environmental Health Perspectives 2013-02-11

Increasing scientific evidence suggests potential adverse effects on children's health from synthetic chemicals used as food additives, both those deliberately added to during processing (direct) and in materials that may contaminate part of packaging or manufacturing (indirect). Concern regarding additives has increased the past 2 decades because studies increasingly document endocrine disruption other effects. In some cases, exposure these is disproportionate among minority low-income...

10.1542/peds.2018-1410 article EN PEDIATRICS 2018-07-23

Rising global temperature is causing major physical, chemical, and ecological changes across the planet. There wide consensus among scientific organizations climatologists that these broad effects, known as climate change, are result of contemporary human activity. Climate change poses threats to health, safety, security. Children uniquely vulnerable threats. The effects on child health include physical psychological sequelae weather disasters, increased heat stress, decreased air quality,...

10.1542/peds.2015-3233 article EN PEDIATRICS 2015-10-27

Di-2-ethylhexylphthalate (DEHP) is an environmental chemical commonly found in processed foods. Phthalate exposures, particular to DEHP, have been associated with insulin resistance adults, but not studied adolescents.

10.1542/peds.2012-4022 article EN PEDIATRICS 2013-08-20

This Policy Statement was revised. See https://doi.org/10.1542/peds.2023-065504. Rising global temperatures are causing major physical, chemical, and ecological changes in the planet. There is wide consensus among scientific organizations climatologists that these broad effects, known as “climate change,” result of contemporary human activity. Climate change poses threats to health, safety, security, children uniquely vulnerable threats. The effects climate on child health include: physical...

10.1542/peds.2015-3232 article EN PEDIATRICS 2015-10-27

Triclosan and parabens are chemicals used in personal care medical products as microbicides preservatives. paraben exposure may be associated with allergy (atopy), but these associations have not been evaluated respect to other atopic states such eczema (atopic dermatitis). This study examines the of urinary triclosan concentrations allergic sensitization asthma children according history. We performed a cross-sectional analysis U.S. aged 6-18 years who participated National Health Nutrition...

10.2500/aap.2014.35.3803 article EN Allergy and Asthma Proceedings 2014-11-01

OBJECTIVE: To explore the relationship between tobacco smoke exposure (reported versus biomarker) and rates of readmission for children hospitalized asthma. METHODS: We enrolled a prospective cohort 774 aged 1 to 16 years admitted asthma or bronchodilator-responsive wheezing. The primary outcome was at least asthma- wheeze-related within year. Caregivers reported any home, in secondary residence, car. measured serum saliva cotinine levels with mass spectrometry. used logistic regression...

10.1542/peds.2013-2422 article EN PEDIATRICS 2014-01-21

<h3>Importance</h3> Bisphenol A (BPA), a prevalent endocrine-disrupting chemical, has been associated with wheezing in children, but few studies have examined its effect on lung function or wheeze older children. <h3>Objectives</h3> To test whether BPA exposure is function, wheeze, and pattern of children during their first 5 years. <h3>Design, Setting, Participants</h3> birth cohort study, enrolled early pregnancy the greater Cincinnati, Ohio, area among 398 mother-infant dyads. We...

10.1001/jamapediatrics.2014.1397 article EN JAMA Pediatrics 2014-10-06

<h3>Importance</h3> Ongoing climate change is affecting the health of communities across globe. While direct consequences, including morbidity and mortality tied to increases in frequency extreme weather events, have received significant attention, indirect effects, particularly those associated with change–driven disruptions ecosystems, are less understood. <h3>Objective</h3> To investigate how ongoing changes timing spring onset related rates asthma hospitalization Maryland. <h3>Design,...

10.1001/jamanetworkopen.2020.7551 article EN cc-by-nc-nd JAMA Network Open 2020-07-06

American children eat relatively little fish and shellfish in comparison with other sources of animal protein, despite the health benefits that eating may confer. At same time, be toxicants. This report serves to inform pediatricians about available research elucidates risks associated consumption childhood as well sustainability harvests.

10.1542/peds.2019-0999 article EN PEDIATRICS 2019-05-20

<h3>Importance</h3> Adenotonsillectomy (AT) is associated with improved behavior in children obstructive sleep apnea (OSA). However, it unknown whether polysomnographic parameters are superior to the parent-reported severity of sleep-disordered breathing (SDB) predicting behavioral changes after AT. <h3>Objective</h3> To ascertain vs SDB better predictors treatment-related OSA. <h3>Design, Setting, and Participants</h3> This ad hoc secondary analysis Childhood Trial (CHAT) downloaded...

10.1001/jamaoto.2020.2432 article EN JAMA Otolaryngology–Head & Neck Surgery 2020-09-03
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